Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Sara J Brown"'
Autor:
Lucy E Bradshaw, Laura A Wyatt, Sara J Brown, Rachel H Haines, Alan A Montgomery, Michael R Perkin, Tracey H Sach, Sandra Lawton, Carsten Flohr, Matthew J Ridd, Joanne R Chalmers, Joanne Brooks, Richard Swinden, Eleanor J Mitchell, Stella Tarr, Nicola Jay, Kim S Thomas, Hilary Allen, Michael J Cork, Maeve M Kelleher, Eric L Simpson, Stella T Lartey, Susan Davies-Jones, Robert J Boyle, Hywel C Williams
Publikováno v:
Health Technology Assessment, Vol 28, Iss 29 (2024)
Background Atopic eczema is a common childhood skin problem linked with asthma, food allergy and allergic rhinitis that impairs quality of life. Objectives To determine whether advising parents to apply daily emollients in the first year can prevent
Externí odkaz:
https://doaj.org/article/e5d9259b3c9a4a81b766b775b673c2bb
Autor:
Ashley Budu-Aggrey, Ben Brumpton, Jess Tyrrell, Sarah Watkins, Ellen H Modalsli, Carlos Celis-Morales, Lyn D Ferguson, Gunnhild Åberge Vie, Tom Palmer, Lars G Fritsche, Mari Løset, Jonas Bille Nielsen, Wei Zhou, Lam C Tsoi, Andrew R Wood, Samuel E Jones, Robin Beaumont, Marit Saunes, Pål Richard Romundstad, Stefan Siebert, Iain B McInnes, James T Elder, George Davey Smith, Timothy M Frayling, Bjørn Olav Åsvold, Sara J Brown, Naveed Sattar, Lavinia Paternoster
Publikováno v:
PLoS Medicine, Vol 16, Iss 1, p e1002739 (2019)
BackgroundPsoriasis is a common inflammatory skin disease that has been reported to be associated with obesity. We aimed to investigate a possible causal relationship between body mass index (BMI) and psoriasis.Methods and findingsFollowing a review
Externí odkaz:
https://doaj.org/article/f74e86d2e0074e57ac87d4c412e76f84
Autor:
Kim S Thomas, Lucy E Bradshaw, Tracey H Sach, Jonathan M Batchelor, Sandra Lawton, Eleanor F Harrison, Rachel H Haines, Amina Ahmed, Hywel C Williams, Taraneh Dean, Nigel P Burrows, Ian Pollock, Joanne Llewellyn, Clare Crang, Jane D Grundy, Juliet Guiness, Andrew Gribbin, Eleanor J Mitchell, Fiona Cowdell, Sara J Brown, Alan A Montgomery, UK Dermatology Clinical Trials Network’s CLOTHES Trial Team
Publikováno v:
PLoS Medicine, Vol 14, Iss 4, p e1002280 (2017)
BackgroundThe role of clothing in the management of eczema (also called atopic dermatitis or atopic eczema) is poorly understood. This trial evaluated the effectiveness and cost-effectiveness of silk garments (in addition to standard care) for the ma
Externí odkaz:
https://doaj.org/article/0cb97fd228864e2da5a26383c0ddfa07
Autor:
Kim S Thomas, Lucy E Bradshaw, Tracey H Sach, Fiona Cowdell, Jonathan M Batchelor, Sandra Lawton, Eleanor F Harrison, Rachel H Haines, Amina Ahmed, Taraneh Dean, Nigel P Burrows, Ian Pollock, Hannah K Buckley, Hywel C Williams, Joanne Llewellyn, Clare Crang, Jane D Grundy, Juliet Guiness, Andrew Gribbin, Eileen V Wake, Eleanor J Mitchell, Sara J Brown, Alan A Montgomery
Publikováno v:
Health Technology Assessment, Vol 21, Iss 16 (2017)
Background: Atopic eczema (AE) is a chronic, itchy, inflammatory skin condition that affects the quality of life of children and their families. The role of specialist clothing in the management of AE is poorly understood. Objectives: To assess the e
Externí odkaz:
https://doaj.org/article/ae35f97225b24d7db81cf4439af20d15
Autor:
Nicholas J Schurch, Christian Cole, Alexander Sherstnev, Junfang Song, Céline Duc, Kate G Storey, W H Irwin McLean, Sara J Brown, Gordon G Simpson, Geoffrey J Barton
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94270 (2014)
The reference annotations made for a genome sequence provide the framework for all subsequent analyses of the genome. Correct and complete annotation in addition to the underlying genomic sequence is particularly important when interpreting the resul
Externí odkaz:
https://doaj.org/article/34addfaf11e64ceba92df6606549372e
Autor:
Lucy E. Bradshaw, Laura A. Wyatt, Sara J. Brown, Rachel H. Haines, Alan A. Montgomery, Michael R. Perkin, Sandra Lawton, Tracey H. Sach, Joanne R. Chalmers, Matthew J. Ridd, Carsten Flohr, Joanne Brooks, Richard Swinden, Eleanor J. Mitchell, Stella Tarr, Nicola Jay, Kim S. Thomas, Hilary Allen, Michael J. Cork, Maeve M. Kelleher, Eric L. Simpson, Stella T. Lartey, Susan Davies‐Jones, Robert J. Boyle, Hywel C. Williams
Publikováno v:
Allergy. 78:995-1006
Background: The effectiveness of emollients for preventing atopic dermatitis/eczema is controversial. The Barrier Enhancement for Eczema Prevention trial evaluated the effects of daily emollients during the first year of life on atopic dermatitis and
Autor:
Martina S. Elias, Sheila C. Wright, William V. Nicholson, Kimberley D. Morrison, Alan R. Prescott, Sara Ten Have, Phillip D. Whitfield, Angus I. Lamond, Sara J. Brown
Publikováno v:
Wellcome Open Research, Vol 4 (2019)
Background: Atopic eczema is an itchy inflammatory disorder characterised by skin barrier dysfunction. Loss-of-function mutations in the gene encoding filaggrin (FLG) are a major risk factor, but the mechanisms by which filaggrin haploinsufficiency l
Externí odkaz:
https://doaj.org/article/14616f7f675c4e30b80ba40a1401b765
Autor:
Argho A. Paul, Natalia Szulc, Adrian Kobiela, Sara J. Brown, Wojciech Pokrzywa, Danuta Gutowska-Owsiak
Publikováno v:
Frontiers in Molecular Biosciences. 10
Background: Loss of function mutation in FLG is the major genetic risk factor for atopic dermatitis (AD) and other allergic manifestations. Presently, little is known about the cellular turnover and stability of profilaggrin, the protein encoded by F
Autor:
Joanne R. Chalmers, Rachel H. Haines, Eleanor J. Mitchell, Kim S. Thomas, Sara J. Brown, Matthew Ridd, Sandra Lawton, Eric L. Simpson, Michael J. Cork, Tracey H. Sach, Lucy E. Bradshaw, Alan A. Montgomery, Robert J. Boyle, Hywel C. Williams
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-11 (2017)
Abstract Background Atopic eczema (AE) is a common skin problem that impairs quality of life and is associated with the development of other atopic diseases including asthma, food allergy and allergic rhinitis. AE treatment is a significant cost burd
Externí odkaz:
https://doaj.org/article/6cf16ca91ee0430f9304d01c1a6f9e32
Publikováno v:
Journal of Investigative Dermatology. 141:2761-2764