Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sara D. Pugh"'
Autor:
Sara D Pugh, David A MacDougall, Shailesh R Agarwal, Robert D Harvey, Karen E Porter, Sarah Calaghan
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106905 (2014)
The number of people taking statins is increasing across the globe, highlighting the importance of fully understanding statins' effects on the cardiovascular system. The beneficial impact of statins extends well beyond regression of atherosclerosis t
Externí odkaz:
https://doaj.org/article/dd91de595505428ea0da847f5f3119e5
Publikováno v:
Journal of Molecular Biology
Under appropriate conditions, the four-helical Im7 (immunity protein 7) folds from an ensemble of unfolded conformers to a highly compact native state via an on-pathway intermediate. Here, we investigate the unfolded, intermediate, and native states
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed803244e70432fd9e4c2cf1a05b231c
https://doi.org/10.1016/j.jmb.2010.02.048
https://doi.org/10.1016/j.jmb.2010.02.048
Autor:
David A. MacDougall, Sarah Calaghan, Karen E. Porter, Sara D. Pugh, Robert D. Harvey, Shailesh R. Agarwal
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 9, p e106905 (2014)
PLoS ONE, Vol 9, Iss 9, p e106905 (2014)
The number of people taking statins is increasing across the globe, highlighting the importance of fully understanding statins' effects on the cardiovascular system. The beneficial impact of statins extends well beyond regression of atherosclerosis t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1da1e9c2ee6dd20a5954dbe1a3df15
https://doi.org/10.1371/journal.pone.0106905
https://doi.org/10.1371/journal.pone.0106905
Publikováno v:
Biophysical Journal. 98:721a
Pleiotropic effects of statins on endothelial cells, vascular smooth muscle cells and fibroblasts are well-established and contribute to reduced cardiovascular morbidity and mortality. Here we test whether these effects extend to the cardiomyocyte. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fb074b5839425e1caa9419df6687dc
https://doi.org/10.1016/j.bpj.2009.12.3947
https://doi.org/10.1016/j.bpj.2009.12.3947
Autor:
Sara D. Pugh, Sarah Calaghan, David A. MacDougall, Robert D. Harvey, Shailesh R. Agarwal, Richard Tyser
Publikováno v:
Journal of Molecular and Cellular Cardiology
β1-Adrenergic receptors (β1ARs) and E-type prostaglandin receptors (EPRs) both produce compartmentalized cAMP responses in cardiac myocytes. The role of cholesterol-dependent lipid rafts in producing these compartmentalized responses was investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d7f92f5e178dd401e218bb86247451