Výsledky vyhledávání - "Sara E. Shepherd"

Effect of conjugation methodology, carrier protein, and adjuvants on the immune response to Staphylococcus aureus capsular polysaccharides

Autor: Yun Hee Cho, Abbas Hawwari, Sara E. Shepherd, Robert B. Naso, Amy Burns, Scott Winston, Richard T. Coughlin, Xiuru Li, Ali Ibrahim Fattom

Publikováno v: Vaccine. 13:1288-1293

Conjugate vaccines were prepared with S. aureus type 8 capsular polysaccharide (CP) using three carrier proteins: Pseudomonas aeruginosa exotoxin A (ETA), a non-toxic recombinant ETA (rEPA), and diphtheria toxoid (DTd). Adipic acid dihydrazide (ADH)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eedfe1528c9148649991edb20b65c93
https://doi.org/10.1016/0264-410x(95)00052-3

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Identification of an autologous insulin B chain peptide as a target antigen for H-2Kb-restricted cytotoxic T lymphocytes

Autor: Y Paterson, James M. Sheil, Sara E. Shepherd, G F Klimo

Publikováno v: The Journal of Experimental Medicine

We have examined the CD8+ peripheral T cell repertoire of C57BL/6 (H-2b) mice for cytotoxic T lymphocyte (CTL) reactivities to insulin, using in vitro immunization with a chymotryptic digest of reduced bovine insulin. The results presented in this st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efa4478259509473c39f2550ec29ddb
https://doi.org/10.1084/jem.175.2.545

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Presentation of a horse cytochrome c peptide by multiple H-2b class I major histocompatibility complex (MHC) molecules to C57BL/6- and bm1-derived cytotoxic T lymphocytes: presence of a single MHC anchor residue may confer efficient peptide-specific CTL recognition

Autor: Todd D. Schell, Yvonne Paterson, Sara E. Shepherd, James M. Sheil, John M. Kioschos, Gerald F. Klimo

Publikováno v: European journal of immunology. 24(9)

In this study the immunogenic tryptic fragment from a horse cytochrome c (cyt c) digest recognized by cytotoxic T lymphocytes (CTL), induced by in vitro peptide stimulation from C57BL/6 (B6) and mutant B6.C-H-2bm1 (bm1) mice is identified. An identic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c91a383a5e2e0ee96aa9a4e9e33e6668
https://pubmed.ncbi.nlm.nih.gov/7522163

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Selective reactivity of CD8-independent T lymphocytes to a cytotoxic T lymphocyte-selected H-2Kb mutant altered at position 222 in the alpha 3 domain

Autor: Stanley G. Nathenson, James M. Sheil, Sara E. Shepherd, Rui Sun

Publikováno v: European journal of immunology. 22(3)

To study the structural basis for specificity and affinity of cytotoxic T lymphocytes for major histocompatibility complex/peptide complexes, we have employed a cytotoxic T lymphocyte (CTL)-mediated immunoselection approach to obtain H-2Kb structural

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5edff919d72b1fd306c5f85f7620cdd
https://pubmed.ncbi.nlm.nih.gov/1547812

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Evidence that the antigen receptors of cytotoxic T lymphocytes interact with a common recognition pattern on the H-2Kb molecule

Autor: Cole T. Thomson, Sara E. Shepherd, Rui Sun, Stanley G. Nathanson, Steve S. Geier, James M. Sheil

Publikováno v: Immunity. (5):573-582

Recognition of class I MHC antigens involves interaction between TCRs of cytotoxic T lymphocytes (CTL) and the two a helices of MHC molecules. Using a combined panel of H-2K b mutants selected by either a CTL clone or MAbs, we have shown evidence tha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b3dc8b3134cc4922e31b0a597adf9b

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Protective efficacy of antibodies to the Staphylococcus aureus type 5 capsular polysaccharide in a modified model of endocarditis in rats

Autor: Vincent J. Carey, Jean C. Lee, Jin-Sir Park, Ali Ibrahim Fattom, Sara E. Shepherd

Publikováno v: Scopus-Elsevier

The protective efficacy of antibodies to the Staphylococcus aureus type 5 capsular polysaccharide (CP5) was examined in a modified model of catheter-induced endocarditis. Rats were catheterized by surgically passing a polyethylene catheter through th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7db2572112fa69d484e41e6895eb8d3
http://www.scopus.com/inward/record.url?eid=2-s2.0-0030863413&partnerID=MN8TOARS

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