Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Sara J Cooper"'
Autor:
Jun Wang, Holly R Thomas, Yu Chen, Stefanie M Percival, Stephanie C Waldrep, Ryne C Ramaker, Robert G Thompson, Sara J Cooper, Zechen Chong, John M Parant
Publikováno v:
PLoS Genetics, Vol 18, Iss 8, p e1010341 (2022)
Sister chromatid cohesion (SCC) is an important process in chromosome segregation. ESCO2 is essential for establishment of SCC and is often deleted/altered in human cancers. We demonstrate that esco2 haploinsufficiency results in reduced SCC and acce
Externí odkaz:
https://doaj.org/article/864da663a5114182a8a224d7246e376b
Autor:
Sarah E Williford, Catherine J Libby, Adetokunbo Ayokanmbi, Arphaxad Otamias, Juan J Gordillo, Emily R Gordon, Sara J Cooper, Matthew Redmann, Yanjie Li, Corinne Griguer, Jianhua Zhang, Marek Napierala, Subramaniam Ananthan, Anita B Hjelmeland
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0250649 (2021)
Treatment for the lethal primary adult brain tumor glioblastoma (GBM) includes the chemotherapy temozolomide (TMZ), but TMZ resistance is common and correlates with promoter methylation of the DNA repair enzyme O-6-methylguanine-DNA methyltransferase
Externí odkaz:
https://doaj.org/article/6f4edd46007d462793037386204079db
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 11, p e1006571 (2018)
Sequencing of the T cell receptor (TCR) repertoire is a powerful tool for deeper study of immune response, but the unique structure of this type of data makes its meaningful quantification challenging. We introduce a new method, the Gamma-GPD spliced
Externí odkaz:
https://doaj.org/article/3bc78e165aac4159b187898352f1a26b
Autor:
Pooja Ghatalia, Eddy S Yang, Brittany N Lasseigne, Ryne C Ramaker, Sara J Cooper, Dongquan Chen, Sunil Sudarshan, Shi Wei, Arjun S Guru, Amy Zhao, Tiffiny Cooper, Deborah L Della Manna, Gurudatta Naik, Richard M Myers, Guru Sonpavde
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160924 (2016)
Kinases are therapeutically actionable targets. Kinase inhibitors targeting vascular endothelial growth factor receptors (VEGFR) and mammalian target of rapamycin (mTOR) improve outcomes in metastatic clear cell renal cell carcinoma (ccRCC), but are
Externí odkaz:
https://doaj.org/article/4965e5d1648948e38899faaafc8f39cd
Autor:
Cyntanna C. Hawkins, Amber B. Jones, Emily R. Gordon, Yuvika Harsh, Julia K. Ziebro, Christopher D. Willey, Corinne Griguer, David K. Crossman, Sara J. Cooper, Sasanka Ramanadham, Ninh Doan, Anita B. Hjelmeland
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Sphingolipid metabolism is dysregulated in many cancers, allowing cells to evade apoptosis through increased sphingosine-1-phosphate (S1P) and decreased ceramides. Ceramidases hydrolyze ceramides to sphingosine, which is phosphorylated by sp
Externí odkaz:
https://doaj.org/article/968cfb928d054a14a0cfa5059517fa60
Autor:
Selene Meza-Perez, Troy D. Randall, Alexander F. Rosenberg, Rebecca C. Arend, Sara J. Cooper, Jennifer S. Pollock, Patrick A. Molina, Aaron Silva-Sanchez, Christopher D. Scharer, Dmytro Starenki, Mingyong Liu
Tumors that metastasize in the peritoneal cavity typically end up in the omental adipose tissue, a particularly immune-suppressive environment that includes specialized adipose-resident regulatory T cells (Treg). Tregs rapidly accumulate in the oment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103e6bd77aa9419821a41db44e630a07
https://doi.org/10.1158/2326-6066.c.6550593.v1
https://doi.org/10.1158/2326-6066.c.6550593.v1
Autor:
Selene Meza-Perez, Troy D. Randall, Alexander F. Rosenberg, Rebecca C. Arend, Sara J. Cooper, Jennifer S. Pollock, Patrick A. Molina, Aaron Silva-Sanchez, Christopher D. Scharer, Dmytro Starenki, Mingyong Liu
Supplementary Data from Circulating Tregs Accumulate in Omental Tumors and Acquire Adipose-Resident Features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a908612807761c770a359799199970f3
https://doi.org/10.1158/2326-6066.22544268
https://doi.org/10.1158/2326-6066.22544268
Autor:
Charles A. Leath, Charles N. Landen, Sara J. Cooper, David K. Crossman, Lea Novak, Jacob M. Estes, J. Michael Straughn, Kerri S. Bevis, Warner K. Huh, Ronald D. Alvarez, Eddy S. Yang, Alba Martinez, Ashwini A. Katre, Zachary C. Dobbin, Haller J. Smith, Allison M. Montgomery, Angelina I. Londoño, Rebecca C. Arend
Pathway and network analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573668f36f18590971fe8cf85fcbd99c
https://doi.org/10.1158/1541-7786.22515670
https://doi.org/10.1158/1541-7786.22515670
Autor:
Charles A. Leath, Charles N. Landen, Sara J. Cooper, David K. Crossman, Lea Novak, Jacob M. Estes, J. Michael Straughn, Kerri S. Bevis, Warner K. Huh, Ronald D. Alvarez, Eddy S. Yang, Alba Martinez, Ashwini A. Katre, Zachary C. Dobbin, Haller J. Smith, Allison M. Montgomery, Angelina I. Londoño, Rebecca C. Arend
Flowchart depicting the number of patients in each step of the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45b80ade58fd80649e385d263e4116ff
https://doi.org/10.1158/1541-7786.22515676
https://doi.org/10.1158/1541-7786.22515676
Autor:
Charles A. Leath, Charles N. Landen, Sara J. Cooper, David K. Crossman, Lea Novak, Jacob M. Estes, J. Michael Straughn, Kerri S. Bevis, Warner K. Huh, Ronald D. Alvarez, Eddy S. Yang, Alba Martinez, Ashwini A. Katre, Zachary C. Dobbin, Haller J. Smith, Allison M. Montgomery, Angelina I. Londoño, Rebecca C. Arend
R-plot PCA by cellularity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6811e4a74a1ef85bbba7cdf17e1fd2c
https://doi.org/10.1158/1541-7786.22515679.v1
https://doi.org/10.1158/1541-7786.22515679.v1