Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sara Calafate"'
Autor:
Pranav Preman, Julia TCW, Sara Calafate, An Snellinx, Maria Alfonso-Triguero, Nikky Corthout, Sebastian Munck, Dietmar Rudolf Thal, Alison M Goate, Bart De Strooper, Amaia M Arranz
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-18 (2021)
Abstract Background Increasing evidence for a direct contribution of astrocytes to neuroinflammatory and neurodegenerative processes causing Alzheimer’s disease comes from molecular and functional studies in rodent models. However, these models may
Externí odkaz:
https://doaj.org/article/6f6aad58ba3e4327a615115ca66accb3
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 931-940 (2016)
Tau pathology propagates within synaptically connected neuronal circuits, but the underlying mechanisms are unclear. BIN1-amphiphysin2 is the second most prevalent genetic risk factor for late-onset Alzheimer’s disease. In diseased brains, the BIN1
Externí odkaz:
https://doaj.org/article/3f459f942dbf4e278f7146040287a034
Autor:
Sara Calafate, Arjan Buist, Katarzyna Miskiewicz, Vinoy Vijayan, Guy Daneels, Bart de Strooper, Joris de Wit, Patrik Verstreken, Diederik Moechars
Publikováno v:
Cell Reports, Vol 11, Iss 8, Pp 1176-1183 (2015)
Accumulation of insoluble Tau protein aggregates and stereotypical propagation of Tau pathology through the brain are common hallmarks of tauopathies, including Alzheimer’s disease (AD). Propagation of Tau pathology appears to occur along connected
Externí odkaz:
https://doaj.org/article/159e47c8bd1743aeaadb7455211139fd
Autor:
Julia Tcw, Amaia M. Arranz, Dietmar Rudolf Thal, Bart De Strooper, Pranav Preman, Nikky Corthout, Sara Calafate, An Snellinx, Alison Goate, Maria Alfonso-Triguero, Sebastian Munck
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-18 (2021)
Molecular Neurodegeneration
Molecular Neurodegeneration
BackgroundIncreasing evidence for a direct contribution of astrocytes to neuroinflammatory and neurodegenerative processes causing Alzheimer’s disease comes from molecular and functional studies in rodent models. However, these models may not fully
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8694db7852ed2998191590779db6331f
https://doi.org/10.1186/s13024-021-00487-8
https://doi.org/10.1186/s13024-021-00487-8
Publikováno v:
Revista de Ciência Elementar. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a2420ab90892bffa862a8f99e6a1bda
https://doi.org/10.24927/rce2021.031
https://doi.org/10.24927/rce2021.031
Autor:
Sara Calafate, Luís Calafate
A reflexão e a discussão sobre o papel da especificação genética e da experiência na aquisição de uma função e no desenvolvimento de um indivíduo traduz um debate fascinante e muito atual entre quem trabalha na área do desenvolvimento do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531dbb49f8449363e45f45b6b987d4e3
https://hdl.handle.net/10216/136646
https://hdl.handle.net/10216/136646
Autor:
Alison Goate, An Snellinx, Dietmar Rudolf Thal, Sara Calafate, Bart De Strooper, Julia T.C.W., Amaia M. Arranz, Pranav Preman
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b27bd0e70383e4f8353d81b857a47e02
https://doi.org/10.1002/alz.042678
https://doi.org/10.1002/alz.042678
Autor:
Sara Calafate, Alison Goate, Maria Alfonso-Triguero, Pranav Preman, Bart Destrooper, Nikky Corthout, Dietmar Rudolf Thal, Amaia M. Arranz, Julia Tcw, Sebastian Munck, An Snellinx
Background: Increasing evidence for a direct contribution of astrocytes to neuroinflammatory and neurodegenerative processes causing Alzheimer’s disease comes from molecular studies in rodent models. However, these models may not fully recapitulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90c3370757584bf10e6f79d005c0fcdd
https://doi.org/10.21203/rs.3.rs-112937/v1
https://doi.org/10.21203/rs.3.rs-112937/v1
Autor:
Pranav Preman, Julia TCW, Sara Calafate, An Snellinx, Maria Alfonso-Triguero, Nikky Corthout, Sebastian Munck, Dietmar Rudolf Thal, Alison M Goate, Bart De Strooper, Amaia M Arranz
BackgroundIncreasing evidence for a direct contribution of astrocytes to neuroinflammatory and neurodegenerative processes causing Alzheimer’s disease comes from molecular studies in rodent models. However, these models may not fully recapitulate h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6e951802f197166d40b130f74d2dfca
https://lirias.kuleuven.be/handle/20.500.12942/696758
https://lirias.kuleuven.be/handle/20.500.12942/696758
Autor:
Kurt R. Brunden, Bryan Zoll, Diederik Moechars, Alex Crowe, Virginia M.-Y. Lee, Joshua P. Daniels, Frederik Stevenaert, Alberto M. Soares, Kathleen Callaerts, Sara Calafate, Jing L. Guo, Arjan Buist
Publikováno v:
Journal of Biological Chemistry. 291:13175-13193
Filamentous tau aggregates, the hallmark lesions of Alzheimer disease (AD), play key roles in neurodegeneration. Activation of protein degradation systems has been proposed to be a potential strategy for removing pathological tau, but it remains uncl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::902e85fa97875274a152f24d958325a8
https://doi.org/10.1074/jbc.m115.712083
https://doi.org/10.1074/jbc.m115.712083