Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sara Esteban-García"'
Autor:
Mercedes M. Pérez-Jiménez, José M. Monje-Moreno, Ana María Brokate-Llanos, Mónica Venegas-Calerón, Alicia Sánchez-García, Paula Sansigre, Amador Valladares, Sara Esteban-García, Irene Suárez-Pereira, Javier Vitorica, José Julián Ríos, Marta Artal-Sanz, Ángel M. Carrión, Manuel J. Muñoz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Sul-2 is a steroid sulfatase in c.elegans. Here the authors show that, in the absence of sul-2 enzymatic activity, worm lifespan is increased, and that chemical inhibition ameliorates symptoms of neurodegenerative disorders in worms and mice.
Externí odkaz:
https://doaj.org/article/873769f1ad43491084d967f67bef724d
Autor:
José Ríos, Amador Valladares, Irene Suárez-Pereira, Mónica Venegas-Calerón, José M. Monje-Moreno, Paula Sansigre, Sara Esteban-García, Marta Artal-Sanz, Manuel Muñoz, Javier Vitorica, Angel M. Carrión, Alicia Sánchez-García, Ana María Brokate-Llanos, Mercedes M. Pérez-Jiménez
Publikováno v:
idUS: Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla
Universidad de Sevilla (US)
Nature Communications
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
idUS. Depósito de Investigación de la Universidad de Sevilla
12 Páginas.-- 5 Figuras
Aging and fertility are two interconnected processes. From invertebrates to mammals, absence of the germline increases longevity. Here we show that loss of function of sul-2, the Caenorhabditis elegans steroid sulfatase
Aging and fertility are two interconnected processes. From invertebrates to mammals, absence of the germline increases longevity. Here we show that loss of function of sul-2, the Caenorhabditis elegans steroid sulfatase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128e349166f272ab02aca1badb82eb4c
Autor:
Irene Suárez-Pereira, Sara Esteban-García, Alicia Sánchez-García, Javier Vitorica, Amador Valladares, Angel M. Carrión, Mercedes M. Pérez-Jiménez, José Ríos, José Manuel Monje, Manuel Muñoz, Mónica Venegas-Calerón, Paula Sansigre, Marta Artal-Sanz
Aging and fertility are two interconnected processes. From invertebrates to mammals, absence of the germline increases longevity by a still not fully understood mechanism. We find that loss of function of sul-2, the Caenorhabditis elegans steroid sul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21a92a8930b3582f601602bb81cc4eb9
https://doi.org/10.1101/541730
https://doi.org/10.1101/541730