Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sara Grove"'
Autor:
Jae Eun Choi, Yuanyuan Qiao, Ilona Kryczek, Jiali Yu, Jonathan Gurkan, Yi Bao, Mahnoor Gondal, Jean Ching-Yi Tien, Tomasz Maj, Sahr Yazdani, Abhijit Parolia, Houjun Xia, JiaJia Zhou, Shuang Wei, Sara Grove, Linda Vatan, Heng Lin, Gaopeng Li, Yang Zheng, Yuping Zhang, Xuhong Cao, Fengyun Su, Rui Wang, Tongchen He, Marcin Cieslik, Michael D. Green, Weiping Zou, Arul M. Chinnaiyan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cancer treatment continues to shift from utilizing traditional therapies to targeted ones, such as protein kinase inhibitors and immunotherapy. Mobilizing dendritic cells (DC) and other myeloid cells with antigen presenting and cancer cell k
Externí odkaz:
https://doaj.org/article/110a46dd843f458b99af5d4a3c335b08
Autor:
Danfeng Sun, Weichao Wang, Fangfang Guo, Michael R. Pitter, Wan Du, Shuang Wei, Sara Grove, Linda Vatan, Yingxuan Chen, Ilona Kryczek, Eric R. Fearon, Jing-Yuan Fang, Weiping Zou
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Chronic inflammation and oncogenic pathway activation are key-contributing factors in colorectal cancer pathogenesis. However, colorectal intrinsic mechanisms linking these two factors in cancer development are poorly defined. Here, we show that inte
Externí odkaz:
https://doaj.org/article/b15ed1fa7f02475197f41ee424609607
Autor:
Houjun Xia, Shasha Li, Xiong Li, Weichao Wang, Yingjie Bian, Shuang Wei, Sara Grove, Weimin Wang, Linda Vatan, J. Rebecca Liu, Karen McLean, Ramandeep Rattan, Adnan Munkarah, Jun-Lin Guan, Ilona Kryczek, Weiping Zou
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
Tumor-associated macrophages (TAMs) affect cancer progression and therapy. Ovarian carcinoma often metastasizes to the peritoneal cavity. Here, we found 2 peritoneal macrophage subsets in mice bearing ID8 ovarian cancer based on T cell immunoglobulin
Externí odkaz:
https://doaj.org/article/6c9048172d6640499478c9301ae55769
Autor:
Weiping Zou, Jing-Yuan Fang, Ilona Kryczek, Haoyan Chen, Grzegorz Wallner, Marek Majewski, Witold Zgodziński, Linda Vatan, Sara Grove, Shuang Wei, Gaopeng Li, Yijian Yan, Peng Liao, Weimin Wang, Jiajia Zhou, Weichao Wang, Shasha Li, Jian Zhang, Xiong Li, Fang Hua, Wan Du
Supplementary Figure S1-9 and Supplementary Tables S1-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92274e513c323e5adda02a029a22aa46
https://doi.org/10.1158/2159-8290.22540280.v1
https://doi.org/10.1158/2159-8290.22540280.v1
Autor:
Weiping Zou, Jing-Yuan Fang, Ilona Kryczek, Haoyan Chen, Grzegorz Wallner, Marek Majewski, Witold Zgodziński, Linda Vatan, Sara Grove, Shuang Wei, Gaopeng Li, Yijian Yan, Peng Liao, Weimin Wang, Jiajia Zhou, Weichao Wang, Shasha Li, Jian Zhang, Xiong Li, Fang Hua, Wan Du
Mutations in IFN and MHC signaling genes endow immunotherapy resistance. Patients with colorectal cancer infrequently exhibit IFN and MHC signaling gene mutations and are generally resistant to immunotherapy. In exploring the integrity of IFN and MHC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e53f27c74333b3e50384590815ff6de
https://doi.org/10.1158/2159-8290.c.6549344.v1
https://doi.org/10.1158/2159-8290.c.6549344.v1
Autor:
Jutaek Nam, Ilona Kryczek, Heng Lin, Chitra Subramanian, James J. Moon, Jing Li, Shuang Wei, Wan Du, Sara Grove, Gaopeng Li, Ton Wang, Mark S. Cohen, Jiajia Zhou, Weiping Zou, Linda Vatan, Marcin Cieslik, Shasha Li, Xiong Li
