Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Sara F. Tufa"'
Autor:
Bon-hyeock Koo, Yeon-Ju Lee, Na Rae Park, Su Chin Heo, David M. Hudson, Aysel A. Fernandes, Chet S. Friday, Michael W. Hast, David T. Corr, Douglas R. Keene, Sara F. Tufa, Nathaniel A. Dyment, Kyu Sang Joeng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The biological mechanisms regulating tenocyte differentiation and morphological maturation have not been well-established, partly due to the lack of reliable in vitro systems that produce highly aligned collagenous tissues. In this study, we
Externí odkaz:
https://doaj.org/article/cce7e84906324ac18d089ea546ee2e81
Autor:
William Stone, Chloe Strege, William Miller, Aron M. Geurts, Michael Grzybowski, Megan Riddle, Christopher Lees, Cindy Eide, Douglas R. Keene, Sara F. Tufa, Davis Seelig, John McGrath, Jakub Tolar
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/cf2016776dcd4fedae698106db769d20
Autor:
Matthew William Grol, Nele A Haelterman, Joohyun Lim, Elda M Munivez, Marilyn Archer, David M Hudson, Sara F Tufa, Douglas R Keene, Kevin Lei, Dongsu Park, Cole D Kuzawa, Catherine G Ambrose, David R Eyre, Brendan H Lee
Publikováno v:
eLife, Vol 10 (2021)
Osteogenesis imperfecta (OI) is characterized by short stature, skeletal deformities, low bone mass, and motor deficits. A subset of OI patients also present with joint hypermobility; however, the role of tendon dysfunction in OI pathogenesis is larg
Externí odkaz:
https://doaj.org/article/261397809146433d8b407ede35b7702f
Autor:
Guak-Kim Tan, Brian A Pryce, Anna Stabio, John V Brigande, ChaoJie Wang, Zheng Xia, Sara F Tufa, Douglas R Keene, Ronen Schweitzer
Publikováno v:
eLife, Vol 9 (2020)
Studies of cell fate focus on specification, but little is known about maintenance of the differentiated state. In this study, we find that the mouse tendon cell fate requires continuous maintenance in vivo and identify an essential role for TGFβ si
Externí odkaz:
https://doaj.org/article/08b49814dff4413798a4ba6fddbb0ae8
Publikováno v:
Matrix Biology. 110:151-173
Ocular anterior segment dysgenesis (ASD) refers to a collection of developmental disorders affecting the anterior structures of the eye. Although a number of genes have been implicated in the etiology of ASD, the underlying pathogenetic mechanisms re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b3a68d7328902e0cc13bc5ddd9ae00
https://doi.org/10.1016/j.matbio.2022.05.001
https://doi.org/10.1016/j.matbio.2022.05.001
Autor:
Irina Gurevich, Pooja Agarwal, PeiPei Zhang, John A. Dolorito, Stacie Oliver, Henry Liu, Nicholas Reitze, Nikhil Sarma, Isin Sinem Bagci, Kunju Sridhar, Visesha Kakarla, Vamsi K. Yenamandra, Mark O’Malley, Marco Prisco, Sara F. Tufa, Douglas R. Keene, Andrew P. South, Suma M. Krishnan, M. Peter Marinkovich
Publikováno v:
Nature Medicine. 28:780-788
Recessive dystrophic epidermolysis bullosa (RDEB) is a lifelong genodermatosis associated with blistering, wounding, and scarring caused by mutations in COL7A1, the gene encoding the anchoring fibril component, collagen VII (C7). Here, we evaluated b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce9c26f71edbe1ea4feaf5906f51c6c4
https://doi.org/10.1038/s41591-022-01737-y
https://doi.org/10.1038/s41591-022-01737-y
Autor:
Yoshihiro Ishikawa, Yuki Taga, Thibault Coste, Sara F. Tufa, Douglas R. Keene, Kazunori Mizuno, Elisabeth Tournier-Lasserve, Douglas B. Gould
Publikováno v:
The Journal of biological chemistry, vol 298, iss 12
Collagens are the most abundant proteins in the body and among the most biosynthetically complex. A molecular ensemble of over 20 endoplasmic reticulum resident proteins participates in collagen biosynthesis and contributes to heterogeneous post-tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dbeff3dfb1980b0d8730a3cad73f362
https://escholarship.org/uc/item/0gs5w663
https://escholarship.org/uc/item/0gs5w663
Publikováno v:
Stem Cell Reports
Summary Understanding cell recruitment in damaged tendons is critical for improvements in regenerative therapy. We recently reported that targeted disruption of transforming growth factor beta (TGFβ) type II receptor in the tendon cell lineage (Tgfb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f453f6bdeeab848ab04187133375f29c
http://europepmc.org/articles/PMC8693658
http://europepmc.org/articles/PMC8693658
Autor:
Douglas R. Keene, Amel Dudakovic, Bashar Hasan, Scott M. Riester, Andre J. van Wijnen, Deepanwita Pal, Ronen Schweitzer, Sara F. Tufa
Publikováno v:
Stem Cells Dev
An efficient musculoskeletal system depends on the precise assembly and coordinated growth and function of muscles, skeleton, and tendons. However, the mechanisms that drive integrated musculoskeletal development and coordinated growth and differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b36f4e39eed7bd8de9429febc87d1c91
https://doi.org/10.1089/scd.2020.0209
https://doi.org/10.1089/scd.2020.0209
Autor:
Jihee Sohn, Jelena Milosevic, Thomas Brouse, Najihah Aziz, Jenna Elkhoury, Suya Wang, Alexander Hauschild, Nick van Gastel, Murat Cetinbas, Sara F. Tufa, Douglas R. Keene, Ruslan I. Sadreyev, William T. Pu, David B. Sykes
Publikováno v:
Blood advances, (2022)
Barth syndrome is an inherited X-linked disorder that leads to cardiomyopathy, skeletal myopathy, and neutropenia. These symptoms result from the loss of function of the enzyme TAFAZZIN, a transacylase located in the inner mitochondrial membrane that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49de05b647a9f645324a100d38d6ae3
https://hdl.handle.net/2078.1/259156
https://hdl.handle.net/2078.1/259156