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of 3
pro vyhledávání: '"Sara E Pour"'
Autor:
Debashish Ray, Kaitlin U. Laverty, Arttu Jolma, Kate Nie, Reuben Samson, Sara E. Pour, Cyrus L. Tam, Niklas von Krosigk, Syed Nabeel-Shah, Mihai Albu, Hong Zheng, Gabrielle Perron, Hyunmin Lee, Hamed Najafabadi, Benjamin Blencowe, Jack Greenblatt, Quaid Morris, Timothy R. Hughes
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Thousands of RNA-binding proteins (RBPs) crosslink to cellular mRNA. Among these are numerous unconventional RBPs (ucRBPs)—proteins that associate with RNA but lack known RNA-binding domains (RBDs). The vast majority of ucRBPs have unchara
Externí odkaz:
https://doaj.org/article/1bc102f75ce84e278ddced7e0d6825bd
Autor:
Kaitlin U Laverty, Arttu Jolma, Sara E Pour, Hong Zheng, Debashish Ray, Quaid Morris, Timothy R Hughes
Publikováno v:
Nucleic acids research. 50(19)
Modelling both primary sequence and secondary structure preferences for RNA binding proteins (RBPs) remains an ongoing challenge. Current models use varied RNA structure representations and can be difficult to interpret and evaluate. To address these
Publikováno v:
NAR Genomics and Bioinformatics. 5
Cleavage and polyadenylation (CPA) sites define eukaryotic gene ends. CPA sites are associated with five key sequence recognition elements: the upstream UGUA, the polyadenylation signal (PAS), and U-rich sequences; the CA/UA dinucleotide where cleava