Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sara K. Bengtsson"'
Autor:
Ming-De Wang, Torbjörn Bäckström, Maja Johansson, Roberta Diaz Brinton, Ronald W. Irwin, J. Sjöstedt, Sara K. Bengtsson
Publikováno v:
Neurobiology of Stress
Neurobiology of Stress, Vol 12, Iss, Pp-(2020)
Neurobiology of Stress, Vol 12, Iss, Pp-(2020)
Cognitive dysfunction, dementia and Alzheimer's disease (AD) are increasing as the population worldwide ages. Therapeutics for these conditions is an unmet need. This review focuses on the role of the positive GABA-A receptor modulating steroid allop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89174a00edf462af5b8d997533e94f0f
http://europepmc.org/articles/PMC6948369
http://europepmc.org/articles/PMC6948369
Publikováno v:
Hormones and Behavior. 78:160-167
Chronic stress in various forms increases the risk for cognitive dysfunction, dementia and Alzheimer's disease. While the pathogenesis behind these findings is unknown, growing evidence suggests that chronic increase in neurosteroid levels, such as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6531c61467654b4407857f7e48b3898f
https://doi.org/10.1016/j.yhbeh.2015.10.010
https://doi.org/10.1016/j.yhbeh.2015.10.010
Publikováno v:
Neuropsychobiology. 68:15-23
Background/Aims: Allopregnanolone or 3α-hydroxy-5α-pregnan-20-one (AlloP) is normally sedative and anxiolytic, but can under provoking circumstances paradoxically induce aggressive behavior. Therefore, it is of particular interest to determine if t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cbb24210efcc86b1f29f4573a1cec9f
https://doi.org/10.1159/000350478
https://doi.org/10.1159/000350478
Autor:
Ann Becker, Lorianne Rey-Bellet, Andrea Pfeifer, Michael T. Maloney, Pavel V. Belichenko, Anne Granet, Dorin Mlaki, Valérie Giriens, Sara K. Bengtsson, David T. Hickman, Andreas Muhs, Rime Madani, Adeline Plassard, Nishant Singhal, Rachel L. Nosheny, Maria Pihlgren, Long Do, Stephanie Vuillermot, Gordon R. Linke, Matthew L. Pearn, Janice S. Valletta, William C. Mobley, Pedro Reis, María Pilar López-Deber, Alexander M. Kleschevnikov, Eliezer Masliah
Publikováno v:
PLoS ONE
PloS one, vol 11, iss 3
PLoS ONE, Vol 11, Iss 3, p e0152471 (2016)
PloS one, vol 11, iss 3
PLoS ONE, Vol 11, Iss 3, p e0152471 (2016)
In Down syndrome (DS) or trisomy of chromosome 21, the β-amyloid (Aβ) peptide product of the amyloid precursor protein (APP) is present in excess. Evidence points to increased APP gene dose and Aβ as playing a critical role in cognitive difficulti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfba69d0dfcfb75e94cc602c199ebe4
http://europepmc.org/articles/PMC4811554
http://europepmc.org/articles/PMC4811554
Autor:
Inga-Maj Johansson, Sara K. Bengtsson, G.A. van Wingen, Mats Löfgren, David Haage, Lotta Andréen, Lindsey Ossewaarde, Sigrid Nyberg, Sahruh Turkmen, Torbjörn Bäckström, Jessica Strömberg
Publikováno v:
Neuroscience. 191:46-54
Some women have negative mood symptoms, caused by progestagens in hormonal contraceptives or sequential hormone therapy or by progesterone in the luteal phase of the menstrual cycle, which may be attributed to metabolites acting on the GABA-A recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c2ac741a6e2e6dce318001cb082634
https://doi.org/10.1016/j.neuroscience.2011.03.061
https://doi.org/10.1016/j.neuroscience.2011.03.061
Publikováno v:
Journal of Alzheimer's disease : JAD. 31(1)
The endogenous neurosteroid allopregnanolone alters neuronal excitability via modulation of the GABAA receptor and causes decreased neurotransmission. In Alzheimer's disease (AD), neurotransmission seems to alter the levels of toxic intracellular amy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76963545c5c3c4159efbc14a5f84c32b
https://pubmed.ncbi.nlm.nih.gov/22495347
https://pubmed.ncbi.nlm.nih.gov/22495347