Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sara K. Watson"'
Autor:
A.R. Disanto, Thomas J. Hochadel, Richard J. Morales, Jeffrey S. Barrett, John Darnow, Shashank Rohatagi, Albert J. Azzaro, Sara K. Watson, Kimberly E. DeWitt
Publikováno v:
The Journal of Clinical Pharmacology. 37:238-247
Orally administered selegiline hydrochloride is a selective monoamine oxidase type B inhibitor at the recommended regimen of 10 mg/day, but it loses selectivity at higher doses. In bypassing first-pass metabolism, a 24-hour application of transdermal
Autor:
Anthony R. DiSanto, Jeffrey S. Barrett, Sara K. Watson, Thomas J. Hochadel, Richard J. Morales, Kimberly E. DeWitt, Shashank Rohatagi
Publikováno v:
American journal of therapeutics. 3(10)
This open-label, two-phase cross-over study compared the safety and pharmacokinetics of transdermally administered selegiline and orally administered selegiline hydrochloride in elderly men and women (n = 6/gender). Single oral doses of 10 mg selegil