Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Sara Kerselaers"'
Autor:
Cristina Martín-Escura, M. Ángeles Bonache, Jessy A. Medina, Alicia Medina-Peris, Jorge De Andrés-López, Sara González-Rodríguez, Sara Kerselaers, Gregorio Fernández-Ballester, Thomas Voets, Antonio Ferrer-Montiel, Asia Fernández-Carvajal, Rosario González-Muñiz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14894 (2023)
The protein transient receptor potential melastatin type 8 (TRPM8), a non-selective, calcium (Ca2+)-permeable ion channel is implicated in several pathological conditions, including neuropathic pain states. In our previous research endeavors, we have
Externí odkaz:
https://doaj.org/article/7af6439c3de94c3eb426edb908d81259
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13652 (2021)
Sex hormone steroidal drugs were reported to have modulating actions on the ion channel TRPM3. Pregnenolone sulphate (PS) presents the most potent known endogenous chemical agonist of TRPM3 and affects several gating modes of the channel. These inclu
Externí odkaz:
https://doaj.org/article/73f49fc8102049138e39989dc38f08be
Autor:
Koenraad Philippaert, Andy Pironet, Margot Mesuere, William Sones, Laura Vermeiren, Sara Kerselaers, Sílvia Pinto, Andrei Segal, Nancy Antoine, Conny Gysemans, Jos Laureys, Katleen Lemaire, Patrick Gilon, Eva Cuypers, Jan Tytgat, Chantal Mathieu, Frans Schuit, Patrik Rorsman, Karel Talavera, Thomas Voets, Rudi Vennekens
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Steviol glycosides are sweet-tasting compounds isolated from a South American shrub and are increasingly used as sweeteners in foods and beverages. Philippaertet al. demonstrate that steviol glycosides potentiate Ca2+-dependent TRPM5 activity and pro
Externí odkaz:
https://doaj.org/article/de9c509d79484c4cbf19eed74ada6127
Autor:
Andy Pironet, Ninda Syam, Frone Vandewiele, Chris Van den Haute, Sara Kerselaers, Silvia Pinto, Greetje Vande Velde, Rik Gijsbers, Rudi Vennekens
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Ca2+ activated non-selective (CAN) cation channels have been described in cardiomyocytes since the advent of the patch clamp technique. It has been hypothesized that this type of ion channel contributes to the triggering of cardiac arrhythmias. TRPM4
Externí odkaz:
https://doaj.org/article/e8682e0c0b014f83851cf9185a193c68
Clotrimazole-Based Modulators of the TRPM3 Ion Channel Reveal Narrow Structure–Activity Relationship
Autor:
Jan Pascal Kahler, Vincenzo Davide Aloi, Julia Miedes Aliaga, Sara Kerselaers, Thomas Voets, Joris Vriens, Steven H. L. Verhelst, Marta Barniol-Xicota
Publikováno v:
ACS Chemical Biology. 18:456-464
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa2809a2dd8550a243c5aa9c28d67397
https://doi.org/10.1021/acschembio.2c00672
https://doi.org/10.1021/acschembio.2c00672
Autor:
Frone Vandewiele, Andy Pironet, Griet Jacobs, Miklos Kecskés, Jörg Wegener, Sara Kerselaers, Lio Hendrikx, Joren Verelst, Koenraad Philippaert, Wouter Oosterlinck, Andrei Segal, Evy Van Den Broeck, Silvia Pinto, Silvia G Priori, Stephan E Lehnart, Bernd Nilius, Thomas Voets, Rudi Vennekens
Publikováno v:
European heart journal. 43(40)
Aims Cardiac arrhythmias are a major factor in the occurrence of morbidity and sudden death in patients with cardiovascular disease. Disturbances of Ca2+ homeostasis in the heart contribute to the initiation and maintenance of cardiac arrhythmias. Ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756766f0d323c47b3d8da0e5d0cee711
https://pubmed.ncbi.nlm.nih.gov/35822877
https://pubmed.ncbi.nlm.nih.gov/35822877
Autor:
Charlotte Van den Eynde, Katharina Held, Martina Ciprietti, Katrien De Clercq, Sara Kerselaers, Arnaud Marchand, Patrick Chaltin, Thomas Voets, Joris Vriens
Publikováno v:
European Journal of Pharmacology. 928:175086
The transient receptor potential (TRP) channel TRPV2 is widely expressed in a variety of different cell types and tissues. However, elucidating the exact biological functions of TRPV2 is significantly hampered by the lack of selective pharmacological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a383bb8bb13e49284f877b8767a7ee
https://doi.org/10.1016/j.ejphar.2022.175086
https://doi.org/10.1016/j.ejphar.2022.175086
Autor:
Peter Vangheluwe, Jan Eggermont, Susanne Smaardijk, Sara Kerselaers, Jialin Chen, Thomas Voets
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1865:855-862
The Secretory Pathway Ca2+ ATPases SPCA1 and SPCA2 transport Ca2+ and Mn2+ into the Golgi and Secretory Pathway. SPCA2 mediates store-independent Ca2+ entry (SICE) via STIM1-independent activation of Orai1, inducing constitutive Ca2+ influx in mammar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365dcc1b9595647dcb362e42eee3a142
https://doi.org/10.1016/j.bbamcr.2018.03.007
https://doi.org/10.1016/j.bbamcr.2018.03.007
Autor:
Frone Vandewiele, Andy Pironet, Rudi Vennekens, Ninda Syam, Sara Kerselaers, Silvia Pinto, Rik Gijsbers, Greetje Vande Velde, Chris Van den Haute
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 10 (2019)
Frontiers in Physiology, Vol 10 (2019)
Ca2+ activated non-selective (CAN) cation channels have been described in cardiomyocytes since the advent of the patch clamp technique. It has been hypothesized that this type of ion channel contributes to the triggering of cardiac arrhythmias. TRPM4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60c8275e2c25fc8c8221c4d2d0b67f1
https://pubmed.ncbi.nlm.nih.gov/31316392
https://pubmed.ncbi.nlm.nih.gov/31316392
Autor:
Tariq Ahmed, Koenraad Philippaert, Detlef Balschun, Rudi Vennekens, Victor Sabanov, Andrei Segal, Aurélie Menigoz, Marc Freichel, Sara Kerselaers, Thomas Voets, Bernd Nilius, Silvia Pinto
Publikováno v:
Pflugers Archiv
TRPM4 is a calcium-activated but calcium-impermeable non-selective cation (CAN) channel. Previous studies have shown that TRPM4 is an important regulator of Ca2+-dependent changes in membrane potential in excitable and non-excitable cell types. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b1b370aceeb3643f9e20a581511fd0
https://doi.org/10.1007/s00424-015-1764-7
https://doi.org/10.1007/s00424-015-1764-7