Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Sara Goldstein"'
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 40 (2021)
There is a considerable need for methods that allow quantitative determination in vitro and in vivo of transient oxidative species such as peroxynitrite (ONOOH/ONOO−) and superoxide (HO2•/O2•−). Cyclic hydroxylamines, which upon oxidation yie
Externí odkaz:
https://doaj.org/article/5b54eaf15cc14fd3baf2310c3c4213b6
Autor:
Yorihiro Nishimura, Noel P McLaughlin, Jieyan Pan, Sara Goldstein, Susan Hafenstein, Hiroyuki Shimizu, Jeffrey D Winkler, Jeffrey M Bergelson
Publikováno v:
PLoS Pathogens, Vol 11, Iss 10, p e1005184 (2015)
NF449, a sulfated compound derived from the antiparasitic drug suramin, was previously reported to inhibit infection by enterovirus A71 (EV-A71). In the current work, we found that NF449 inhibits virus attachment to target cells, and specifically blo
Externí odkaz:
https://doaj.org/article/3297c7bc6d0a44e89e49960f6999e85e
Publikováno v:
PLoS Genetics, Vol 6, Iss 9, p e1001095 (2010)
Repetitive sequences in eukaryotic genomes induce chromatin-mediated gene-silencing of juxtaposed genes. Many components that promote or antagonize silencing have been identified, but how heterochromatin causes variegated and heritable changes in gen
Externí odkaz:
https://doaj.org/article/adc2d8a869a94588a2d3807a6d5392cf
Autor:
Georg Bauer, Gabor Speier, Gabor Merenyi, Jozsef Kaizer, Sara Goldstein, Bernard T. Golding, Georg Gescheidt, Lidia Gebicka, Jerzy L. Gebicki, Chryssostomos Chatgilialoglu, Peter Wardman
Publikováno v:
CHIMIA, Vol 62, Iss 9 (2008)
Biologically relevant small radicals are at the focus of the working group 4 (WG4) of the COST Action CM0603 (Free Radicals in Chemical Biology, CHEMBIORADICAL). This article surveys the areas of research being undertaken by the partners in WG4. The
Externí odkaz:
https://doaj.org/article/4eb94a6a84654c8e90cb1d9059f29a83
Publikováno v:
Antioxidants, Vol 11, Iss 40, p 40 (2022)
Antioxidants
Antioxidants; Volume 11; Issue 1; Pages: 40
Antioxidants
Antioxidants; Volume 11; Issue 1; Pages: 40
There is a considerable need for methods that allow quantitative determination in vitro and in vivo of transient oxidative species such as peroxynitrite (ONOOH/ONOO−) and superoxide (HO2•/O2•−). Cyclic hydroxylamines, which upon oxidation yie
Autor:
Sara Goldstein, Amram Samuni
Publikováno v:
Free Radical Biology and Medicine. 160:837-844
In vivo, nitroxide antioxidants distribute within minutes throughout all tissues, but are reduced to their respective hydroxylamines due to the cellular reducing environment, which apparently limits their application. To distinguish their antioxidati
Publikováno v:
Free radical biologymedicine. 177
Asthma is characterized by airway inflammation, hyper-responsiveness, symptoms of dyspnea, wheezing and coughing. In most patients, asthma is well controlled using inhaled corticosteroids and bronchodilators. A minority of patients with asthma develo
Publikováno v:
Free radical biologymedicine. 171
Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with a poor prognosis and limited treatment options. Oxidative and nitrosative stress is implicated as one of the main pathogenic pathways in IPF. The rationale for the use of a
Publikováno v:
Journal of Coordination Chemistry. 71:1728-1737
Oxidation of hydroxamic acids (HXs) generates HNO, and it is not clear whether it is formed also in the presence of metal ions. The kinetics of the oxidation of HXs, such as acetohydroxamic acid, suberohydroxamic acid, and suberoylanilide hydroxamic
Publikováno v:
The Journal of Physical Chemistry A. 122:3747-3753
Hydroxamic acids (RC(O)NHOH) form a class of compounds that display interesting chemical and biological properties The chemistry of RC(O)NHOH) is associated with one- and two-electron oxidations forming the respective nitroxide radical (RC(O)NHO•)