Sleep-dependent engram reactivation during hippocampal memory consolidation associated with subregion-specific biosynthetic changes

Autor: Lijing Wang, Lauren Park, Weisheng Wu, Dana King, Alexis Vega-Medina, Frank Raven, Jessy Martinez, Amy Ensing, Katherine McDonald, Zhongying Yang, Sha Jiang, Sara J. Aton

Publikováno v: iScience, Vol 27, Iss 4, Pp 109408- (2024)

Summary: Post-learning sleep is essential for hippocampal memory processing, including contextual fear memory consolidation. We labeled context-encoding engram neurons in the hippocampal dentate gyrus (DG) and assessed reactivation of these neurons a

Externí odkaz: https://doaj.org/article/e27399db4b6e4b269675924c94f4c187

Enriched binocular experience followed by sleep optimally restores binocular visual cortical responses in a mouse model of amblyopia

Autor: Jessy D. Martinez, Marcus J. Donnelly, Donald S. Popke, Daniel Torres, Lydia G. Wilson, William P. Brancaleone, Sarah Sheskey, Cheng-mao Lin, Brittany C. Clawson, Sha Jiang, Sara J. Aton

Publikováno v: Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)

Abstract Studies of primary visual cortex have furthered our understanding of amblyopia, long-lasting visual impairment caused by imbalanced input from the two eyes during childhood, which is commonly treated by patching the dominant eye. However, th

Externí odkaz: https://doaj.org/article/dbb6611b59904a658e252a2b635719ee

The Engram’s Dark Horse: How Interneurons Regulate State-Dependent Memory Processing and Plasticity

Autor: Frank Raven, Sara J. Aton

Publikováno v: Frontiers in Neural Circuits, Vol 15 (2021)

Brain states such as arousal and sleep play critical roles in memory encoding, storage, and recall. Recent studies have highlighted the role of engram neurons–populations of neurons activated during learning–in subsequent memory consolidation and

