Zobrazeno 1 - 10 of 50 pro vyhledávání: '"Sara J. Felts"'
1
Akademický článek
Widespread Non-Canonical Epigenetic Modifications in MMTV-NeuT Breast Cancer
Autor: Sara J. Felts, Virginia P. Van Keulen, Michael J. Hansen, Michael P. Bell, Kathleen Allen, Alem A. Belachew, Richard G. Vile, Julie M. Cunningham, Tanya L. Hoskin, V. Shane Pankratz, Larry R. Pease
Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 17, Iss 4, Pp 348-357 (2015)
Breast tumors in (FVB × BALB-NeuT) F1 mice have characteristic loss of chromosome 4 and sporadic loss or gain of other chromosomes. We employed the Illumina GoldenGate genotyping platform to quantitate loss of heterozygosity (LOH) across the genome
Externí odkaz: https://doaj.org/article/6938c8ff23b747c088d2f20b8e4c5faf
Zobrazit plný text záznamu
3
Data from Integrative Genome-Wide Analysis of Long Noncoding RNAs in Diverse Immune Cell Types of Melanoma Patients
Autor: Yuji Zhang, Larry R. Pease, Svetomir N. Markovic, Matthew S. Block, Adam D. Scheid, Virginia P. Van Keulen, Sara J. Felts, Lei Wang
Genome-wide identification and characterization of long noncoding RNAs (lncRNA) in individual immune cell lineages helps us better understand the driving mechanisms behind melanoma and advance personalized patient treatment. To elucidate the transcri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9f0afaf780eda3ba193c181b0f038c04
https://doi.org/10.1158/0008-5472.c.6510092.v1
Zobrazit plný text záznamu
4
Supplementary Figure S1, S2, S3, S4, S5, S6 from Integrative Genome-Wide Analysis of Long Noncoding RNAs in Diverse Immune Cell Types of Melanoma Patients
Autor: Yuji Zhang, Larry R. Pease, Svetomir N. Markovic, Matthew S. Block, Adam D. Scheid, Virginia P. Van Keulen, Sara J. Felts, Lei Wang
Figure S1: The cell-/tissue-specificity of lncRNA expression. Figure S2: The co-expression modules analyses in CD4+, CD8+, and CD14+ PBCs. Figure S3: The lncRNAs associated with PD-1 checkpoint pathways. Figure S4: The histogram of the number of lncR
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847a6ee795a1c6043f9b6321450992eb
https://doi.org/10.1158/0008-5472.22418321.v1
Zobrazit plný text záznamu
5
Supplementary Table S9, S10 from Integrative Genome-Wide Analysis of Long Noncoding RNAs in Diverse Immune Cell Types of Melanoma Patients
Autor: Yuji Zhang, Larry R. Pease, Svetomir N. Markovic, Matthew S. Block, Adam D. Scheid, Virginia P. Van Keulen, Sara J. Felts, Lei Wang
Table S9: The information of lncRNAs associated with H3K4me3 and H3K36me3 (including immune-associated, translation-associated, and differentially expressed lncRNAs), i.e., the number of lncRNAs with H3K4me3 and H3K36me3 peaks in the region of +/- 3
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9e64863baa31c421b0cd6dd72b8c40
https://doi.org/10.1158/0008-5472.22418300
Zobrazit plný text záznamu
7
Abstract P4-09-03: Phenotypes of breast tumor cells and normal lymphocytes are determined by the integration of minor changes in expression of multiple genes: A new dimension in quantitative inheritance
Autor: Larry R. Pease, Sara J. Felts, Krishna R. Kalari, Xiaojia Tang, Adam D. Scheid
Publikováno v: Cancer Research. 80:P4-09
Breast tumors develop under environmental pressures with phenotypically variant cells generated by mutation and epigenetic changes providing the substrate for clonal selection. Chromosomal mutations are a feature of spontaneous breast tumors in the B
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5786b752dd17386f87d195db8f218690
https://doi.org/10.1158/1538-7445.sabcs19-p4-09-03
Zobrazit plný text záznamu
8
Gene Expression Signatures Characterized by Longitudinal Stability and Interindividual Variability Delineate Baseline Phenotypic Groups with Distinct Responses to Immune Stimulation
Autor: Barry K. Gilbert, Robert W. Techentin, Adam D. Scheid, Steven C. Neier, Larry R. Pease, Yuji Zhang, Sara J. Felts, Virginia P. Van Keulen, Claudia Neuhauser, Asha Nair, Sumit Middha, Jin Jen
Publikováno v: The Journal of Immunology. 200:1917-1928
Human immunity exhibits remarkable heterogeneity among individuals, which engenders variable responses to immune perturbations in human populations. Population studies reveal that, in addition to interindividual heterogeneity, systemic immune signatu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2227505a70282e1f3cce456e6b9387ec
https://doi.org/10.4049/jimmunol.1701099
Zobrazit plný text záznamu
9
Akademický článek
Indirect recruitment of a CD40 signaling pathway in dendritic cells by B7-DC cross-linking antibody modulates T cell functions.
Autor: Suresh Radhakrishnan, Rosalyn Cabrera, Kristina M Bruns, Virginia P Van Keulen, Michael J Hansen, Sara J Felts, Larry R Pease
Publikováno v: PLoS ONE, Vol 4, Iss 4, p e5373 (2009)
The human IgM B7-DC XAb protects mice from tumors in both therapeutic and prophylactic settings. Its mechanism of action is mediated by its binding to B7-DC/PD-L2 molecules on the surface of dendritic cells (DCs) to induce a multimolecular cap and su
Externí odkaz: https://doaj.org/article/e0d5b76c9b404b55bfdbbe0d736ae236
Zobrazit plný text záznamu
10
Stochastic changes in gene expression promote chaotic dysregulation of homeostasis in clonal breast tumors
Autor: Krishna R. Kalari, Xiaojia Tang, Sara J. Felts, Michael J. Hansen, Virginia P. Van Keulen, Benjamin Willett, Larry R. Pease
Publikováno v: Communications Biology
Communications Biology, Vol 2, Iss 1, Pp 1-7 (2019)
Cells within tumors vary in phenotype as a result of changes in gene expression caused by a variety of mechanisms, permitting cancers to evolve under selective pressures from immune and other homeostatic processes. Earlier, we traced apparent losses
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8310a1c085311d0842cdb355bf93a513
http://europepmc.org/articles/PMC6570763
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje