Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sara Broski"'
Autor:
Steven Finkbeiner, Neal A.L. Cody, Kari L. Server, Ashkan Javaherian, Eric Lécuyer, Sara Broski, Gene W. Yeo, Amit Fulzele, Sebastian Markmiller, Shashank Sathe, Eric J. Bennett, Thai B. Nguyen
Publikováno v:
SSRN Electronic Journal.
Neurodegeneration-associated mutations affect the dynamics of transient cytoplasmic stress granules (SGs). However, it is unclear if and how aberrant SG behavior is linked to the downstream formation of protein aggregates and other molecular defects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6961e7b75ad470298686c64e891a78fb
https://doi.org/10.2139/ssrn.3721719
https://doi.org/10.2139/ssrn.3721719
Autor:
Sebastian Markmiller, Shashank Sathe, Eric Lécuyer, Steven Finkbeiner, Kari L. Server, Ashkan Javaherian, Neal A.L. Cody, Eric J. Bennett, Sara Broski, Gene W. Yeo, Thai B. Nguyen, Amit Fulzele
Publikováno v:
Cell Reports. 36:109685
Persistent cytoplasmic aggregates containing RNA binding proteins (RBPs) are central to the pathogenesis of late-onset neurodegenerative disorders such as amyotrophic lateral sclerosis (ALS). These aggregates share components, molecular mechanisms, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d1a56fd18d6d028b8e0299e20010fe
https://doi.org/10.1016/j.celrep.2021.109685
https://doi.org/10.1016/j.celrep.2021.109685
Autor:
Gene W. Yeo, Manuel Ares, Katannya Kapeli, Seung J. Chun, Peter Freese, Harrison Wang, Hong Joo Kim, Stephanie C. Huelga, Rea M. Lardelli, Balaji Sundararaman, Sara Broski, Layla Fijany, Chelsea Gelboin-Burkhart, Frank Rigo, Jens Lykke-Andersen, Steven Finkbeiner, Ranjan Batra, J. Paul Taylor, Karen Ling, Eric L. Van Nostrand, Ashkan Javaherian, Christopher B. Burge, Fernando J. Martinez, C. Frank Bennett, Gabriel A. Pratt, Julia K. Nussbacher, John Paul Donohue
Publikováno v:
Neuron. 92:780-795
HnRNPA2B1 encodes an RNA binding protein associated with neurodegeneration. However, its function in the nervous system is unclear. Transcriptome-wide crosslinking and immunoprecipitation in mouse spinal cord discover UAGG motifs enriched within ∼2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae614d90797d6b22ad621845b82ea1d
https://doi.org/10.1016/j.neuron.2016.09.050
https://doi.org/10.1016/j.neuron.2016.09.050