Externí odkaz: https://doaj.org/article/60aeb78370a849dba070d6598af305c7

26th Annual Computational Neuroscience Meeting (CNS*2017): Part 3

Autor: Adam J. H. Newton, Alexandra H. Seidenstein, Robert A. McDougal, Alberto Pérez-Cervera, Gemma Huguet, Tere M-Seara, Caroline Haimerl, David Angulo-Garcia, Alessandro Torcini, Rosa Cossart, Arnaud Malvache, Kaoutar Skiker, Mounir Maouene, Gianmarco Ragognetti, Letizia Lorusso, Andrea Viggiano, Angelo Marcelli, Rosa Senatore, Antonio Parziale, S. Stramaglia, M. Pellicoro, L. Angelini, E. Amico, H. Aerts, J. Cortés, S. Laureys, D. Marinazzo, I. Bassez, L. Faes, Hannes Almgren, Adeel Razi, Frederik Van de Steen, Ruth Krebs, Hannelore Aerts, Lida Kanari, Pawel Dlotko, Martina Scolamiero, Ran Levi, Julian Shillcock, Christiaan P.J. de Kock, Kathryn Hess, Henry Markram, Cheng Ly, Gary Marsat, Tom Gillespie, Malin Sandström, Mathew Abrams, Jeffrey S. Grethe, Maryann Martone, Robin De Gernier, Sergio Solinas, Christian Rössert, Marc Haelterman, Serge Massar, Valentina Pasquale, Vito Paolo Pastore, Sergio Martinoia, Paolo Massobrio, Cristiano Capone, Núria Tort-Colet, Maria V. Sanchez-Vives, Maurizio Mattia, Ali Almasi, Shaun L. Cloherty, David B. Grayden, Yan T. Wong, Michael R. Ibbotson, Hamish Meffin, Luke Y. Prince, Krasimira Tsaneva-Atanasova, Jack R. Mellor, Alberto Mazzoni, Manuela Rosa, Jacopo Carpaneto, Luigi M. Romito, Alberto Priori, Silvestro Micera, Rosanna Migliore, Carmen Alina Lupascu, Francesco Franchina, Luca Leonardo Bologna, Armando Romani, Sára Saray, Werner Van Geit, Szabolcs Káli, Alex Thomson, Audrey Mercer, Sigrun Lange, Joanne Falck, Eilif Muller, Felix Schürmann, Dmitrii Todorov, Robert Capps, William Barnett, Yaroslav Molkov, Federico Devalle, Diego Pazó, Ernest Montbrió, Gabriela Mochol, Habiba Azab, Benjamin Y. Hayden, Rubén Moreno-Bote, Pragathi Priyadharsini Balasubramani, Srinivasa V. Chakravarthy, Vignayanandam R. Muddapu, Medorian D. Gheorghiu, Bartul Mimica, Jonathan Withlock, Raul C. Mureșan, Jennifer L. Zick, Kelsey Schultz, Rachael K. Blackman, Matthew V. Chafee, Theoden I. Netoff, Nicholas Roberts, Vivek Nagaraj, Andrew Lamperski, Logan L. Grado, Matthew D. Johnson, David P. Darrow, Davide Lonardoni, Hayder Amin, Stefano Di Marco, Alessandro Maccione, Luca Berdondini, Thierry Nieus, Marcel Stimberg, Dan F. M. Goodman, Thomas Nowotny, Veronika Koren, Valentin Dragoi, Klaus Obermayer, Samy Castro, Mariano Fernandez, Wael El-Deredy, Kesheng Xu, Jean Paul Maidana, Patricio Orio, Weiliang Chen, Iain Hepburn, Francesco Casalegno, Adrien Devresse, Aleksandr Ovcharenko, Fernando Pereira, Fabien Delalondre, Erik De Schutter, Peter Bratby, Andrew R. Gallimore, Guido Klingbeil, Criseida Zamora, Yunliang Zang, Patrick Crotty, Eric Palmerduca, Alberto Antonietti, Claudia Casellato, Csaba Erö, Egidio D’Angelo, Marc-Oliver Gewaltig, Alessandra Pedrocchi, Ilja Bytschok, Dominik Dold, Johannes Schemmel, Karlheinz Meier, Mihai A. Petrovici, Hui-An Shen, Simone Carlo Surace, Jean-Pascal Pfister, Baptiste Lefebvre, Olivier Marre, Pierre Yger, Athanasia Papoutsi, Jiyoung Park, Ryan Ash, Stelios Smirnakis, Panayiota Poirazi, Richard A. Felix, Alexander G. Dimitrov, Christine Portfors, Silvia Daun, Tibor I. Toth, Joanna Jędrzejewska-Szmek, Nadine Kabbani, Kim T. Blackwel, Bahar Moezzi, Natalie Schaworonkow, Lukas Plogmacher, Mitchell