Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sara E. Morin"'
Autor:
Janice M. Friis, Charlotte Wu, Sara E. Morin, Joaquim Trias, Bore Raju, Wade J. Adams, Ford Charles W, Ronda D. Schaadt, Stuart Lam, Joe Palandra, Dinesh V. Patel, Joseph Zhou, Maria Courtney, Mikhail F. Gordeev, Sara Lopez, Gary E. Zurenko, C J Hackbarth, Upinder Singh, Robert C. Gadwood, Zhengyu Yuan, Kathleen Mortell
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:4209-4212
Combinatorial libraries of N-acylated 5-(S)-aminomethyloxazolidinone derivatives of S-oxide and S,S-dioxide tetrahydro-4(2H)-thiopyranyl and thiomorpholine phenyloxazolidinone series have been synthesized on a solid phase and evaluated for antimicrob
Autor:
Gary W. Luehr, Jonathan M. Evans, Gage James R, Barbachyn Michael R, Joaquim Trias, Christian N. Parker, Lee S. Banitt, Gary E. Zurenko, Sara E. Morin, Dinesh V. Patel, Mikhail F. Gordeev, C. Hackbarth, Richard White, Marcela Gomez
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:4213-4216
Antimicrobial compounds incorporating oxazolidinone and quinolone pharmacophore substructures have been synthesized and evaluated. Representative analogues 2, 5, and 6 display an improved potency versus linezolid against gram-positive and fastidious