Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sara Hijazi"'
Publikováno v:
Sensors and Actuators Reports, Vol 5, Iss , Pp 100158- (2023)
A screen-printed carbon electrode was used to develop a biosensor with an improved response and selectivity for detecting human epidermal growth factor receptor 2 (HER2). To investigate the performance of the biosensor, electrochemical characterizati
Externí odkaz:
https://doaj.org/article/a6332d16765e4a13bd18a9482bc062fb
Autor:
Sara Hijazi, Tim S. Heistek, Rolinka van der Loo, Huibert D. Mansvelder, August B. Smit, Ronald E. van Kesteren
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101271- (2020)
Summary: Parvalbumin (PV) interneuron dysfunction is associated with various brain disorders, including Alzheimer disease (AD). Here, we asked whether early PV neuron hyperexcitability primes the hippocampus for amyloid beta-induced functional impair
Externí odkaz:
https://doaj.org/article/fa1b308823a54f35a4babee6a6085298
Autor:
Sara Hijazi, Samir Emam
Publikováno v:
Composite Structures. 312:116880
Autor:
Tim S. Heistek, Sara Hijazi, Philip Scheltens, Derya R. Shimshek, August B. Smit, Ulf Neumann, Ronald E. van Kesteren, Huibert D. Mansvelder
Publikováno v:
Molecular Psychiatry, 25(12), 3380-3398. Nature Publishing Group
Molecular Psychiatry
Hijazi, S, Heistek, T S, Scheltens, P, Neumann, U, Shimshek, D R, Mansvelder, H D, Smit, A B & van Kesteren, R E 2020, ' Early restoration of parvalbumin interneuron activity prevents memory loss and network hyperexcitability in a mouse model of Alzheimer’s disease ', Molecular Psychiatry, vol. 25, no. 12, pp. 3380-3398 . https://doi.org/10.1038/s41380-019-0483-4
Molecular Psychiatry
Hijazi, S, Heistek, T S, Scheltens, P, Neumann, U, Shimshek, D R, Mansvelder, H D, Smit, A B & van Kesteren, R E 2020, ' Early restoration of parvalbumin interneuron activity prevents memory loss and network hyperexcitability in a mouse model of Alzheimer’s disease ', Molecular Psychiatry, vol. 25, no. 12, pp. 3380-3398 . https://doi.org/10.1038/s41380-019-0483-4
Neuronal network dysfunction is increasingly recognized as an early symptom in Alzheimer’s disease (AD) and may provide new entry points for diagnosis and intervention. Here, we show that amyloid-beta-induced hyperexcitability of hippocampal inhibi
Autor:
Ronald E. van Kesteren, Sara Hijazi, Rolinka J. van der Loo, Huibert D. Mansvelder, Tim S. Heistek, August B. Smit
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101271-(2020)
iScience, 23(7):101271, 1-25. Elsevier
iScience
Hijazi, S, Heistek, T S, van der Loo, R, Mansvelder, H D, Smit, A B & van Kesteren, R E 2020, ' Hyperexcitable Parvalbumin Interneurons Render Hippocampal Circuitry Vulnerable to Amyloid Beta ', iScience, vol. 23, no. 7, 101271, pp. 1-25 . https://doi.org/10.1016/j.isci.2020.101271
iScience, 23(7):101271, 1-25. Elsevier
iScience
Hijazi, S, Heistek, T S, van der Loo, R, Mansvelder, H D, Smit, A B & van Kesteren, R E 2020, ' Hyperexcitable Parvalbumin Interneurons Render Hippocampal Circuitry Vulnerable to Amyloid Beta ', iScience, vol. 23, no. 7, 101271, pp. 1-25 . https://doi.org/10.1016/j.isci.2020.101271
Summary Parvalbumin (PV) interneuron dysfunction is associated with various brain disorders, including Alzheimer disease (AD). Here, we asked whether early PV neuron hyperexcitability primes the hippocampus for amyloid beta-induced functional impairm
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Tim S. Heistek, Sara Hijazi, Philip Scheltens, Ronald E. van Kesteren, August B. Smit, Huibert D. Mansvelder
Publikováno v:
Alzheimer's & Dementia. 16
Autor:
Ka Wan Li, Arie J Timmerman, Willem Kamphuis, Céline M. Heldring, Pim van Nierop, August B. Smit, Sara Hijazi, Elly M. Hol, Marlene J. Végh, Huibert D. Mansvelder, Ronald E. van Kesteren
Publikováno v:
Acta neuropathologica communications, 2. BioMed Central
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Alzheimer’s disease is caused by increased production or reduced clearance of amyloid-β, which results in the formation amyloid-β plaques and triggers a cascade of downstream events leading to progressive neurodegeneration. The earliest clinical