Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sara C. Silva-Reis"'
Autor:
Ana P. Spencer, Marília Torrado, Beatriz Custódio, Sara C. Silva-Reis, Sofia D. Santos, Victoria Leiro, Ana P. Pêgo
Publikováno v:
Pharmaceutics, Vol 12, Iss 2, p 192 (2020)
Central nervous system (CNS) disorders encompass a vast spectrum of pathological conditions and represent a growing concern worldwide. Despite the high social and clinical interest in trying to solve these pathologies, there are many challenges to br
Externí odkaz:
https://doaj.org/article/2a8b0faea1814fda96f0ab00064e36cb
Autor:
Sara C. Silva-Reis, Ivo E. Sampaio-Dias, Vera M. Costa, Xavier Cruz Correia, Hugo F. Costa-Almeida, Xerardo García-Mera, José E. Rodríguez-Borges
Publikováno v:
ACS Chemical Neuroscience. 14:554-572
Autor:
Hugo F. Costa-Almeida, Sara C. Silva-Reis, Ivo Dias, Xavier C. Correia, Beatriz L. Pires-Lima
Publikováno v:
Synthesis. 54:2031-2036
A convenient synthetic protocol for the unprecedented N-hydroxylation of proline residue in Melanostatin (MIF-1) neuropeptide is reported. This methodology is grounded on the incorporation of N-(cyanoethyl)prolyl residue followed by on-site oxidation
Autor:
Ivo E. Sampaio-Dias, José E. Rodríguez-Borges, A. Catarina V. D. dos Santos, Sara C. Silva-Reis, Xerardo García-Mera
Publikováno v:
New Journal of Chemistry. 44:21049-21063
Neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, are a class of heterogeneous pathologies of the central nervous system (CNS) affecting millions of people worldwide. CNS-related pathologies represent a global health burden in
Autor:
Ivo E. Sampaio-Dias, Xavier Cruz Correia, Sara C. Silva-Reis, Beatriz L. Pires-Lima, Hugo F. Costa-Almeida, Xerardo García-Mera, José E. Rodríguez-Borges
Publikováno v:
Proceedings of 7th International Electronic Conference on Medicinal Chemistry.
Autor:
Ivo E. Sampaio-Dias, Sara C. Silva-Reis, Miguel Santejo, Márcia A. Liz, Cristina Alcoholado, Manuel Algarra, Xerardo García-Mera, José E. Rodríguez-Borges
Publikováno v:
Proceedings of 7th International Electronic Conference on Medicinal Chemistry.
Autor:
Ivo E. Sampaio-Dias, Miguel Santejo, José E. Rodríguez-Borges, Cristina Alcoholado, Manuel Algarra, Sara C. Silva-Reis, Xerardo García-Mera, Márcia A. Liz
Publikováno v:
ACS chemical neuroscience. 12(19)
Neurodegenerative disorders of the central nervous system are a class of heterogeneous pathologies affecting millions of people worldwide and represent a global health burden in developed and developing countries. Without restorative treatments curre
Autor:
Ivo E. Sampaio-Dias, José Brea, Sara C. Silva-Reis, Xerardo García-Mera, Manuel Algarra, M. Isabel Loza, José E. Rodríguez-Borges, Carla S. Alves
Publikováno v:
ACS Chemical Neuroscience. 10:3690-3702
This work describes the synthesis and pharmacological evaluation of picolinoyl-based peptidomimetics of melanocyte stimulating hormone release inhibiting factor 1 (MIF-1) as dopamine modulating agents. Eight novel peptidomimetics were tested for thei
Autor:
José E. Rodríguez-Borges, Luís Pinto da Silva, Sara C. Silva-Reis, Ivo E. Sampaio-Dias, Xerardo García-Mera, Miguel A. Maestro
Publikováno v:
Organic Chemistry Frontiers. 6:3540-3554
Herein we present a new synthesis methodology for the transprotection of the 1-phenylethyl protected tertiary amines to tert-butyloxycarbonyl (Boc) derivatives under exocyclic N–C hydrogenolysis catalyzed by Pd/C. We provide mechanistic insights in
Autor:
José E. Rodríguez-Borges, Sara C. Silva-Reis, Ivo E. Sampaio-Dias, Xerardo García-Mera, Beatriz Lopes P. Lima
Publikováno v:
Proceedings of 6th International Electronic Conference on Medicinal Chemistry.