Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sara K. Olofsson"'
Publikováno v:
Journal of Antimicrobial Chemotherapy. 60:795-801
The worldwide increase in antibiotic resistance is a concern for public health. When the appropriate antibiotic dosage is determined, the priorities are efficacy and toxicity. The aim of this thesis was to gain knowledge about the most efficient dosi
Publikováno v:
Antimicrobial Agents and Chemotherapy. 49:5081-5091
Antibiotic dosing regimens may vary in their capacity to select mutants. Our hypothesis was that selection of a more resistant bacterial subpopulation would increase with the time within a selective window (SW), i.e., when drug concentrations fall be
Publikováno v:
International journal of antimicrobial agents. 44(4)
Pharmacodynamic and mutant prevention properties of the fluoroquinolone pradofloxacin (PRA) were measured against a set of 17 Escherichia coli strains carrying no, one or two known mutations conferring reduced fluoroquinolone susceptibility. The stra
Autor:
Otto Cars, Sara K. Olofsson
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 45
The worldwide increase in antibiotic resistance is a concern for public health. The fact that the choice of dose and treatment duration can affect the selection of antibiotic-resistant mutants is becoming more evident, and an increased number of stud
Publikováno v:
The Journal of antimicrobial chemotherapy. 57(6)
To evaluate the mutant prevention concentrations (MPCs) of ciprofloxacin for two susceptible and one first-step gyrA resistant mutant Escherichia coli strains in an in vitro kinetic model and to identify the pharmacodynamic index that best predicts p
Publikováno v:
The Journal of antimicrobial chemotherapy. 55(6)
Antibiotic-resistant bacteria are increasingly a major healthcare problem but very few new classes of antibiotics have been discovered or launched in recent decades. Approaches to dealing with the problem include learning how bacteria evolve to resis
Publikováno v:
Journal of Antimicrobial Chemotherapy (JAC); Jun2006, Vol. 57 Issue 6, p1116-1121, 6p
Publikováno v:
Journal of Antimicrobial Chemotherapy (JAC); Jun2005, Vol. 55 Issue 6, p938-943, 6p