Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Sara Filippini"'
Autor:
Laura Morelli, Damiano Cancogni, Marta Tontini, Alberto Nilo, Sara Filippini, Paolo Costantino, Maria Rosaria Romano, Francesco Berti, Roberto Adamo, Luigi Lay
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 10, Iss 1, Pp 2367-2376 (2014)
A vaccine to prevent infections from the emerging Neisseria meningitidis X (MenX) is becoming an urgent issue. Recently MenX capsular polysaccharide (CPS) fragments conjugated to CRM197 as carrier protein have been confirmed at preclinical stage as p
Externí odkaz:
https://doaj.org/article/02b161b95d3743a199d770006c294956
Autor:
Guido Grandi, Immaculada Margarit, Emiliano Chiarot, Fabio Rigat, Karen S. Slobod, Frederick Wittke, Scott A. Halperin, Monica Fabbrini, Giovanna Tuscano, Elisabetta Frigimelica, Pietro Forte, Gilbert G.G. Donders, Sara Filippini, Roland Devlieger
Publikováno v:
The journal of infection
Objectives: The main aim of this exploratory study was to evaluate functional activity of antibodies elicited by a maternal Group B Streptococcus (GBS) investigational vaccine composed of capsular polysaccharides Ia, Ib, and III conjugated to genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b20a15bddb225d742b8c19892be2ef
https://doi.org/10.1016/j.jinf.2018.01.006
https://doi.org/10.1016/j.jinf.2018.01.006
Autor:
L. Arcidiacono, Derek T. O'Hagan, Simone Bufali, T. Uno, Fabio Rigat, Tom Y.-H. Wu, Sara Filippini, S. Vecchi
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 87:310-317
Next generation vaccine adjuvants include Toll like receptor agonists, which are mostly extracted from microorganisms, but synthetic small molecule TLR agonists have also been identified. However, their delivery systems have not been optimized for ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7219a2b8c1c4794922226bed84a32ff0
https://doi.org/10.1016/j.ejpb.2014.01.002
https://doi.org/10.1016/j.ejpb.2014.01.002
Autor:
Calman A. MacLennan, Daniela Proietti, Simona Rondini, Marta Tontini, Cristiana Balocchi, Andrew J. Pollard, Massimiliano Gavini, Gerd Pluschke, Francesco Berti, Emilia Cappelletti, Francesca Micoli, Sara Filippini, Erwin Swennen, Allan Saul, Maria Rosaria Romano, Gunnstein Norheim, Rino Rappuoli, Laura Santini, Roberto Adamo, Paolo Costantino
Publikováno v:
Proceedings of the National Academy of Sciences. 110:19077-19082
Neisseria meningitidis is a major cause of bacterial meningitis worldwide, especially in the African meningitis belt, and has a high associated mortality. The meningococcal serogroups A, W, and X have been responsible for epidemics and almost all cas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0a80b29bc0393bec12c3077d88fbd4
https://doi.org/10.1073/pnas.1314476110
https://doi.org/10.1073/pnas.1314476110
Autor:
Laura Polito, Paolo Costantino, Giulia Brogioni, Marta Tontini, Alberto Nilo, Qi Gao, Carole Harfouche, Francesco Berti, Maria Rosaria Romano, Luigi Lay, Sara Filippini, Roberto Adamo
Publikováno v:
ACS chemical biology 8 (2013): 2561–2567. doi:10.1021/cb400463u
info:cnr-pdr/source/autori:Gao Q.; Tontini M.; Brogioni G.; Nilo A.; Filippini S.; Harfouche C.; Polito L.; Romano M.R.; Costantino P.; Berti F.; Adamo R.; Lay L./titolo:Immunoactivity of protein conjugates of carba analogues from neisseria meningitidis a capsular polysaccharide/doi:10.1021%2Fcb400463u/rivista:ACS chemical biology/anno:2013/pagina_da:2561/pagina_a:2567/intervallo_pagine:2561–2567/volume:8
info:cnr-pdr/source/autori:Gao Q.; Tontini M.; Brogioni G.; Nilo A.; Filippini S.; Harfouche C.; Polito L.; Romano M.R.; Costantino P.; Berti F.; Adamo R.; Lay L./titolo:Immunoactivity of protein conjugates of carba analogues from neisseria meningitidis a capsular polysaccharide/doi:10.1021%2Fcb400463u/rivista:ACS chemical biology/anno:2013/pagina_da:2561/pagina_a:2567/intervallo_pagine:2561–2567/volume:8
