Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sara G. Carlson"'
Publikováno v:
Journal of Biological Chemistry. 280:31156-31165
The endoplasmic reticulum is the site of synthesis and folding of secretory proteins and is sensitive to changes in the internal and external environment of the cell. Both physiological and pathological conditions may perturb the function of the endo
Publikováno v:
Trends in Cardiovascular Medicine. 11:131-138
The cell injury caused by oxidized lipoproteins was among the first findings that led to the theory that it is the oxidation of low-density lipoprotein (LDL), not just LDL concentration, that leads to arterial disease. Voluminous studies have now rev
Publikováno v:
Molecular and Cellular Biology. 13:4736-4744
gadd153 encodes a CCAAT/enhancer-binding protein (C/EBP)-related protein that lacks a functional DNA-binding domain. Since the gadd153 protein is capable of heterodimerizing with other C/EBPs, gadd153 may function as a negative regulator of these tra
Publikováno v:
Journal of Biological Chemistry. 267:20465-20470
gadd153 is a CCAAT/enhancer-binding protein (C/EBP)-related gene whose expression is induced in response to growth arrest and DNA damage. This investigation explored the possibility that Ca2+ might play a role in regulating expression of gadd 153. We
Publikováno v:
Molecular and Cellular Biology. 12:1528-1534
Prostaglandins (PG) of the A series are potent inhibitors of cell proliferation. Recently, it was shown that PGA2-induced growth arrest was associated with the increased synthesis of stress proteins encoded by the HSP70 gene family. In this study, we
Publikováno v:
Journal of cellular biochemistry. 102(3)
BAG-1 (Bcl-2 associated athanogene-1) is a multifunctional protein, linking cell proliferation, cell death, protein folding, and cell stress. In vivo, BAG-1 is expressed in growth plate and articular cartilage, and the expression of BAG-1 is decrease
Autor:
Eudora Eng, Terry D. Copeland, Sara G. Carlson, Eung-Gook Kim, Elizabeth J. Perlman, Barbara J. Ballermann
Publikováno v:
Journal of the American Society of Nephrology : JASN. 9(10)
The human gene set was originally identified as a component of the set-can fusion gene produced by a somatic translocation event in a case of acute undifferentiated leuke- mia. In the developing kidney, set was highly expressed in the zone of nephron
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 8(13)
We have explored the mechanisms involved in the induction of five stress-response genes (heme oxygenase [HO], c-fos, Egr-1, gadd153, and HSP70) in human diploid fibroblasts growth-arrested by treatment with the antiproliferative prostaglandin A2 (PGA
Publikováno v:
Brain research. Molecular brain research. 17(1-2)
Decreases in striatal dopamine receptors during aging are related to deficits in motor functions, and are highly correlated with the D2 receptor subtype. Some receptor loss is attributed to cell death, while the remainder is thought to be related to
Publikováno v:
Experimental cell research. 199(1)
Treatment of Hela cells with prostaglandin A 2 (PGA 2 ) resulted in a marked inhibition of cell proliferation which was associated with a significant induction of gadd153 mRNA, a member of a novel class of genes associated with g rowth a rrest and D