Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Sara Falvo"'
Autor:
Sara Falvo, Giulia Grillo, Debora Latino, Gabriella Chieffi Baccari, Maria Maddalena Di Fiore, Massimo Venditti, Giuseppe Petito, Alessandra Santillo
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
D-Aspartic Acid (D-Asp) affects spermatogenesis by enhancing the biosynthesis of the sex steroid hormones acting either through the hypothalamus-pituitary–testis axis or directly on Leydig cells. Recently, in vitro studies have also demonstrated th
Externí odkaz:
https://doaj.org/article/7967f70b97f046e1801384d3512f7c63
Autor:
Sara Falvo, Alessandra Santillo, Maria Maddalena Di Fiore, Massimo Venditti, Giulia Grillo, Debora Latino, Isabella Baccari, Giuseppe Petito, Gabriella Chieffi Baccari
Publikováno v:
Cells, Vol 13, Iss 16, p 1400 (2024)
D-aspartate (D-Asp) is an amino acid found in high concentrations in the testis and pituitary gland. Increasing evidence suggests that D-Asp promotes spermatogenesis by activating testosterone production in the Leydig cells via LH release from the pi
Externí odkaz:
https://doaj.org/article/c8078cdc5cfb4a18aa622d29893bb5dd
Autor:
Giulia Grillo, Sara Falvo, Debora Latino, Gabriella Chieffi Baccari, Massimo Venditti, Maria Maddalena Di Fiore, Sergio Minucci, Alessandra Santillo
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 274, Iss , Pp 116202- (2024)
Many laboratory studies demonstrated that the exposure to microplastics causes testosterone deficiency and spermatogenic impairment in mammals; however, the mechanism underlying this process remains still unclear. In this study, we investigated the e
Externí odkaz:
https://doaj.org/article/348e8414d3844172b0c68a6873ac6bda
Autor:
Debora Latino, Massimo Venditti, Sara Falvo, Giulia Grillo, Alessandra Santillo, Imed Messaoudi, Mariem Ben Rhouma, Sergio Minucci, Gabriella Chieffi Baccari, Maria Maddalena Di Fiore
Publikováno v:
Cells, Vol 13, Iss 6, p 523 (2024)
Mitochondria-Associated Endoplasmic Reticulum Membranes (MAMs) mediate the communication between the Endoplasmic Reticulum (ER) and the mitochondria, playing a fundamental role in steroidogenesis. This study aimed to understand how D-aspartate (D-Asp
Externí odkaz:
https://doaj.org/article/25f933911afa467a865f48f110d78ab8
Autor:
Sara Falvo, Sergio Minucci, Alessandra Santillo, Rosalba Senese, Gabriella Chieffi Baccari, Massimo Venditti
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundOverweight/obesity are metabolic disorder resulting from behavioral, environmental, and heritable causes. WHO estimates that 50% of adults and 30% of children and adolescents are overweight or obese, and, in parallel, an ongoing decline in
Externí odkaz:
https://doaj.org/article/ae4a9d31527a4c7692306c38160b1f42
Autor:
Alessandra Santillo, Sara Falvo, Massimo Venditti, Anna Di Maio, Gabriella Chieffi Baccari, Francesco Errico, Alessandro Usiello, Sergio Minucci, Maria Maddalena Di Fiore
Publikováno v:
Biomolecules, Vol 13, Iss 4, p 621 (2023)
High levels of free D-aspartate (D-Asp) are present in vertebrate testis during post-natal development, coinciding with the onset of testosterone production, which suggests that this atypical amino acid might participate in the regulation of hormone
Externí odkaz:
https://doaj.org/article/87889bd89c4f4d259ca20d2459e33c49
Autor:
Gabriella Chieffi Baccari, Sara Falvo, Antonia Lanni, Maria Maddalena Di Fiore, Federica Cioffi, Alessandra Santillo
Publikováno v:
Animals, Vol 12, Iss 14, p 1840 (2022)
The morphological features and relative number of mast cells (MCs) were studied in the skin and exorbital lacrimal glands of hypothyroid Wistar rats, Rattus norvegicus. Hypothyroidism significantly increased the number of MCs (up to 4.5-fold) and his
Externí odkaz:
https://doaj.org/article/3bddb857141946358f11cb1329a0bf96
Autor:
Alessandra Santillo, Antonia Giacco, Sara Falvo, Federica Di Giacomo Russo, Rosalba Senese, Maria Maddalena Di Fiore, Gabriella Chieffi Baccari, Antonia Lanni, Pieter de Lange
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
The present investigation was undertaken to increase our insight into the molecular basis of the physiological changes in rat testis induced by food withdrawal, and to clarify whether reduced testicular function can be ameliorated by mild exercise. M
Externí odkaz:
https://doaj.org/article/2bed7170b14d4396961ea3a4ce769a67
Autor:
Sara Falvo, Luigi Rosati, Maria Maddalena Di Fiore, Federica Di Giacomo Russo, Gabriella Chieffi Baccari, Alessandra Santillo
Publikováno v:
Animals, Vol 11, Iss 6, p 1729 (2021)
The quail Coturnix coturnix is a seasonal breeding species, with the annual reproductive cycle of its testes comprising an activation phase and a regression phase. Our previous results have proven that the testicular levels of both 17β-estradiol (E2
Externí odkaz:
https://doaj.org/article/b664afadad9c4fea87bdfb868b4004d3
Autor:
Luigi Rosati, Sara Falvo, Gabriella Chieffi Baccari, Alessandra Santillo, Maria Maddalena Di Fiore
Publikováno v:
Animals, Vol 11, Iss 6, p 1763 (2021)
Estrogens are important physiological regulators of testicular activity in vertebrates. Estrogen levels depend on the activity of P450 aromatase, the enzyme responsible for the irreversible conversion of testosterone into 17β-estradiol. Therefore, P
Externí odkaz:
https://doaj.org/article/4224690bc1b9456b8354ab388bc590e0