Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sara L Al-Musawi"'
Autor:
Peter A. Barton, Peter Temple-Smith, Thomas D. Mueller, Kelly L. Walton, Emily K. Kelly, Craig A. Harrison, Yogeshwar Makanji, Sara L. Al-Musawi, Katharine E. Johnson
Publikováno v:
Molecular and Cellular Endocrinology. 422:84-92
Mature TGF-β proteins are used in vivo to promote bone growth, combat obesity, reverse fibrosis and pulmonary arterial hypertension, and as potential rejuvenation factors. However, the serum half-life of this family of growth factors is short (∼5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea85b5cddbee39f931257e00de82003
https://doi.org/10.1016/j.mce.2015.12.007
https://doi.org/10.1016/j.mce.2015.12.007
Autor:
Courtney M. Simpson, Robert B. Gilchrist, Kenneth P. McNatty, David G. Mottershead, Peter G. Stanton, Craig A. Harrison, David Robertson, D. A. Heath, Sara L. Al-Musawi, Lesley J. Ritter
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:E615-E624
Growth differentiation factor 9 (GDF9) is a central regulator of folliculogenesis and ovulation rate. Fourteen mutations in human (h) GDF9 have been reported in women with premature ovarian failure or polycystic ovarian syndrome as well as in mothers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62b5910c5ee90271c3f2c42b8a37f0e8
https://doi.org/10.1210/jc.2013-3949
https://doi.org/10.1210/jc.2013-3949
Publikováno v:
Reproduction. 133:1159-1168
Ovarian follicle development is regulated through endocrine and local mechanisms. Increasing evidence indicates roles for transforming growth factor β superfamily members, including inhibins and activins. We recently identified divergent expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a53d36c0e4be5c798cde755122db4db
https://doi.org/10.1530/rep-06-0179
https://doi.org/10.1530/rep-06-0179
Autor:
Craig A. Harrison, Junyan Shi, Melissa White, Thomas D. Mueller, Sara L. Al-Musawi, Georgia A. Martin, Satoshi Sugimura, Dulama Richani, Andrew P. Trotta, Robert B. Gilchrist, Lesley J. Ritter, Jing-Jie Li, David G. Mottershead
Growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) are oocyte-specific growth factors with central roles in mammalian reproduction, regulating species-specific fecundity, ovarian follicular somatic cell differentiation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819a7db339ffe2c9f3d0de1670e10fd7
Autor:
Louis Lu, Justin L. Chen, Paul Gregorevic, Assam El-Osta, Hongwei Qian, Kelly L. Walton, George O. Lovrecz, Emily Mae Kelly, Ross Lazarus, Mylinh La, Craig A. Harrison, Mark Ziemann, Sara L. Al-Musawi
Publikováno v:
BASE-Bielefeld Academic Search Engine
Soluble activin type II receptors (ActRIIA/ActRIIB), via binding to diverse TGF-β proteins, can increase muscle and bone mass, correct anemia or protect against diet-induced obesity. While exciting, these multiple actions of soluble ActRIIA/IIB limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659d6e74d9d232fde6a1854cf4bfce49
https://europepmc.org/articles/PMC4351455/
https://europepmc.org/articles/PMC4351455/
Publikováno v:
Endocrinology. 154(2)
Oocyte-derived bone morphogenetic protein 15 (BMP15) regulates ovulation rate and female fertility in a species-specific manner, being important in humans and sheep and largely superfluous in mice. To understand these species differences, we have com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228a57ce702806c6b1d301bfc11b47da
https://pubmed.ncbi.nlm.nih.gov/23284103
https://pubmed.ncbi.nlm.nih.gov/23284103
Publikováno v:
The Journal of experimental biology. 215(Pt 9)
Selective breeding has led to diverging phenotypic evolution in layer and broiler chickens through genomic and epigenetic modifications. Here we show that in ovo environmental manipulation differentially influences embryonic limb muscle phenotype in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8fa09b1a845bbb7be27202c5e1211e5
https://pubmed.ncbi.nlm.nih.gov/22496297
https://pubmed.ncbi.nlm.nih.gov/22496297
Publikováno v:
Reproduction (Cambridge, England). 134(2)
The aims were to examine ovarian expression of bone morphogenetic protein (BMP) ligands/receptor mRNAs in the chicken and to test the hypothesis that theca-derived BMP(s) modulates granulosa cell function in a paracrine manner. RT-PCR revealed expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::131990b15c52c31dc09934bcfbe1a130
https://pubmed.ncbi.nlm.nih.gov/17660239
https://pubmed.ncbi.nlm.nih.gov/17660239
Autor:
Jennifer Dean, Susanna Williams, Sara L Al-Musawi, James Bishton, Peter D. Weinberg, Stephanie G. Cremers
Publikováno v:
Atherosclerosis. 172(1)
The changes that occur with age in the distribution of atherosclerotic lesions around arterial branch points challenge accepted theories relating disease to haemodynamic stresses. We investigated whether flow near branch points changes with age in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a9ff7a497e1edb18b67ea9f78b6823
https://pubmed.ncbi.nlm.nih.gov/14709360
https://pubmed.ncbi.nlm.nih.gov/14709360
Publikováno v:
Differentiation; Research in Biological Diversity
With the human population predicted to reach 9 billion by 2050, increasing food supplies while maintaining adequate standards of animal welfare has become a global priority. In the poultry industry, broilers are genetically selected for greater pecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4e8f4099fad37b3accd98ce6198369