Neisseria meningitidis type A (MenA) is a Gram-negative encapsulated bacterium that is a major cause of epidemic meningitis, especially in the sub-Saharan region of Africa. The development and manufacture of a liquid glycoconjugate vaccine against Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6731d62fa52987b575349bcf3dc918dc
https://doi.org/10.1021/cb400463u
https://doi.org/10.1021/cb400463u
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 44:1140-1142
Despite the lack of evidence in the literature, we report the case of a 25-year-old man involved in a road traffic accident, who had an inferior vena cava (IVC) injury and severe lung contusion with parenchymal bleeding requiring an extracorporeal me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67a98c0732f0bda8f23944598bfc009e
https://doi.org/10.1093/ejcts/ezt203
https://doi.org/10.1093/ejcts/ezt203
Autor:
Marta Tontini, Barbara Brogioni, Vittoria Pinto, Maria Rosaria Romano, Paolo Costantino, Roberto Adamo, Francesco Berti, Evita Balducci, Alberto Nilo, Elena Mori, Carole Harfouche, Simone Pecetta, Giulia Brogioni, Sara Filippini
Publikováno v:
Glycoconjugate journal. 31(9)
Multicomponent constructs, obtained by coupling different glycans to the carrier protein, have been proposed as a way to co-deliver multiple surface carbohydrates targeting different strains of one pathogen and reduce the number of biomolecules in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf13c3c53ba6fdb01cc5544f5e20f35
https://pubmed.ncbi.nlm.nih.gov/25256065
https://pubmed.ncbi.nlm.nih.gov/25256065
Autor:
Silvana Savino, David Goldblatt, Paolo Ruggiero, Laura Pancotto, Michèle A. Barocchi, Elena Mori, Bruno Galletti, Claudia Facciotti, Giuseppe Mancuso, Mitch Haston, Michele Pallaoro, Monica Moschioni, Rino Rappuoli, Claudia Gianfaldoni, Marzia Monica Giuliani, Salvatore Nocadello, Silvia Maccari, Mariagrazia Pizza, Elena Cartocci, Francesco Doro, Stefano Censini, Letizia Arcidiacono, Sara Filippini, Vega Masignani, Carole Harfouche
Publikováno v:
Infection and immunity. 80(1)
Streptococcus pneumoniae pilus 1 is present in 30 to 50% of invasive disease-causing strains and is composed of three subunits: the adhesin RrgA, the major backbone subunit RrgB, and the minor ancillary protein RrgC. RrgB exists in three distinct gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2bd11ca8b162a5135bb6e8d2fd2ab1
https://pubmed.ncbi.nlm.nih.gov/22083702
https://pubmed.ncbi.nlm.nih.gov/22083702
Autor:
Carole Harfouche, Vega Masignani, Paolo Ruggiero, Gabriella De Angelis, Esmeralda Bizzarri, Francesco Doro, Giuseppe Mancuso, Monica Moschioni, Michèle A. Barocchi, Elena Mori, Sara Filippini
Publikováno v:
Vaccine. 30(7)
RrgB321, a fusion protein of the three Streptococcus pneumoniae pilus-1 backbone RrgB variants, is protective in vivo against pilus islet 1 (PI-1) positive pneumococci. In addition, antibodies to RrgB321 mediate a complement-dependent opsonophagocyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0f10fabf0564923600b5422a19b99a
https://pubmed.ncbi.nlm.nih.gov/22210141
https://pubmed.ncbi.nlm.nih.gov/22210141
Autor:
Sara Filippini, Marco Agrifoglio, Francesco Alamanni, Elisa Merati, Alessandro Parolari, Gianfranco Lauri, Stefano Salis, Giulio Pompilio
Publikováno v:
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 39(5)
Objective: We aimed to identify independent risk factors predisposing toward postoperative surgical or percutaneous pericardial drainage following cardiac surgery, and to assess late survival. Methods: A retrospective review of preoperative, intra-op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf8835b7a5ee98d661cbf650877d375
https://pubmed.ncbi.nlm.nih.gov/21295488
https://pubmed.ncbi.nlm.nih.gov/21295488