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Clonal Changes in the Pneumococcal Population Carried by Portuguese Children during Six Years of Private Use of the 13-Valent Pneumococcal Conjugate Vaccine: the Relative Contribution of Clonal Expansion, Clonal Emergence, and Capsular Switch Events

Autor: Catarina Candeias, Sofia Félix, Sara Handem, Hermínia de Lencastre, Raquel Sá-Leão

Publikováno v: Microbiology Spectrum. 11

Streptococcus pneumoniae (pneumococcus) is a major human respiratory pathogen linked with high morbidity, mortality, and health care-associated costs worldwide. This bacterium often colonizes asymptomatically healthy children.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a0dccc58578f08b48632f825a4a021ae
https://doi.org/10.1128/spectrum.02909-22

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Impact of private use of the 13-valent pneumococcal conjugate vaccine (PCV13) on pneumococcal carriage among Portuguese children living in urban and rural regions

Autor: Sofia Félix, Raquel Sá-Leão, Sónia Nunes, Sónia T. Almeida, António Brito-Avô, Ana Cristina Paulo, Hermínia de Lencastre, Carina Valente, Sara Handem, Alexandra S. Simões, Débora A. Tavares, Catarina Candeias

Publikováno v: Vaccine. 39(32)

In Portugal, the 13-valent pneumococcal conjugate vaccine (PCV13) was commercially available between 2010 and 2015, following a decade of private use of PCV7. We evaluated changes on serotype distribution and antimicrobial susceptibility of pneumococ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf955921d1f0160dd9bbd7fc49b4639
https://pubmed.ncbi.nlm.nih.gov/34183206

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Identification of Streptococcus pneumoniae by a real-time PCR assay targeting SP2020

Autor: Raquel Sá-Leão, Sara Handem, A. Cristina Paulo, Ricardo J. Carvalho, Jason Hinds, Hermínia de Lencastre, Débora A. Tavares

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

Real-time PCR targeting lytA (the major autolysin gene) and piaB (permease gene of the pia ABC transporter) are currently used as the gold-standard culture-independent assays for Streptococcus pneumoniae identification. We evaluated the performance o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301c8fef9fb897cc2a167ed135c5d626
https://openaccess.sgul.ac.uk/id/eprint/110747/1/s41598-019-39791-1.pdf

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Akademický článek

Identification of Streptococcus pneumoniae by a real-time PCR assay targeting SP2020.

Autor: Tavares, Débora A.¹, Handem, Sara¹, Carvalho, Ricardo J.¹, Paulo, A. Cristina¹, de Lencastre, Hermínia^2,3, Hinds, Jason⁴, Sá-Leão, Raquel^1,5 rsaleao@itqb.unl.pt

Publikováno v: Scientific Reports. 3/1/2019, Vol. 9 Issue 1, p1-1. 1p.

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Periodical

NOVA University Lisbon Reports Findings in Conjugate Vaccines (Clonal Changes in the Pneumococcal Population Carried by Portuguese Children during Six Years of Private Use of the 13-Valent Pneumococcal Conjugate Vaccine: the Relative...).

Publikováno v: Pediatrics Week; 4/7/2023, p287-287, 1p

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