Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sara Gabreilli"'
Autor:
Sarah Jane Halliday, Ken H. Young, Anthony J. Gill, Mark P. Hertzberg, Clare Gould, Gayathri Thillaiyampalam, William Stevenson, Simone Birch, Muhammed B. Sabdia, Xiaohong Tan, Zijun Y. Xu-Monette, Maher K. Gandhi, Lilia Merida de Long, Emad Uddin Abro, Annette Hernandez, Dipti Talaulikar, Sanjiv Jain, Robert Bird, Colm Keane, Joshua W.D. Tobin, Grace Gifford, Donna Cross, Soi Cheng Law, Sara Gabreilli
Publikováno v:
Blood advances. 4(7)
Blockade of the PD-1 axis has modest efficacy in diffuse large B-cell lymphoma (DLBCL), but data regarding LAG3 are sparse. The impact of LAG3 digital gene expression was tested in 309 patients with DLBCL treated with standard chemoimmunotherapy. Cel
Autor:
Annette Hernadez, Clare Gould, Joshua W.D. Tobin, Sara Gabreilli, Santiyagu M. Savarimuthu Francis, Simone Birch, Soi Cheng Law, William Stevenson, Anthony J. Gill, Mark P. Hertzberg, Robert Bird, Emad Uddin Abro, Sanjiv Jain, Colm Keane, Dipti Talaulikar, Sarah-Jane Halliday, Donna Cross, Maher K. Gandhi, Grace Gifford
Publikováno v:
Blood. 132:1576-1576
LAG3 is an immune checkpoint expressed on a variety of immune cells including a sub-population of 'exhausted' effector T cells and TREGs. Early-phase studies of anti-LAG3 mAb show promise in solid and haematological cancers. We have previously demons