Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Sara K Lindén"'
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0308609 (2024)
Current prophylactic and disease control measures in aquaculture highlight the need of alternative strategies to prevent disease and reduce antibiotic use. Mucus covered mucosal surfaces are the first barriers pathogens encounter. Mucus, which is mai
Externí odkaz:
https://doaj.org/article/e3c7ce6507624f67be1843f410dc443b
Autor:
János Tamás Padra, Abarna V M Murugan, Kristina Sundell, Henrik Sundh, John Benktander, Sara K Lindén
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0215583 (2019)
Disease outbreaks are limiting factors for an ethical and economically sustainable aquaculture industry. The first point of contact between a pathogen and a host occurs in the mucus, which covers the epithelial surfaces of the skin, gills and gastroi
Externí odkaz:
https://doaj.org/article/8a586717fa634b358b64804e7e437fc3
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0204567 (2018)
Citrobacter rodentium infection is a model for infection with attaching and effacing pathogens, such as enteropathogenic Escherichia coli. The vasoactive intestinal peptide (VIP) has emerged as an anti-inflammatory agent, documented to inhibit Th1 im
Externí odkaz:
https://doaj.org/article/0bc34dd1724b4c1991f478f6d560436a
Autor:
Varvara Vitiazeva, Jayesh J Kattla, Sarah A Flowers, Sara K Lindén, Pushpa Premaratne, Birgitta Weijdegård, Karin Sundfeldt, Niclas G Karlsson
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130197 (2015)
Mucins are heavily O-glycosylated proteins where the glycosylation has been shown to play an important role in cancer. Normal epithelial ovarian cells do not express secreted mucins, but their abnormal expression has previously been described in epit
Externí odkaz:
https://doaj.org/article/55e354edd74a40fda2167a0d7edf9930
Autor:
Jenny K Gustafsson, Nazanin Navabi, Ana M Rodriguez-Piñeiro, Ala H A Alomran, Pushpa Premaratne, Harvey R Fernandez, Debashish Banerjee, Henrik Sjövall, Gunnar C Hansson, Sara K Lindén
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84430 (2013)
Citrobacter rodentium is an attaching and effacing pathogen used as a murine model for enteropathogenic Escherichia coli. The mucus layers are a complex matrix of molecules, and mucus swelling, hydration and permeability are affected by many factors,
Externí odkaz:
https://doaj.org/article/a2c97e7a8c9c4446b2615d3977753605
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68761 (2013)
Mucin glycoproteins are secreted in large quantities by mucosal epithelia and cell surface mucins are a prominent feature of the glycocalyx of all mucosal epithelia. Currently, studies investigating the gastrointestinal mucosal barrier use either ani
Externí odkaz:
https://doaj.org/article/d23d8566c87c443499832f2719e68915
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36378 (2012)
Helicobacter pylori colonizes the mucus niche of the gastric mucosa and is a risk factor for gastritis, ulcers and cancer. The main components of the mucus layer are heavily glycosylated mucins, to which H. pylori can adhere. Mucin glycosylation diff
Externí odkaz:
https://doaj.org/article/6a22a9baa31941c1870d51e2dbf6e095
Autor:
Sara K Lindén, Yong H Sheng, Alison L Every, Kim M Miles, Emma C Skoog, Timothy H J Florin, Philip Sutton, Michael A McGuckin
Publikováno v:
PLoS Pathogens, Vol 5, Iss 10, p e1000617 (2009)
The bacterium Helicobacter pylori can cause peptic ulcer disease, gastric adenocarcinoma and MALT lymphoma. The cell-surface mucin MUC1 is a large glycoprotein which is highly expressed on the mucosal surface and limits the density of H. pylori in a
Externí odkaz:
https://doaj.org/article/8088459c1b2e435baa2308dee51d9eab
Publikováno v:
PLoS ONE, Vol 3, Iss 12, p e3952 (2008)
BackgroundBacterial gastroenteritis causes morbidity and mortality in humans worldwide. Murine Citrobacter rodentium infection is a model for gastroenteritis caused by the human pathogens enteropathogenic Escherichia coli and enterohaemorrhagic E. co
Externí odkaz:
https://doaj.org/article/1cc7e253e5b84c81a2ed47dea3162bd2
Publikováno v:
Virulence. 13:1741-1751
Carbohydrates can both protect against infection and act as targets promoting infection. Mucins are major components of the slimy mucus layer covering the fish epithelia. Mucins can act as decoys for intimate pathogen interaction with the host afford
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88c9b9a6e5874a2561e1945ab8e3866e
https://doi.org/10.1080/21505594.2022.2132056
https://doi.org/10.1080/21505594.2022.2132056