A Polyclonal Antibody against a Burkholderia cenocepacia OmpA-like Protein Strongly Impairs Pseudomonas aeruginosa and B. multivorans Virulence

Autor: António M. M. Seixas, Sara C. Gomes, Carolina Silva, Leonilde M. Moreira, Jorge H. Leitão, Sílvia A. Sousa

Publikováno v: Vaccines, Vol 12, Iss 2, p 207 (2024)

Despite advances in therapies, bacterial chronic respiratory infections persist as life-threatening to patients suffering from cystic fibrosis (CF). Pseudomonas aeruginosa and bacteria of the Burkholderia cepacia complex are among the most difficult

Externí odkaz: https://doaj.org/article/3e7cd2f606f648ac88fa93171a06529b

Intravitreal Therapy Against the Complement Factor C5 Prevents Retinal Degeneration in an Experimental Autoimmune Glaucoma Model

Autor: Sabrina Reinehr, Sara C. Gomes, Caroline J. Gassel, M. Ali Asaad, Gesa Stute, Marc Schargus, H. Burkhard Dick, Stephanie C. Joachim

Publikováno v: Frontiers in Pharmacology, Vol 10 (2019)

In glaucoma, studies revealed an involvement of the complement system. In an experimental autoimmune glaucoma model, immunization with an optic nerve homogenate antigen (ONA) led to retinal ganglion cell (RGC) loss, while intraocular pressure (IOP) r

Externí odkaz: https://doaj.org/article/ee31bee25b1c41e0ba22a5bb4cc68d9b

A Polyclonal Antibody Raised against the Burkholderia cenocepacia OmpA-like Protein BCAL2645 Impairs the Bacterium Adhesion and Invasion of Human Epithelial Cells In Vitro

Autor: Leonilde M. Moreira, Jorge H. Leitão, Joana R. Feliciano, Sara C. Gomes, António M M Seixas, Mirela R. Ferreira, Sílvia A. Sousa

Publikováno v: Biomedicines, Vol 9, Iss 1788, p 1788 (2021)
CIÊNCIAVITAE
Biomedicines
Biomedicines; Volume 9; Issue 12; Pages: 1788

Respiratory infections by bacteria of the Burkholderia cepacia complex (Bcc) remain a life threat to cystic fibrosis (CF) patients, due to the faster lung function decline and the absence of effective eradication strategies. Immunotherapies are regar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e3befcef24340d24d63e24ac754d93
https://www.mdpi.com/2227-9059/9/12/1788

Molecular and functional characterization of grapevine NIPs through heterologous expression in aqy-null Saccharomyces cerevisiae

Autor: Farzana Sabir, Catarina Prista, Sara C. Gomes, Maria C. Loureiro-Dias, Graça Soveral

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
International Journal of Molecular Sciences, Vol 21, Iss 2, p 663 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 2

Plant Nodulin 26-like Intrinsic Proteins (NIPs) are multifunctional membrane channels of the Major Intrinsic Protein (MIP) family. Unlike other homologs, they have low intrinsic water permeability. NIPs possess diverse substrate selectivity, ranging

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7b09974be90c167a21232c3b7a6298

Intravitreal Therapy Against the Complement Factor C5 Prevents Retinal Degeneration in an Experimental Autoimmune Glaucoma Model

Autor: Caroline J. Gassel, Sabrina Reinehr, M. Ali Asaad, Gesa Stute, Sara C. Gomes, Stephanie C. Joachim, H. Burkhard Dick, Marc Schargus

Publikováno v: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 10 (2019)

In glaucoma, studies revealed an involvement of the complement system. In an experimental autoimmune glaucoma model, immunization with an optic nerve homogenate antigen (ONA) led to retinal ganglion cell (RGC) loss, while intraocular pressure (IOP) r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66ba80fe01d453d6141da92c8b3bc48
https://pubmed.ncbi.nlm.nih.gov/31849650