R. Goldsworthy, Brenton Hordacre, Mark D. McDonnell, Nicolangelo Iannella, Michael C. Ridding, Jochen Triesch, Reinoud Maex, Karen Safaryan, Volker Steuber, Rongxiang Tang, Yi-Yuan Tang, Darya V. Verveyko, Alexey R. Brazhe, Andrey Yu Verisokin, Dmitry E. Postnov, Cengiz Günay, Gabriella Panuccio, Michele Giugliano, Astrid A. Prinz, Pablo Varona, Mikhail I. Rabinovich, Jack Denham, Thomas Ranner, Netta Cohen, Maria Reva, Nelson Rebola, Tekla Kirizs, Zoltan Nusser, David DiGregorio, Eirini Mavritsaki, Panos Rentzelas, Nikul H. Ukani, Adam Tomkins, Chung-Heng Yeh, Wesley Bruning, Allison L. Fenichel, Yiyin Zhou, Yu-Chi Huang, Dorian Florescu, Carlos Luna Ortiz, Paul Richmond, Chung-Chuan Lo, Daniel Coca, Ann-Shyn Chiang, Aurel A. Lazar, Jennifer L. Creaser, Congping Lin, Peter Ashwin, Jonathan T. Brown, Thomas Ridler, Daniel Levenstein, Brendon O. Watson, György Buzsáki, John Rinzel, Rodica Curtu, Anh Nguyen, Sahand Assadzadeh, Peter A. Robinson, Paula Sanz-Leon, Caroline G. Forlim, Lírio O. B. de Almeida, Reynaldo D. Pinto, Francisco B. Rodríguez, Ángel Lareo, Caroline Garcia Forlim, Aaron Montero, Thiago Mosqueiro, Ramon Huerta, Francisco B. Rodriguez, Vinicio Changoluisa, Vinícius L. Cordeiro, César C. Ceballos, Nilton L. Kamiji, Antonio C. Roque, William W. Lytton, Andrew Knox, Joshua J. C. Rosenthal, Svitlana Popovych, Liqing Liu, Bin A. Wang, Tibor I. Tóth, Christian Grefkes, Gereon R. Fink, Nils Rosjat, Abraham Perez-Trujillo, Andres Espinal, Marco A. Sotelo-Figueroa, Ivan Cruz-Aceves, Horacio Rostro-Gonzalez, Martin Zapotocky, Martina Hoskovcová, Jana Kopecká, Olga Ulmanová, Evžen Růžička, Matthias Gärtner, Sevil Duvarci, Jochen Roeper, Gaby Schneider, Stefan Albert, Katharina Schmack, Michiel Remme, Susanne Schreiber, Michele Migliore, Carmen A. Lupascu, Luca L. Bologna, Stefano M. Antonel, Jean-Denis Courcol, Sami Utku Çelikok, Eva M. Navarro-López, Neslihan Serap Şengör, Rahmi Elibol, Neslihan Serap Sengor, Mustafa Yasir Özdemir, Tianyi Li, Angelo Arleo, Denis Sheynikhovich, Akihiro Nakamura, Masanori Shimono, Youngjo Song, Sol Park, Ilhwan Choi, Jaeseung Jeong, Hee-sup Shin, Sadra Sadeh, Padraig Gleeson, R. Angus Silver, Alexandra Pierri Chatzikalymniou, Frances K. Skinner, Lazaro M. Sanchez-Rodriguez, Roberto C. Sotero, Loreen Hertäg, Owen Mackwood, Henning Sprekeler, Steffen Puhlmann, Simon N. Weber, David Higgins, Laura B. Naumann, Ramakrisnan Iyer, Stefan Mihalas, Valentina Ticcinelli, Tomislav Stankovski, Peter V. E. McClintock, Aneta Stefanovska, Predrag Janjić, Dimitar Solev, Gerald Seifert, Ljupčo Kocarev, Christian Steinhäuser, Mehrdad Salmasi, Stefan Glasauer, Martin Stemmler, Danke Zhang, Chi Zhang, Armen Stepanyants, Julia Goncharenko, Lieke Kros, Neil Davey, Chris de Zeeuw, Freek Hoebeek, Ankur Sinha, Roderick Adams, Michael Schmuker, Maria Psarrou, Maria Schilstra, Benjamin Torben-Nielsen, Christoph Metzner, Achim Schweikard, Tuomo Mäki-Marttunen, Bartosz Zurowski, Daniele Marinazzo, Luca Faes, Sebastiano Stramaglia, Henry O. C. Jordan, Simon M. Stringer, Elżbieta Gajewska-Dendek, Piotr Suffczyński, Nicoladie Tam, George Zouridakis, Luca Pollonini, Mojtaba Madadi Asl, Alireza Valizadeh, Peter A. Tass, Andreas Nold, Wei Fan, Sara Konrad, Heiko Endle, Johannes Vogt, Tatjana Tchumatchenko, Juliane Herpich, Christian Tetzlaff, Jannik Luboeinski, Timo Nachstedt, Manuel