Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sara Deakin"'
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 6, Pp 1246-1253 (2008)
The subfraction distribution of HDL-associated peptides has implications for their functions and the impact of pathological modifications to lipoprotein metabolism on these functions. We have analyzed the subfraction distribution of paraoxonase-1 (PO
Externí odkaz:
https://doaj.org/article/ca8869d6810441c8814b1b1a9c8cf548
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 4, Pp 528-535 (2001)
There are considerable variations in serum concentrations of the high density lipoprotein (HDL)-associated enzyme, paraoxonase (PON), which is an important determinant of the antioxidant capacity of HDL. The present study examined the hypothesis that
Externí odkaz:
https://doaj.org/article/4cd8286d8cc8442aa4a98b21ddcd44b0
Autor:
Ursula Seidler, Marie-Claude Brulhart-Meynet, Anurag K. Singh, Theo J.C. Van Berkel, Richard W. James, Sara Deakin, Brigitte Riederer, Ruud Out
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology, Vol. 30, No 11 (2010) pp. 2121-2127
Objective— To examine the contribution of the scavenger receptor (SR) BI to the mechanism by which high-density lipoprotein (HDL) acquires paraoxonase-1 (PON1). Methods and Results— Serum PON1 activity contributes to the antioxidant capacity of H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c4485ddac67ac4787ac8db574b623f9
https://doi.org/10.1161/atvbaha.110.209122
https://doi.org/10.1161/atvbaha.110.209122
Publikováno v:
Pharmacogenetics and Genomics, Vol. 20, No 7 (2010) pp. 455-458
Statins act by reducing hepatic cholesterol synthesis, thus stimulating uptake of serum cholesterol. Statin therapy modulates a number of genes involved in hepatic cholesterol homeostasis. These have rarely been analyzed simultaneously in the same ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f9f174bfc7a9179b777146ce4b9723
https://doi.org/10.1097/fpc.0b013e32833a9328
https://doi.org/10.1097/fpc.0b013e32833a9328
Autor:
Sherri Bisset, Paul Aveyard, Sara Deakin, Wolfgang A. Markham, Christopher Bridle, Emma R Lancashire
Publikováno v:
Addiction. 103:155-161
AIM: To show that schools achieving higher examination pass and lower truancy rates than expected, given that their pupil populations (high value-added schools) are associated with a lower incidence of smoking among pupils (13-14 years). DESIGN: Valu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::585c23a3ecd55c8070ccc4a5af74a14d
https://doi.org/10.1111/j.1360-0443.2007.02020.x
https://doi.org/10.1111/j.1360-0443.2007.02020.x
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 27:1146-1152
Objective— The purpose of this study was to analyze the consequences of HDL oxidation for paraoxonase-1 metabolism and function. Methods and Results— HDL was oxidized with AAPH, copper ions, and hypochlorite. Secretion studies were performed usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b944cc9b5cea5a3399c8aa0a61e14de
https://doi.org/10.1161/atvbaha.107.141747
https://doi.org/10.1161/atvbaha.107.141747
Publikováno v:
Atherosclerosis. 179:17-25
Paraoxonase-1 (PON1) requires a suitable acceptor complex for its secretion from producing cells. The serum lipoprotein, high-density lipoprotein (HDL) has been shown to accomplish this function, whereas low-density lipoproteins are ineffective. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298ad79a460e25c12869cef68fca168f
https://doi.org/10.1016/j.atherosclerosis.2004.08.039
https://doi.org/10.1016/j.atherosclerosis.2004.08.039
Publikováno v:
Life Sciences, Vol. 112, No 1-2 (2014) pp. 68-73
LIFE SCIENCES
LIFE SCIENCES
Aims The synthetic counterparts of serum high density lipoproteins (HDL; reconstituted HDL, reHDL) are assuming increasing importance as a therapeutic vector. They circulate not only in blood, but also outside the vascular compartment giving access t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d7de43c1eb474ddea75a69fd8327524
https://archive-ouverte.unige.ch/unige:74190
https://archive-ouverte.unige.ch/unige:74190
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 4, Pp 528-535 (2001)
There are considerable variations in serum concentrations of the high density lipoprotein (HDL)-associated enzyme, paraoxonase (PON), which is an important determinant of the antioxidant capacity of HDL. The present study examined the hypothesis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986659e8886ac607c6ea258637ee6854
https://doi.org/10.1016/s0022-2275(20)31161-5
https://doi.org/10.1016/s0022-2275(20)31161-5
Publikováno v:
Free Radical Biology and Medicine, Vol. 50, No 1 (2011) pp. 102-9
Free radical biology & medicine
Free radical biology & medicine
Paraoxonase-1 (PON1) is a high-density lipoprotein (HDL)-associated serum enzyme thought to make a major contribution to the antioxidant capacity of the lipoprotein. In previous studies, we proposed that HDL promoted PON1 secretion by transfer of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6643d07be7160be0680b8d6c0a77f79e
https://pubmed.ncbi.nlm.nih.gov/20850524
https://pubmed.ncbi.nlm.nih.gov/20850524