Publikováno v:
Nature cell biology
Major histocompatibility complex-I (MHC-I) presents tumour antigens to CD8+ T cells and triggers anti-tumour immunity. Humans may have 30,000–60,000 long noncoding RNAs (lncRNAs). However, it remains poorly understood whether lncRNAs affect tumour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caec6c56a6c690172b3cdb1a7a69d02b
https://doi.org/10.1038/s41556-021-00672-3
https://doi.org/10.1038/s41556-021-00672-3
Autor:
Linda Vatan, Weichao Wang, Angelo Aguilar, Shasha Li, Sara Grove, Xueting Lang, Shaomeng Wang, Jing Li, Ilona Kryczek, Peng Liao, Jiajia Zhou, Yijian Yan, Weimin Wang, Wan Du, Shuang Wei, Gaopeng Li, Weiping Zou, Xiong Li, Jiali Yu, Heng Lin
Publikováno v:
Nature immunology
Targeting the p53-MDM2 pathway to reactivate tumor p53 is a chemotherapeutic approach. However, the involvement of this pathway in CD8+ T cell-mediated antitumor immunity is unknown. Here, we report that mice with MDM2 deficiency in T cells exhibit a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2b996c3d78cc2d3f4a1ce7c9952cdd
https://doi.org/10.1038/s41590-021-00888-3
https://doi.org/10.1038/s41590-021-00888-3
Autor:
Linda Vatan, Weiping Zou, Yijian Yan, Weichao Wang, Gaopeng Li, Xiong Li, Jiajia Zhou, Shuang Wei, Grzegorz Wallner, Weimin Wang, Marek Majewski, Wan Du, Jian Zhang, Shasha Li, Sara Grove, Haoyan Chen, Fang Hua, Witold Zgodziński, Jing-Yuan Fang, Peng Liao, Ilona Kryczek
Publikováno v:
Cancer Discovery. 11:1826-1843
Mutations in IFN and MHC signaling genes endow immunotherapy resistance. Patients with colorectal cancer infrequently exhibit IFN and MHC signaling gene mutations and are generally resistant to immunotherapy. In exploring the integrity of IFN and MHC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c527f51c71638632136f527b19b4f7
https://doi.org/10.1158/2159-8290.cd-20-1571
https://doi.org/10.1158/2159-8290.cd-20-1571
Publikováno v:
Plant and Soil. 462:257-271
Plant-soil feedbacks may determine the long-term success of introduced species. Here we examined plant-soil feedbacks of a globally invasive shrub, Cytisus scoparius (hereafter Cytisus), which associates with multiple guilds of microbial mutualists a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a8d865858ac573693e79e5f785a4e09
https://doi.org/10.1007/s11104-020-04804-w
https://doi.org/10.1007/s11104-020-04804-w
Autor:
Linda Vatan, Peter Sajjakulnukit, Weiping Zou, Anna Pawłowska, Karen McLean, Marcin Cieslik, Shasha Li, Arkadiusz Czerwonka, Costas A. Lyssiotis, Yingjie Bian, Witold Zgodziński, Grzegorz Wallner, Shuang Wei, Houjun Xia, Jiali Yu, Sara Grove, Arul M. Chinnaiyan, Iwona Wertel, Joel Crespo, Ilona Kryczek, Wojciech Szeliga, Peng Liao, Zeribe C. Nwosu, Li Zhang, Karolina Okła, Daniel M. Kremer, J. Rebecca Liu, Jing Li, Wei Li
Publikováno v:
Nature. 585:277-282
Abnormal epigenetic patterns correlate with effector T cell malfunction in tumours1-4, but the cause of this link is unknown. Here we show that tumour cells disrupt methionine metabolism in CD8+ T cells, thereby lowering intracellular levels of methi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::586219f4f5d0387b32c97bc125dcf216
https://doi.org/10.1038/s41586-020-2682-1
https://doi.org/10.1038/s41586-020-2682-1