Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sara Guariento"'
Autor:
Sara Guariento, Silvia Franchini, Michele Tonelli, Paola Fossa, Claudia Sorbi, Elena Cichero, Livio Brasili
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 214-230 (2017)
The 5-hydroxytryptamine (5-HT1A) receptors represent an attractive target in drug discovery. In particular, 5-HT1A agonists and partial agonists are deeply investigated for their potential role in the treatment of anxiety, depression, ischaemic brain
Externí odkaz:
https://doaj.org/article/6b7bb9906c81442d9059067a45053d12
Autor:
Dr. Antonio Del Vecchio, Elisabetta Rosadoni, Lorenzo Ballerini, Dr. Angela Cuzzola, Prof. Filippo Lipparini, Dr. Paolo Ronchi, Dr. Sara Guariento, Dr. Matteo Biagetti, Prof. Marco Lessi, Prof. Fabio Bellina
Publikováno v:
ChemistryOpen, Vol 13, Iss 11, Pp n/a-n/a (2024)
Abstract A selective direct arylation of the different Csp2‐H bonds of imidazo[2,1‐b]thiazole with (hetero) aryl halides can be achieved simply by switching from a palladium catalyst system to the use of stoichiometric amounts of copper. The obse
Externí odkaz:
https://doaj.org/article/7eabd614b0fc4753bc1c3be67f640666
Autor:
Sara Guariento, Mattia Chesi, Fabio Bellina, Diego Copelli, Luca Venturi, Emanuela Bua, Elisa Moretti, Paolo Ronchi
Publikováno v:
ChemistrySelect. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79f91b3917737dbdbfad7682ce0df313
https://doi.org/10.1002/slct.202203916
https://doi.org/10.1002/slct.202203916
Autor:
Matteo Biagetti, Veronica Nigroni, Paolo Bruno, Daniele Pala, Daniela Pizzirani, Sara Guariento, Paolo Ronchi, Claudio Fiorelli
Publikováno v:
Current Organic Chemistry. 25:2089-2115
The use of F-based decorations in drug discovery started from the development of fluorocorticoids and fluorochinolones (1950s and 1980s respectively) and it resulted in about 20% of approved drugs on the Market containing fluorine. From a medicinal c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c9c1633a64362c81a67b93a8d780492
https://doi.org/10.2174/1385272825666210706130210
https://doi.org/10.2174/1385272825666210706130210
Autor:
Matteo Biagetti, Fabio Bellina, Elisabetta Rosadoni, Marco Lessi, Mattia Fausti, Sara Guariento, Paolo Ronchi
Publikováno v:
RSC Advances. 11:25504-25509
A variety of 2-alkynyl(benzo)imidazoles have been synthesized by dehydrogenative alkynylation of (benzo)imidazoles with terminal alkyne in NMP under air in the presence of Ag2CO3 as the oxidant and Pd(OAc)2 as the catalyst precursor. The data obtaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af59722674e2abcd60b44c09f55e35ff
https://doi.org/10.1039/d1ra05303e
https://doi.org/10.1039/d1ra05303e
Publikováno v:
Future medicinal chemistry. 13(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c20090e4785ff76dfaae3eb02fde6f5b
https://pubmed.ncbi.nlm.nih.gov/33657835
https://pubmed.ncbi.nlm.nih.gov/33657835
Autor:
Michele Tonelli, Livio Brasili, Paola Fossa, Sara Guariento, Claudia Sorbi, Silvia Franchini, Elena Cichero
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 214-230 (2017)
The 5-hydroxytryptamine (5-HT1A) receptors represent an attractive target in drug discovery. In particular, 5-HT1A agonists and partial agonists are deeply investigated for their potential role in the treatment of anxiety, depression, ischaemic brain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e44ebbfc921c24e97a20f2a80b1a5f
https://doaj.org/article/6b7bb9906c81442d9059067a45053d12
https://doaj.org/article/6b7bb9906c81442d9059067a45053d12
Autor:
Michele Tonelli, Raul R. Gainetdinov, Stefano Espinoza, Elena Cichero, Sara Guariento, Andrey S. Gerasimov
The design of novel chemical classes acting towards several G-protein-coupled receptors (GPCRs) represents a leading strategy in drug discovery, aimed at deriving effective and safe candidates for further assessment. During the last years, TAAR1 aros
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094b0c833577edf693892a06860393fa
http://hdl.handle.net/11567/888486
http://hdl.handle.net/11567/888486
Publikováno v:
Molecular Diversity. 20:77-92
PDE4 inhibitors have been largely studied because of their promising therapeutic effects concerning inflammation and neurodegenerative dysfunctions, such as depression, schizophrenia and Alzheimer's diseases. In this context, the PDE4B isoform proved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd22a46c4223e758ed6d7e90b211808d
https://doi.org/10.1007/s11030-015-9631-1
https://doi.org/10.1007/s11030-015-9631-1
Publikováno v:
MedChemComm. 6:1978-1986
CB1 and CB2 receptors belong to the large family of G-protein coupled receptors (GPCRs), being involved in a wide variety of signal transduction processes. In this context, CB2 selective compounds were described in the literature to be active in diff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bfc2c9a4bfcbcb851c0070615a2a0cd
https://doi.org/10.1039/c5md00333d
https://doi.org/10.1039/c5md00333d