Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sara Ghassemifar"'
Autor:
Christina Wong, Sara Ghassemifar, Daryl C. Drummond, Maja Razlog, Stephanie Grabow, Alexander Koshkaryev, Andrew J. Sawyer, James Suchy, Jennifer Richards, Eric M. Tam
Publikováno v:
Cancer Research. 79:2491-2491
Early attempts at using TNF superfamily members for anticancer therapies, TNF and FAS, led to serious systemic toxicities. However, the discovery of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) introduced an agonist capable of kill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2b19641ec0503d80783d6a36a522831
https://doi.org/10.1158/1538-7445.am2019-2491
https://doi.org/10.1158/1538-7445.am2019-2491
Autor:
Eric M. Tam, Sara Ghassemifar, Lia Luus, Yasmin Hashambhoy-Ramsay, Andrew J. Sawyer, Haluk Yuzugullu, Daryl C. Drummond, Birgit Schoeberl, Tim Maiwald, Peter K. Sorger, Maja Razlog, Hannah Hudson, Tamara Utermark, Violette Paragas, C. Patrick Reynolds, Diane Chai
Publikováno v:
Cancer Research. 79:700-700
In colorectal cancer (CRC), RAS mutated cancers comprise 30-50%, for which there are limited treatment options. Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) has been found to selectively induce cell death in 50% of the CRC ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5575ea81de2d1baf293555a92c3249a2
https://doi.org/10.1158/1538-7445.am2019-700
https://doi.org/10.1158/1538-7445.am2019-700
Autor:
Guan Wang, Reem Malek, Christopher M. Fulkerson, Sara Ghassemifar, Susan M. Mendrysa, Paul W. Snyder
Publikováno v:
Birth Defects Research Part A: Clinical and Molecular Teratology. 94:729-737
BACKGROUND Ly-1 antibody reactive clone (LYAR) is a nucleolar zinc finger protein that has been implicated in cell growth, self-renewal of embryonic stem cells, and medulloblastoma. To test whether LYAR is critical for cell growth and development, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6701a513d3f839fec6593ad353e361a4
https://doi.org/10.1002/bdra.23048
https://doi.org/10.1002/bdra.23048
Autor:
Cormac Cosgrove, James F. Sampson, Eric M. Tam, Alexander Koshkaryev, Andreas Raue, Galina Craig, Daryl C. Drummond, Sara Ghassemifar, Sara Movassaghian
Publikováno v:
Cancer Research. 78:2716-2716
Members of the tumor necrosis factor (TNF) superfamily of costimulatory receptors have emerged as promising targets for modulation of tumor infiltrating lymphocytes. Among these, 4-1BB (CD137) has a prominent role in promoting survival and expansion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8c858d94dde4b6c30845c5899e966a0
https://doi.org/10.1158/1538-7445.am2018-2716
https://doi.org/10.1158/1538-7445.am2018-2716
Autor:
Bambang Adiwijaya, Walid S. Kamoun, Lecia V. Sequist, M. Higgins, Peter A. Kaufman, Sara Ghassemifar, Sergio Santillana, Johannes Ettl, J. Marc Pipas, Joyce F. Liu
Publikováno v:
Journal of Clinical Oncology. 36:2524-2524
2524Background: Seribantumab (MM-121) is an anti-ErbB3 human monoclonal antibody being tested as an anti-cancer therapy for patients with high expression of heregulin mRNA in NSCLC (SHERLOC study, ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73b1c547650479caed3118569acf21af
https://doi.org/10.1200/jco.2018.36.15_suppl.2524
https://doi.org/10.1200/jco.2018.36.15_suppl.2524
Autor:
Neeraj Kohli, Dake Tamara, Haluk Yuzugullu, Violette Paragas, Lihui Xu, Greg Finn, Yasmin Hashambhoy-Ramsay, Maja Razlog, Birgit Schoeberl, Charlotte Mcdonagh, Melissa Geddie, Sara Ghassemifar, Marco Muda
Publikováno v:
Cancer Research. 77:22-22
Aberrant signaling of the FGFR pathway has long been known to promote tumorigenesis and angiogenesis across multiple cancer indications. However, the development of an effective and well-tolerated FGFR targeted inhibitor has been hindered by the need
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37975d8959833d5a7c00e934f77321c6
https://doi.org/10.1158/1538-7445.am2017-22
https://doi.org/10.1158/1538-7445.am2017-22
Autor:
Susan M. Mendrysa, Sara Ghassemifar
Publikováno v:
Neuroscience letters. 513(1)
A critical component of the cellular stress response, the p53 tumor suppressor protein must be functional for many cancer therapies to be effective. Adjuvant therapies that augment p53 function are predicted to sensitize tumor cells to cancer therapi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b70513e13d05a2838384e169e210440
https://pubmed.ncbi.nlm.nih.gov/22343310
https://pubmed.ncbi.nlm.nih.gov/22343310
The p53 tumor suppressor potently limits the growth of immature and mature neurons under conditions of cellular stress. Although loss of p53 function contributes to the pathogenesis of central nervous system (CNS) tumors, excessive p53 function is im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5febea11de379bd381bf517845615c2a
https://europepmc.org/articles/PMC3135640/
https://europepmc.org/articles/PMC3135640/
Autor:
Marie Kelly-Worden, Sara Ghassemifar
Publikováno v:
Advances in Planar Lipid Bilayers and Liposomes ISBN: 9780123743411
Artificial vesicles have been used for decades to examine reconstituted purified membrane proteins and reconstitution of pieces of cellular (mCs) or vesicular membranes (mVs). Reconstitution of vesicles into liposomes allows vesicular proteins to mai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a77145a22bf1de8c3fe267ebc5973025
https://doi.org/10.1016/s1554-4516(08)00207-x
https://doi.org/10.1016/s1554-4516(08)00207-x