Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sara Janowska"'
Autor:
Sara Janowska, Monika Wujec
Publikováno v:
Farmacja Polska, Vol 79, Iss 7, Pp 403-412 (2023)
Subject of research: Vaccinium uliginosum L. (swamp blueberry) and Vaccinium myrtillus L. (black blueberry) are species of the Vaccinium genus belonging to the Ericaceae family. The fruits of these plants are characterized by a high content of biolog
Externí odkaz:
https://doaj.org/article/6ad248aebd764ae997c0101a07bde89e
Autor:
Katarzyna Dziduch, Sara Janowska, Sylwia Andrzejczuk, Paulina Strzyga-Łach, Marta Struga, Marcin Feldo, Oleg Demchuk, Monika Wujec
Publikováno v:
Molecules, Vol 29, Iss 13, p 3023 (2024)
Heterocyclic compounds, particularly those containing azole rings, have shown extensive biological activity, including anticancer, antibacterial, and antifungal properties. Among these, the imidazole ring stands out due to its diverse therapeutic pot
Externí odkaz:
https://doaj.org/article/0404effa6aa048feb4f7ef19058cf88d
Publikováno v:
Molecules, Vol 29, Iss 6, p 1333 (2024)
The search for new antibacterial compounds is still a huge challenge for scientists. Each new chemotherapy drug is not 100% effective when introduced into treatment. Bacteria quickly become resistant to known structures. One promising group of new co
Externí odkaz:
https://doaj.org/article/3fbf94a4b31444048bff1197dee410eb
Publikováno v:
Molecules, Vol 29, Iss 2, p 346 (2024)
Aromatase is an enzyme that plays a crucial role in the biosynthesis of estrogens, which are hormones that contribute to the growth of certain types of breast cancer. In particular, aromatase catalyzes the conversion of androgens (male hormones) into
Externí odkaz:
https://doaj.org/article/7723771bfe3a416da326cb5751e78555
Publikováno v:
Molecules, Vol 28, Iss 14, p 5562 (2023)
A series of novel Mannich bases were designed, synthesized, and screened for their antimicrobial activity. The target compounds were synthesized from 4-(3-chlorophenyl)-5-(3-fluorophenyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione and different piperazin
Externí odkaz:
https://doaj.org/article/e8404888df2f4ccc8390e53ab4e89e77
Autor:
Sara Janowska, Dmytro Khylyuk, Michał Janowski, Urszula Kosikowska, Paulina Strzyga-Łach, Marta Struga, Monika Wujec
Publikováno v:
Molecules, Vol 28, Iss 6, p 2718 (2023)
The treatment of infectious diseases is a challenging issue faced by the medical community. The emergence of drug-resistant strains of bacteria and fungi is a major concern. Researchers and medical professionals are working to develop new and innovat
Externí odkaz:
https://doaj.org/article/fbf79734c0b7426b8475768d22fda31f
Autor:
Sara Janowska, Dmytro Khylyuk, Agnieszka Gornowicz, Anna Bielawska, Michał Janowski, Robert Czarnomysy, Krzysztof Bielawski, Monika Wujec
Publikováno v:
Molecules, Vol 27, Iss 20, p 6977 (2022)
Based on the results of previous work, we designed and synthesized 1,3,4-thiadiazole derivatives. The cytotoxic activity of the obtained compounds was then determined in biological studies using MCF-7 and MDA-MB-231 breast cancer cells and a normal c
Externí odkaz:
https://doaj.org/article/17fea5fc95494af3888fe98d775bd558
Publikováno v:
Molecules, Vol 27, Iss 10, p 3161 (2022)
The emergence of drug-resistant bacterial strains continues to be one of the major challenges of medicine. For this reason, the importance of searching for novel structures of antibacterial drugs chemically different from the currently known antibiot
Externí odkaz:
https://doaj.org/article/0efe04efa8444ac7950577fcf498d4f7
Autor:
Sara Janowska, Dmytro Khylyuk, Anna Bielawska, Anna Szymanowska, Agnieszka Gornowicz, Krzysztof Bielawski, Jarosław Noworól, Sławomir Mandziuk, Monika Wujec
Publikováno v:
Molecules, Vol 27, Iss 6, p 1814 (2022)
We designed and synthesized the 1,3,4-thiadiazole derivatives differing in the structure of the substituents in C2 and C5 positions. The cytotoxic activity of the obtained compounds was then determined in biological studies using MCF-7 and MDA-MB-231
Externí odkaz:
https://doaj.org/article/870e9885ca5947bfa0e0d5325bceb542
Publikováno v:
Molecules, Vol 25, Iss 18, p 4309 (2020)
During recent years, small molecules containing five-member heterocyclic moieties have become the subject of considerable growing interest for designing new antitumor agents. One of them is 1,3,4-thiadiazole. This study is an attempt to collect the 1
Externí odkaz:
https://doaj.org/article/b1394bc8ff2b43968fd4d2376d936ffa