Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sara H. Hazem"'
Autor:
Rasha Abdelhady, Sameh Saber, Mustafa Ahmed Abdel-Reheim, Mohannad Mohammad S. Alamri, Jaber Alfaifi, Masoud I. E. Adam, Lobna A. Saleh, Azza I. Farag, Elsayed A. Elmorsy, Hend S. El-Wakeel, Ahmed S. Doghish, Mohamed E. Shaker, Sara H. Hazem, Heba A. Ramadan, Rabab S. Hamad, Osama A. Mohammed
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/47a8bdc561b643be8c678472eeb3e4d3
Autor:
Rasha Abdelhady, Sameh Saber, Mustafa Ahmed Abdel-Reheim, Mohannad Mohammad S. Alamri, Jaber Alfaifi, Masoud I. E. Adam, Lobna A. Saleh, Azza I. Farag, Elsayed A. Elmorsy, Hend S. El-Wakeel, Ahmed S. Doghish, Mohamed E. Shaker, Sara H. Hazem, Heba A. Ramadan, Rabab S. Hamad, Osama A. Mohammed
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Ulcerative colitis (UC) is a chronic relapsing inflammatory disease of the colorectal area that demonstrates a dramatically increasing incidence worldwide. This study provides novel insights into the capacity of the exogenous β-hydroxybutyrate and k
Externí odkaz:
https://doaj.org/article/963d754da07e445b9102ebb7075ec431
Autor:
Mohamed E. Shaker, Hesham A. M. Gomaa, Sara H. Hazem, Mohamed A. Abdelgawad, Mohamed El-Mesery, Ahmed A. Shaaban
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/79ebe987326047009e88ba6cc2d179bd
Autor:
Mohamed E. Shaker, Hesham A. M. Gomaa, Sara H. Hazem, Mohamed A. Abdelgawad, Mohamed El-Mesery, Ahmed A. Shaaban
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The sterile inflammatory response mediated by Toll-like receptors (TLRs) 4 and 9 is implicated in the massive hepatic damage caused by acetaminophen (APAP)-overdose. There is a crosstalk between TLR-dependent signaling with other intracellular kinase
Externí odkaz:
https://doaj.org/article/7b33e56f892e467d8c3a98d0e36eeda3
Autor:
Osama A. Mohammed, Mustafa Ahmed Abdel-Reheim, Mohannad Mohammad S. Alamri, Jaber Alfaifi, Masoud I. E. Adam, Lobna A. Saleh, Alshaimaa A. Farrag, Amar Ibrahim Omer Yahia, Sameh Abdel-Ghany, AbdulElah Al Jarallah AlQahtani, Emad Bahashwan, Hanan B. Eltahir, Nahid A. Mohammed, Hend S. El-wakeel, Sara H. Hazem, Sameh Saber
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1080 (2023)
Liver fibrosis is a progressive condition characterized by the build-up of fibrous tissue resulting from long-term liver injury. Although there have been advancements in research and treatment, there is still a need for effective antifibrotic medicat
Externí odkaz:
https://doaj.org/article/84327d2d07984187a33d8f5a52f65357
Autor:
Mohamed E. Shaker, Hesham A.M. Gomaa, Khalid S. Alharbi, Mohammad M. Al-Sanea, Mohamed E. El-Mesery, Sara H. Hazem
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 131, Iss , Pp 110736- (2020)
Bruton tyrosine kinase (BTK) sits at the crossroads of adaptive and innate immunities. Nevertheless, the detailed role of BTK activation in hepatic inflammatory disorders is still elusive to date. Accordingly, we investigated the impact of blocking B
Externí odkaz:
https://doaj.org/article/ba5723220b6c45738999d7763519b27d
Autor:
Mohamed E. Shaker, Hesham A.M. Gomaa, Mohamed A. Abdelgawad, Mohamed El-Mesery, Ahmed A. Shaaban, Sara H. Hazem
Publikováno v:
International Immunopharmacology. 120:110373
Publikováno v:
International Immunopharmacology. 103:108463
Therapeutics that impair the innate immune responses of the liver during the inflammatory cytokine storm like that occurring in COVID-19 are greatly needed. Much interest is currently directed toward Janus kinase (JAK) inhibitors as potential candida
Autor:
Mohamed El-Mesery, Mohamed E. Shaker, Mohammad M. Al-Sanea, Khalid Saad Alharbi, Sara H. Hazem, Hesham A.M. Gomaa
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 131, Iss, Pp 110736-(2020)
Bruton tyrosine kinase (BTK) sits at the crossroads of adaptive and innate immunities. Nevertheless, the detailed role of BTK activation in hepatic inflammatory disorders is still elusive to date. Accordingly, we investigated the impact of blocking B
Publikováno v:
Food and Chemical Toxicology. 96:290-301
In an attempt to explore the role of the JAK/STAT pathway in liver inflammation, we investigated the effect of intervening this pathway by ruxolitinib in thioacetamide (TAA)-induced hepatotoxicity. Ruxolitinib treatments were administered to male mic