Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sara El-Sahli"'
Autor:
Karan Mediratta, Sara El-Sahli, Marie Marotel, Muhammad Z. Awan, Melanie Kirkby, Ammar Salkini, Reem Kurdieh, Salman Abdisalam, Amit Shrestha, Chiara Di Censo, Andrew Sulaiman, Sarah McGarry, Jessie R. Lavoie, Zhen Liu, Seung-Hwan Lee, Xuguang Li, Giuseppe Sciumè, Vanessa M. D’Costa, Michele Ardolino, Lisheng Wang
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionChemotherapy remains the mainstay treatment for triple-negative breast cancer (TNBC) due to the lack of specific targets. Given a modest response of immune checkpoint inhibitors in TNBC patients, improving immunotherapy is an urgent and c
Externí odkaz:
https://doaj.org/article/10213cd0c20d41adb4e2783bba54bf80
Autor:
Sara El-Sahli, Khang Hua, Andrew Sulaiman, Jason Chambers, Li Li, Eliya Farah, Sarah McGarry, Dan Liu, Peiyong Zheng, Seung-Hwan Lee, Jiefeng Cui, Marc Ekker, Marceline Côté, Tommy Alain, Xuguang Li, Vanessa M. D’Costa, Lisheng Wang, Suresh Gadde
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-10 (2021)
Abstract Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer, accounting for the majority of breast cancer-related death. Due to the lack of specific therapeutic targets, chemotherapeutic agents (e.g., paclitaxel) rem
Externí odkaz:
https://doaj.org/article/01bd15f375e049938f736c0619b78c47
Autor:
Sarah Jane Laframboise, Thomas Bailey, Anh-Thu Dang, Mercedes Rose, Zier Zhou, Matthew D. Berg, Stephen Holland, Sami Aftab Abdul, Kaela O'Connor, Sara El-Sahli, Dominique M. Boucher, Garrett Fairman, Jacky Deng, Katherine Shaw, Nathaniel Noblett, Alexa D’Addario, Madelaine Empey, Keaton Sinclair
Publikováno v:
Biochemistry and Cell Biology.
Graduate students are vital to the creation of research and innovation in Canada. The National Graduate Student Finance Survey was launched in 2021 by the Ottawa Science Policy Network to investigate the financial realities of Canadian graduate stude
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::407c7d6336af5aa906b21fd1ab765520
https://doi.org/10.1139/bcb-2023-0021
https://doi.org/10.1139/bcb-2023-0021
Autor:
Lisheng Wang, Suresh Gadde, Daniel Figeys, Sheng Liu, Seung-Hwan Lee, Yevgeniya Le, Tommy Alain, Greg O. Cron, Marceline Côté, Alexandra Phan, Jason Chambers, Li Li, Sara El-Sahli, Sarah McGarry, Andrew Sulaiman
Triple-negative breast cancer (TNBC) accounts disproportionally for the majority of breast cancer–related deaths throughout the world. This is largely attributed to lack of a specific therapy capable of targeting both bulk tumor mass and cancer ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2581a0012fe3e63926dede22901cc174
https://doi.org/10.1158/1535-7163.c.6539433.v1
https://doi.org/10.1158/1535-7163.c.6539433.v1
Autor:
Lisheng Wang, Suresh Gadde, Daniel Figeys, Sheng Liu, Seung-Hwan Lee, Yevgeniya Le, Tommy Alain, Greg O. Cron, Marceline Côté, Alexandra Phan, Jason Chambers, Li Li, Sara El-Sahli, Sarah McGarry, Andrew Sulaiman
Supplementary figures S1-S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576bb68b391b58cd1bb0c5ac7169daa8
https://doi.org/10.1158/1535-7163.22509894
https://doi.org/10.1158/1535-7163.22509894
Autor:
Frederic St-Denis-Bissonnette, Rachil Khoury, Karan Mediratta, Sara El-Sahli, Lisheng Wang, Jessie R. Lavoie
Publikováno v:
Cancers, Vol 14, Iss 451, p 451 (2022)
Cancers
Cancers
Simple Summary Triple-negative breast cancer (TNBC) is the deadliest subtype of breast cancer, with limited treatment options. This review summarizes the most recent applications of extracellular vesicles (EVs) in TNBC as diagnostic/prognostic biomar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290859e48cf2900a609db5869b099405
https://www.mdpi.com/2072-6694/14/2/451
https://www.mdpi.com/2072-6694/14/2/451
Publikováno v:
Current cancer drug targets. 22(5)
Abstract: Triple-negative breast cancer (TNBC) is a subtype of breast cancer that lacks receptors for targeted therapy. Consequently, chemotherapy is currently the mainstay of systemic treatment options. However, the enrichment of cancer stem cells (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e111dc4775d32c9186a5c8d072ee93
https://pubmed.ncbi.nlm.nih.gov/34970954
https://pubmed.ncbi.nlm.nih.gov/34970954
Publikováno v:
Cancers, Vol 12, Iss 3529, p 3529 (2020)
Cancers
Cancers
Simple Summary The breakthrough of immunotherapy in melanoma has generated a glimmer of hope for lethal triple negative breast cancer (TNBC). This review summarizes the recent advances, challenges and potential new approaches of immunotherapy in TNBC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3102927624f0b45a69e6873f3ef734f
https://www.mdpi.com/2072-6694/12/12/3529
https://www.mdpi.com/2072-6694/12/12/3529
Autor:
Lisheng Wang, Sara El-Sahli
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 9125, p 9125 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 9125, p 9125 (2020)
Metabolic reprogramming of cancer is now considered a hallmark of many malignant tumors, including breast cancer, which remains the most commonly diagnosed cancer in women all over the world. One of the main challenges for the effective treatment of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3c493baa7678b654690c2944065715
https://pubmed.ncbi.nlm.nih.gov/33266219
https://pubmed.ncbi.nlm.nih.gov/33266219
Publikováno v:
Cancers, Vol 11, Iss 7, p 904 (2019)
Cancers
Cancers
The Wingless (Wnt)/β-catenin pathway has long been associated with tumorigenesis, tumor plasticity, and tumor-initiating cells called cancer stem cells (CSCs). Wnt signaling has recently been implicated in the metabolic reprogramming of cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8c2817a68c3a26d275c53daa750ef3
https://www.mdpi.com/2072-6694/11/7/904
https://www.mdpi.com/2072-6694/11/7/904