Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Sara I. Pai"'
Autor:
Rong Li, Francois Ghiringhelli, Antoine Italiano, Antoni Ribas, Paolo Antonio Ascierto, Michael Cecchini, Joseph Paul Eder, Kurt A Schalper, Sara I Pai, Mace Rothenberg, Ellen Pure, Wolf Herve Fridman, Fatima Mechta-Grigoriou, Guy Travis Clifton, Glenn Begley, Marina Kochetkova, Paolo Provenzano
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Checkpoint inhibitors represent an effective treatment approach for a variety of cancers through their inhibition of immune regulatory pathways within the tumor microenvironment (TME). Unfortunately only a minority of patients with cancer achieve cli
Externí odkaz:
https://doaj.org/article/3536fd9b7adb4dc68227628c4f9989e9
Autor:
Ruben Bill, Daniel G. Deschler, Mikael J. Pittet, Sara I. Pai, Peter M. Sadow, Jong Chul Park
Publikováno v:
Cancer Reports, Vol 5, Iss 3, Pp n/a-n/a (2022)
Abstract Background Secretory carcinoma is a more recently described subtype of salivary gland carcinoma that may pose diagnostic challenges and frequently harbors NTRK fusions that may successfully be targeted by TRK inhibitors in advanced disease.
Externí odkaz:
https://doaj.org/article/3502dd3b3d334ee6b7ccb156233cf336
Autor:
Sara I. Pai, Ezra E. W. Cohen, Derrick Lin, George Fountzilas, Edward S. Kim, Holger Mehlhorn, Neus Baste, Daniel Clayburgh, Loren Lipworth, Carlo Resteghini, Nawar Shara, Takashi Fujii, Jun Zhang, Michael Stokes, Huifen Wang, Philip Twumasi-Ankrah, Sophie Wildsmith, Asud Khaliq, Giovanni Melillo, Norah Shire
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-14 (2019)
Abstract Background Programmed cell death ligand-1 (PD-L1) expression on tumor cells (TCs) is associated with improved survival in patients with head and neck squamous cell carcinoma (HNSCC) treated with immunotherapy, although its role as a prognost
Externí odkaz:
https://doaj.org/article/a6cc8d6715dd481d84183933b4c912f5
Autor:
Sara I. Pai, Sandrine Faivre, Lisa Licitra, Jean-Pascal Machiels, Jan B. Vermorken, Paolo Bruzzi, Viktor Gruenwald, Raul E. Giglio, C. René Leemans, Tanguy Y. Seiwert, Denis Soulieres
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-4 (2019)
Abstract Two phase III clinical trials (CheckMate 141 and KEYNOTE 040) have independently demonstrated that overall survival (OS) in recurrent and/or metastatic head and neck squamous cell carcinoma (R/M HNSCC) patients, who have failed platinum-base
Externí odkaz:
https://doaj.org/article/f0b003406a0943e7b05d2212424c9c8d
Publikováno v:
The Lancet Healthy Longevity. 4:e166-e175
Autor:
Yi Sun, Or-yam Revach, Seth Anderson, Emily A. Kessler, Clara H. Wolfe, Anne Jenney, Caitlin E. Mills, Emily J. Robitschek, Thomas G. R. Davis, Sarah Kim, Amina Fu, Xiang Ma, Jia Gwee, Payal Tiwari, Peter P. Du, Princy Sindurakar, Jun Tian, Arnav Mehta, Alexis M. Schneider, Keren Yizhak, Moshe Sade-Feldman, Thomas LaSalle, Tatyana Sharova, Hongyan Xie, Shuming Liu, William A. Michaud, Rodrigo Saad-Beretta, Kathleen B. Yates, Arvin Iracheta-Vellve, Johan K. E. Spetz, Xingping Qin, Kristopher A. Sarosiek, Gao Zhang, Jong Wook Kim, Mack Y. Su, Angelina M. Cicerchia, Martin Q. Rasmussen, Samuel J. Klempner, Dejan Juric, Sara I. Pai, David M. Miller, Anita Giobbie-Hurder, Jonathan H. Chen, Karin Pelka, Dennie T. Frederick, Susanna Stinson, Elena Ivanova, Amir R. Aref, Cloud P. Paweletz, David A. Barbie, Debattama R. Sen, David E. Fisher, Ryan B. Corcoran, Nir Hacohen, Peter K. Sorger, Keith T. Flaherty, Genevieve M. Boland, Robert T. Manguso, Russell W. Jenkins
Publikováno v:
Nature. 615:158-167
Autor:
Howard L Kaufman, Steven A Rosenberg, Adekunle Odunsi, Pranav Murthy, Piyush K Agarwal, Stephen Broderick, Peter E Fecci, Stephanie L Goff, Matthew M Grabowski, Rogerio I Neves, Sara I Pai, Sangeetha Prabhakaran, Ragheed Saoud, Joseph Skitzki, John B Sunwoo, Cecilia CS Yeung
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Immunotherapy is now a cornerstone for cancer treatment, and much attention has been placed on the identification of prognostic and predictive biomarkers. The success of biomarker development is dependent on accurate and timely collection of biospeci
Externí odkaz:
https://doaj.org/article/20db5803d1fa467cab907b6e8216be86
Autor:
Vinay K. Kartha, Khalid A. Alamoud, Khikmet Sadykov, Bach-Cuc Nguyen, Fabrice Laroche, Hui Feng, Jina Lee, Sara I. Pai, Xaralabos Varelas, Ann Marie Egloff, Jennifer E. Snyder-Cappione, Anna C. Belkina, Manish V. Bais, Stefano Monti, Maria A. Kukuruzinska
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-18 (2018)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) is an aggressive malignancy characterized by tumor heterogeneity, locoregional metastases, and resistance to existing treatments. Although a number of genomic and molecular alterations
Externí odkaz:
https://doaj.org/article/3f10be2b6404420f97878bd8174c79b8
Autor:
Sara I, Pai, Isaac, Wasserman, Yisi D, Ji, Matthew, Gilman, Yin P, Hung, William C, Faquin, Mari, Mino-Kenudson, Ashok, Muniappan
Publikováno v:
The Lancet Respiratory Medicine. 10:997-1008
Human papillomavirus (HPV) types 6 and 11 can infect the squamous epithelium of the respiratory tract. Up to 8·9% of patients with HPV-associated recurrent respiratory papillomatosis (RRP) have pulmonary involvement. Pulmonary manifestations of HPV
Autor:
Joao L.G.C. Monteiro, Toru Takusagawa, Belmiro C.E. Vasconcelos, Sara I. Pai, Joseph P. McCain, Fernando P.S. Guastaldi
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 134:20-27
The objective of this study was 2-fold: (1) to describe the rabbit temporomandibular joint (TMJ) anatomy and (2) to provide a detailed, step-by-step description of a minimally invasive approach to perform a standard osteochondral TMJ defect that can