Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Sara E Hillman"'
Autor:
Janelle M Veazey, Timothy J Chapman, Timothy R Smyth, Sara E Hillman, Sophia I Eliseeva, Steve N Georas
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216056 (2019)
The airway epithelial barrier is critical for preventing pathogen invasion and translocation of inhaled particles into the lung. Epithelial cells also serve an important sentinel role after infection and release various pro-inflammatory mediators tha
Externí odkaz:
https://doaj.org/article/f45762c71b8447ed9d938c760a934fc3
Autor:
Janelle M. Veazey, Sophia I Eliseeva, Sara E. Hillman, Kristie Stiles, Timothy R. Smyth, Charlotte E. Morrissey, Erika J. Tillotson, Dave J. Topham, Timothy J. Chapman, Steve N. Georas
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
RationaleProtein kinase D (PKD) is a serine/threonine kinase family that is involved in a wide array of signaling pathways. Although PKD has been implicated in immune responses, relatively little is known about the function of PKD in the lung or duri
Autor:
B. Paige Lawrence, Christopher D. Kassotis, Susan C. Nagel, Timothy J. Chapman, Jacques Robert, Sara E. Hillman, Lisbeth A. Boule, Steve N. Georas, Colleen O’Dell
Publikováno v:
Toxicological Sciences. 163:639-654
Chemicals used in unconventional oil and gas (UOG) operations have the potential to cause adverse biological effects, but this has not been thoroughly evaluated. A notable knowledge gap is their impact on development and function of the immune system
Autor:
Steve N. Georas, Timothy J. Chapman, Sara A. Knowlden, Renukadevi Patil, Sara E. Hillman, Gabor Tigyi, Duane D. Miller
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 54:402-409
Lysophosphatidic acid (LPA) is a pleiotropic lipid signaling molecule associated with asthma pathobiology. LPA elicits its effects by binding to at least six known cell surface G protein-coupled receptors (LPA1-6) that are expressed in the lung in a
Autor:
Janelle Veazey, Timothy J Chapman, Timothy R Smyth, Sara E Hillman, Sophia I Eliseeva, Steve N Georas
Publikováno v:
The Journal of Immunology. 204:245.13-245.13
Summary Antivirals targeting host proteins may slow development of viral resistance and work against multiple viruses. The serine/threonine kinase protein kinase D (PKD) is one promising target as others have shown inhibiting PKD restricts rhinovirus
Autor:
Timothy Smyth, Nicole Ransom, Sophia Eliseeva, Janelle Veazey, Kim Le, Jon Meddings, Sara E. Hillman, Steve N. Georas
Publikováno v:
J Asthma
OBJECTIVE: Airway epithelial barrier dysfunction is emerging as an important feature of asthma pathogenesis, but this is difficult to measure in individual subjects. We aimed to develop a non-invasive way to measure airway permeability in asthma. MET
Autor:
Jesse D. Sengillo, Edward Zuniga, David H. Perlmutter, E. Dale Abel, Darryl C. De Vivo, John S. Sullivan, Herbert J. Meiselman, Rosalinda B. Wenby, Sanket V Rege, Yoichiro Nishida, Amy R. Nelson, Pan Kong, Robert D. Bell, Jacob Makshanoff, Abhay P. Sagare, Jamie Soto, Berislav V. Zlokovic, Ethan A. Winkler, Sara E. Hillman, Zhen Zhao
Publikováno v:
Nature Neuroscience. 18:521-530
The glucose transporter GLUT1 at the blood-brain barrier (BBB) mediates glucose transport into the brain. Alzheimer's disease is characterized by early reductions in glucose transport associated with diminished GLUT1 expression at the BBB. Whether GL
Autor:
Steve N. Georas, Janelle Veazey, Sophia Eliseeva, Timothy Smyth, Timothy J. Chapman, Sara E. Hillman
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 5, p e0216056 (2019)
PLoS ONE, Vol 14, Iss 5, p e0216056 (2019)
The airway epithelial barrier is critical for preventing pathogen invasion and translocation of inhaled particles into the lung. Epithelial cells also serve an important sentinel role after infection and release various pro-inflammatory mediators tha
Publikováno v:
Journal of Allergy and Clinical Immunology. 135:AB150