Ciba, Andreas Bahmer, Christiane Thielemann, Eric S. Kuebler, Joseph S. Tauskela, Jean-Philippe Thivierge, Rembrandt Bakker, María García-Amado, Marian Evangelio, Francisco Clascá, Paul Tiesinga, Christopher L. Buckley, Taro Toyoizumi, Alexis M. Dubreuil, Rémi Monasson, Alessandro Treves, Davide Spalla, Sophie Rosay, Florence I. Kleberg, Willy Wong, Bruno de Oliveira Floriano, Toshihiko Matsuo, Tetsuya Uchida, Domenica Dibenedetto, Kâmil Uludağ, Abdorreza Goodarzinick, Maximilian Schmidt, Claus C. Hilgetag, Markus Diesmann, Sacha J. van Albada, Michael Fauth, Mark van Rossum, Manuel Reyes-Sánchez, Rodrigo Amaducci, Carlos Muñiz, Irene Elices, David Arroyo, Rafael Levi, Ben Cohen, Carson Chow, Shashaank Vattikuti, Elena Bertolotti, Raffaella Burioni, Matteo di Volo, Alessandro Vezzani, Bayar Menzat, Tim P. Vogels, Nobuhiko Wagatsuma, Susmita Saha, Reena Kapoor, Robert Kerr, John Wagner, Luis C. Garcia del Molino, Guangyu Robert Yang, Jorge F. Mejias, Xiao-Jing Wang, Hanbing Song, Joseph Goodliffe, Jennifer Luebke, Christina M. Weaver, John Thomas, Nishant Sinha, Nikhita Shaju, Tomasz Maszczyk, Jing Jin, Sydney S. Cash, Justin Dauwels, M. Brandon Westover, Maryam Karimian, Michelle Moerel, Peter De Weerd, Thomas Burwick, Ronald L. Westra, Romesh Abeysuriya, Jonathan Hadida, Stamatios Sotiropoulos, Saad Jbabdi, Mark Woolrich, Chama Bensmail, Borys Wrobel, Xiaolong Zhou, Zilong Ji, Xiao Liu, Yan Xia, Si Wu, Xiao Wang, Mingsha Zhang, Netanel Ofer, Orit Shefi, Gur Yaari, Ted Carnevale, Amit Majumdar, Subhashini Sivagnanam, Kenneth Yoshimoto, Elena Y. Smirnova, Dmitry V. Amakhin, Sergey L. Malkin, Aleksey V. Zaitsev, Anton V. Chizhov, Margarita Zaleshina, Alexander Zaleshin, Victor J. Barranca, George Zhu, Quinton M. Skilling, Daniel Maruyama, Nicolette Ognjanovski, Sara J. Aton, Michal Zochowski, Jiaxing Wu, Sara Aton, Scott Rich, Victoria Booth, Maral Budak, Salvador Dura-Bernal, Samuel A. Neymotin, Benjamin A. Suter, Gordon M. G. Shepherd, Melvin A. Felton, Alfred B. Yu, David L. Boothe, Kelvin S. Oie, Piotr J. Franaszczuk, Sergey A. Shuvaev, Batuhan Başerdem, Anthony Zador, Alexei A. Koulakov, Víctor J. López-Madrona, Ernesto Pereda, Claudio R. Mirasso, Santiago Canals, Stefano Masoli, Udaya B. Rongala, Anton Spanne, Henrik Jorntell, Calogero M. Oddo, Alexander V. Vartanov, Anastasia K. Neklyudova, Stanislav A. Kozlovskiy, Andrey A. Kiselnikov, Julia A. Marakshina, Maria Teleńczuk, Bartosz Teleńczuk, Alain Destexhe, Paula T. Kuokkanen, Anna Kraemer, Thomas McColgan, Catherine E. Carr, Richard Kempter

Publikováno v: BMC Neuroscience, Vol 18, Iss S1, Pp 1-82 (2017)

Externí odkaz: https://doaj.org/article/7aa2e239a0cc44ce9e290243885c7890

Sleep Promotes, and Sleep Loss Inhibits, Selective Changes in Firing Rate, Response Properties and Functional Connectivity of Primary Visual Cortex Neurons

Autor: Brittany C. Clawson, Jaclyn Durkin, Aneesha K. Suresh, Emily J. Pickup, Christopher G. Broussard, Sara J. Aton

Publikováno v: Frontiers in Systems Neuroscience, Vol 12 (2018)

Recent studies suggest that sleep differentially alters the activity of cortical neurons based on firing rates during preceding wake—increasing the firing rates of sparsely firing neurons and decreasing those of faster firing neurons. Because spars

Externí odkaz: https://doaj.org/article/225e51aad5134a6583de5eed5cc58837