Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sara Faouzi"'
Autor:
Xinpu Tang, Yi Pu, Haoning Peng, Kaixiu Li, Sara Faouzi, Tianjian Lu, Dan Pu, Michael Cerezo, Jianguo Xu, Lu Li, Caroline Robert, Shensi Shen
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1157-1168 (2023)
As a central node of protein synthesis, the cap-binding complex, eukaryotic translation initiation factor 4 F (eIF4F), is involved in cell homeostasis, development and tumorigenesis. A large body of literature exists on the regulation and function of
Externí odkaz:
https://doaj.org/article/2ce22105fa7342faa45c4c03c11f181c
Autor:
Shensi Shen, Sara Faouzi, Amandine Bastide, Sylvain Martineau, Hélène Malka-Mahieu, Yu Fu, Xiaoxiao Sun, Christine Mateus, Emilie Routier, Severine Roy, Laurent Desaubry, Fabrice André, Alexander Eggermont, Alexandre David, Jean-Yves Scoazec, Stéphan Vagner, Caroline Robert
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Melanoma persister cells are tolerant to anti-BRAF and anti-MEK inhibition and can trigger cancer relapse. Here the authors show that a subset of N6-methyladenosine modified mRNAs is translationally activated in persister cells. This preferential tra
Externí odkaz:
https://doaj.org/article/e47491eb7c3744b2a9a1e54104826b8f
Autor:
Giuseppina Claps, Sara Faouzi, Virginie Quidville, Feras Chehade, Shensi Shen, Stéphan Vagner, Caroline Robert
Publikováno v:
Nature Reviews Clinical Oncology. 19:749-762
High serum lactate dehydrogenase (LDH) levels are typically associated with a poor prognosis in many cancer types. Even the most effective drugs, which have radically improved outcomes in patients with melanoma over the past decade, provide only marg
Autor:
Caroline Robert, Stéphan Vagner, Jean-Yves Scoazec, Pascale Morel, SuFey Ong, Kristina Sorg, Sarah Warren, Jéremy Lupu, Emilie Routier, Sara Faouzi, Caroline Brard, Séverine Roy, Shensi Shen, Julien Adam, Isabelle Girault
Results of PLA, CD8 and PDL1 (MELscore) in all the samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa5d3e7b4d771f42fe8667c88c0ea8d
https://doi.org/10.1158/1078-0432.22482161.v1
https://doi.org/10.1158/1078-0432.22482161.v1
Autor:
Caroline Robert, Stéphan Vagner, Jean-Yves Scoazec, Pascale Morel, SuFey Ong, Kristina Sorg, Sarah Warren, Jéremy Lupu, Emilie Routier, Sara Faouzi, Caroline Brard, Séverine Roy, Shensi Shen, Julien Adam, Isabelle Girault
Purpose:Less than 50% of patients with melanoma respond to anti–programmed cell death protein 1 (anti–PD-1), and this treatment can induce severe toxicity. Predictive markers are thus needed to improve the benefit/risk ratio of immune checkpoint
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::130342ef5b960dbb0ebd0956b86de8bf
https://doi.org/10.1158/1078-0432.c.6530840
https://doi.org/10.1158/1078-0432.c.6530840
Autor:
Caroline Robert, Stéphan Vagner, Jean-Yves Scoazec, Pascale Morel, SuFey Ong, Kristina Sorg, Sarah Warren, Jéremy Lupu, Emilie Routier, Sara Faouzi, Caroline Brard, Séverine Roy, Shensi Shen, Julien Adam, Isabelle Girault
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d847eb45cb025e855425a9ce83ec5e1d
https://doi.org/10.1158/1078-0432.22482167
https://doi.org/10.1158/1078-0432.22482167
Autor:
Caroline Robert, Stéphan Vagner, Jean-Yves Scoazec, Pascale Morel, SuFey Ong, Kristina Sorg, Sarah Warren, Jéremy Lupu, Emilie Routier, Sara Faouzi, Caroline Brard, Séverine Roy, Shensi Shen, Julien Adam, Isabelle Girault
Kaplan Meier representation of the progression-free survival (PFS) and overall survival (OS) for PDL1, CD8, TIS and Melscore variables in all samples (exploratory and validation cohorts) with a recapitulive table of survival medians (NA : Not Availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eccd81f44e2537fc5aa6d59e7ceb6dd
https://doi.org/10.1158/1078-0432.22482170.v1
https://doi.org/10.1158/1078-0432.22482170.v1
Autor:
Jean-Yves Scoazec, Sara Faouzi, Amandine Bastide, Fabrice Andre, Shensi Shen, Séverine Roy, Emilie Routier, Hélène Malka-Mahieu, Caroline Robert, Yu Fu, Laurent Désaubry, Alexandre David, Alexander M.M. Eggermont, Stéphan Vagner, Xiaoxiao Sun, Christine Mateus, Sylvain Martineau
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-13360-6⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-13360-6⟩
Cancer persister cells tolerate anticancer drugs and serve as the founders of acquired resistance and cancer relapse. Here we show that a subpopulation of BRAFV600 mutant melanoma cells that tolerates exposure to BRAF and MEK inhibitors undergoes a r
Publikováno v:
Bulletin du Cancer. 106:887-895
Stage I germ-cell tumors are rare and highly curable diseases. As such, management of these tumours should carefully follow guidelines. Initial management is based on orchiectomy and several options as adjuvant therapy. Pro's and con's should be disc
Autor:
Jean-Yves Blay, Philippe Terrier, Sara Faouzi, Florence Duffaud, Olivier Mir, François Bertucci, Olivier Collard, Axel Le Cesne, Olivier Bouché, Nicolas Penel, Nicolas Isambert, Almudena Callejo, Thomas Chevalier
Publikováno v:
Targeted Oncology
Targeted Oncology, 2021, 16 (4), pp.485-492. ⟨10.1007/s11523-021-00820-7⟩
Targeted Oncology, 2021, 16 (4), pp.485-492. ⟨10.1007/s11523-021-00820-7⟩
Retrospective analyses suggest that patients with advanced KIT exon 9-mutated gastrointestinal stromal tumors (GISTs) receiving imatinib 800 mg (rather than 400 mg) daily have better outcomes. In the adjuvant setting, the question of the optimal dose