Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Sara L, Sawyer"'
Autor:
Qing Yang, Nicholas R. Meyerson, Camille L. Paige, James H. Morrison, Stephen K. Clark, Will T. Fattor, Carolyn J. Decker, Halley R. Steiner, Elena Lian, Daniel B. Larremore, Rushika Perera, Eric M. Poeschla, Roy Parker, Robin D. Dowell, Sara L. Sawyer
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTThe COVID-19 pandemic demonstrated the poor ability of body temperature to reliably identify SARS-CoV-2-infected individuals, an observation that has been made before in the context of other infectious diseases. While acute infection does not
Externí odkaz:
https://doaj.org/article/b08f948d7077422f9f70fcb6440dbffc
Autor:
Kevin C. Clark, Maximilian J. Bailey, Stefan Wasshuber, Raissa Huntley, Kristen K. Bjorkman, Leisha Conners Bauer, Camille L. Paige, Sara L. Sawyer, Michaila Czarnik, Margaret A. Riggs, Margaret J. Gutilla, Tanya L. Alderete
Publikováno v:
BMC Public Health, Vol 23, Iss 1, Pp 1-17 (2023)
Abstract Background Over the course of the COVID-19 pandemic, colleges and universities have focused on creating policies, such as mask mandates, to minimize COVID-19 transmission both on their campuses and in the surrounding community. Adherence to
Externí odkaz:
https://doaj.org/article/8d7bb67d42aa4076be1ae96746ab7191
Autor:
Cody J. Warren, Arturo Barbachano-Guerrero, Devra Huey, Qing Yang, Emma R. Worden-Sapper, Jens H. Kuhn, Sara L. Sawyer
Publikováno v:
STAR Protocols, Vol 4, Iss 2, Pp 102291- (2023)
Summary: We present a protocol to detect cells that have been infected by RNA viruses. The method, RNA fluorescence in situ hybridization flow cytometry (RNA FISH-Flow), uses 48 fluorescently labeled DNA probes that hybridize in tandem to viral RNA.
Externí odkaz:
https://doaj.org/article/1302b08db15f4b0793380e5d6e9e9620
Publikováno v:
eLife, Vol 12 (2023)
The H3N2 canine influenza virus – which originally came from birds – is evolving to become more transmissible between dogs.
Externí odkaz:
https://doaj.org/article/b48a613ed3cb4f908a19e3233c7c7fd9
Autor:
James M Burke, Nina Ripin, Max B Ferretti, Laura A St Clair, Emma R Worden-Sapper, Fernando Salgado, Sara L Sawyer, Rushika Perera, Kristen W Lynch, Roy Parker
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010930 (2022)
The antiviral endoribonuclease, RNase L, is activated by the mammalian innate immune response to destroy host and viral RNA to ultimately reduce viral gene expression. Herein, we show that RNase L and RNase L-mediated mRNA decay are primarily localiz
Externí odkaz:
https://doaj.org/article/9331648f7c5c4287a70e31fde9e1b2f9
Publikováno v:
BMC Ecology and Evolution, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background The Type I interferon response is an important first-line defense against viruses. In turn, viruses antagonize (i.e., degrade, mis-localize, etc.) many proteins in interferon pathways. Thus, hosts and viruses are locked in an evol
Externí odkaz:
https://doaj.org/article/54e5024de55f4b18939246ec584da09d
Autor:
Paul A Rowley, Aisha Ellahi, Kyudong Han, Jagdish Suresh Patel, James T Van Leuven, Sara L Sawyer
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 8 (2021)
AbstractThe gene encoding the ubiquitous DNA repair protein, Ku70p, has undergone extensive copy number expansion during primate evolution. Gene duplications of KU70KU70NUKUNUKUKU70NUKUNUKU2NUKUs
Externí odkaz:
https://doaj.org/article/e311a65e35ef468a9a235974803bf677
Autor:
Qing Yang, Nicholas R Meyerson, Stephen K Clark, Camille L Paige, Will T Fattor, Alison R Gilchrist, Arturo Barbachano-Guerrero, Benjamin G Healy, Emma R Worden-Sapper, Sharon S Wu, Denise Muhlrad, Carolyn J Decker, Tassa K Saldi, Erika Lasda, Patrick Gonzales, Morgan R Fink, Kimngan L Tat, Cole R Hager, Jack C Davis, Christopher D Ozeroff, Gloria R Brisson, Matthew B McQueen, Leslie A Leinwand, Roy Parker, Sara L Sawyer
Publikováno v:
eLife, Vol 10 (2021)
Here, we develop a simple molecular test for SARS-CoV-2 in saliva based on reverse transcription loop-mediated isothermal amplification. The test has two steps: (1) heat saliva with a stabilization solution and (2) detect virus by incubating with a p
Externí odkaz:
https://doaj.org/article/d52bb77200174523b04c7043a7af4511
Publikováno v:
Viruses, Vol 14, Iss 7, p 1451 (2022)
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in over 6 million deaths worldwide. The high variability in COVID-19 symptoms remains one of the most interesting mysteries of the pandemic. Gen
Externí odkaz:
https://doaj.org/article/db87145a56f447c0a59ebc3ac7eedfa0
Autor:
Cody J Warren, Nicholas R Meyerson, Obaiah Dirasantha, Emily R Feldman, Gregory K Wilkerson, Sara L Sawyer
Publikováno v:
PLoS Biology, Vol 17, Iss 6, p e3000304 (2019)
Individuals chronically infected with HIV-1 harbor complex viral populations within their bloodstreams. Recently, it has come to light that when these people infect others, the new infection is typically established by only one or a small number of v
Externí odkaz:
https://doaj.org/article/f7b74bd6027d48c4852a4340f5894289