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Akademický článek

SecA localization and SecA-dependent secretion occurs at new division septa in group B Streptococcus.

Autor: Sara Brega, Elise Caliot, Patrick Trieu-Cuot, Shaynoor Dramsi

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e65832 (2013)

Exported proteins of Streptococcus agalactiae (GBS), which include proteins localized to the bacterial surface or secreted into the extracellular environment, are key players for commensal and pathogenic interactions in the mammalian host. These prot

Externí odkaz: https://doaj.org/article/a44c1588f8044d3e8233f2ee9241f51a

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Akademický článek

The GBS PI-2a pilus is required for virulence in mice neonates.

Autor: Salvatore Papasergi, Sara Brega, Michel-Yves Mistou, Arnaud Firon, Virginie Oxaran, Ron Dover, Giuseppe Teti, Yechiel Shai, Patrick Trieu-Cuot, Shaynoor Dramsi

Publikováno v: PLoS ONE, Vol 6, Iss 4, p e18747 (2011)

BACKGROUND:Streptococcus agalactiae (Group B Streptococcus) is a leading cause of sepsis and meningitis in newborns. Most bacterial pathogens, including gram-positive bacteria, have long filamentous structures known as pili extending from their surfa

Externí odkaz: https://doaj.org/article/6493723e7bff427a9b281dd4882e1410

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Plasmodium bergheihistamine-releasing factor favours liver-stage development via inhibition of IL-6 production and associates with a severe outcome of disease

Autor: Claudia Demarta-Gatsi, Leanna Smith, Sara Brega, Salaheddine Mécheri, Roger Peronet, Sabine Thiberge, Robert Ménard, Adeline Porcherie, Rogerio Amino, Karine Ronce, Cedric Mathieu

Publikováno v: Cellular Microbiology. 17:542-558

Summary Plasmodium spp., which causes malaria, produces a histamine-releasing factor (HRF), an orthologue of mammalian HRF. Histamine-releasing factor produced by erythrocytic stages of the parasite is thought to play a role in the pathogenesis of se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::005fad6ed334b6e59128ae19752310b6
https://doi.org/10.1111/cmi.12382

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Real-Time PCR for Dihydrofolate Reductase Gene Single-Nucleotide Polymorphisms in Plasmodium vivax Isolates

Autor: Rachanee Udomsangpetch, Carlo Severini, Inge Sutanto, Sara Brega, François Peyron, Stéphane Picot, Paul Ruckert, Frédérique de Monbrison

Publikováno v: Antimicrobial Agents and Chemotherapy. 48:2581-2587

Mutations in the dhfr gene of Plasmodium vivax ( pvdhfr ) are associated with resistance to the antifolate antimalarial drugs. Polymorphisms in the pvdhfr gene were assessed by hybridization probe technology on the LightCycler instrument with 134 P.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::018fc05e41f0c892a401655cad5954d1
https://doi.org/10.1128/aac.48.7.2581-2587.2004

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Plasmodium berghei histamine-releasing factor favours liver-stage development via inhibition of IL-6 production and associates with a severe outcome of disease

Autor: Cédric, Mathieu, Claudia, Demarta-Gatsi, Adeline, Porcherie, Sara, Brega, Sabine, Thiberge, Karine, Ronce, Leanna, Smith, Roger, Peronet, Rogerio, Amino, Robert, Ménard, Salaheddine, Mécheri

Publikováno v: Cellular microbiology. 17(4)

Plasmodium spp., which causes malaria, produces a histamine-releasing factor (HRF), an orthologue of mammalian HRF. Histamine-releasing factor produced by erythrocytic stages of the parasite is thought to play a role in the pathogenesis of severe mal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8597cc295bbd3edec1c6acc0f8735f4
https://pubmed.ncbi.nlm.nih.gov/25329441

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The GBS PI-2a pilus is required for virulence in mice neonates

Autor: Patrick Trieu-Cuot, Ron Saar Dover, Salvatore Papasergi, Arnaud Firon, Virginie Oxaran, Michel-Yves Mistou, Giuseppe Teti, Sara Brega, Shaynoor Dramsi, Yechiel Shai

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2010, 6 (4), pp.e18747. ⟨10.1371/journal.pone.0018747⟩
Plos One 4 (6), . (2011)
PLoS ONE, Vol 6, Iss 4, p e18747 (2011)
PLoS ONE, 2010, 6 (4), pp.e18747. ⟨10.1371/journal.pone.0018747⟩

Background: Streptococcus agalactiae (Group B Streptococcus) is a leading cause of sepsis and meningitis in newborns. Most bacterial pathogens, including gram-positive bacteria, have long filamentous structures known as pili extending from their surf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f531629bd4ce7c66bfca481806a040
https://hal.archives-ouvertes.fr/hal-01190509

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Molecular Dissection of the secA2 Locus of Group B Streptococcus Reveals that Glycosylation of the Srr1 LPXTG Protein Is Required for Full Virulence

Autor: Claire Poyart, Michel-Yves Mistou, Sara Brega, Shaynoor Dramsi, Patrick Trieu-Cuot

Publikováno v: Journal of Bacteriology
Journal of Bacteriology, 2009, 191 (13), pp.4195-4206. ⟨10.1128/JB.01673-08⟩
Journal of Bacteriology, American Society for Microbiology, 2009, 191 (13), pp.4195-4206. ⟨10.1128/JB.01673-08⟩

In streptococci, the secA2 locus includes genes encoding the following: (i) the accessory Sec components (SecA2, SecY2, and at least three accessory secretion proteins), (ii) two essential glycosyltranferases (GTs) (GtfA and GtfB), (iii) a variable n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b70a73bf010a87bab8ada48c43134d2
https://hal-pasteur.archives-ouvertes.fr/pasteur-03262499

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Molecular markers of in vivo Plasmodium vivax resistance to amodiaquine plus sulfadoxine-pyrimethamine: mutations in pvdhfr and pvmdr1

Autor: Sara Brega, Ivo Müller, Laetitia Barbollat, Jutta Marfurt, Albert Sie, Blaise Genton, Frédérique de Monbrison, Stéphane Picot, Hans-Peter Beck, John C. Reeder, Mary Goroti

Publikováno v: The Journal of infectious diseases. 198(3)

Background. Molecular markers for sulfadoxine-pyrimethamine (SP) resistance in Plasmodium vivax have been reported. However, data on the molecular correlates involved in the development of resistance to 4-aminoquinolines and their association with th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efcd7d86511aaad88832d4184bcb3b2
https://pubmed.ncbi.nlm.nih.gov/18582193

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Identification of the Plasmodium vivax mdr-like gene (pvmdr1) and analysis of single-nucleotide polymorphisms among isolates from different areas of endemicity

Autor: Luigi Gradoni, Sara Brega, Rachanee Udomsangpetch, Carlo Severini, Benoît Meslin, Frédérique de Monbrison, Stéphane Picot, François Peyron, Inge Sutanto

Publikováno v: The Journal of infectious diseases. 191(2)

Because of the lack of methods for continuous in vitro culture of Plasmodium vivax, little is known about drug-resistance mechanisms in this malaria-causing parasite. Therefore, identification of all the genes potentially involved in drug resistance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd19030100e5ad26da7ef289b3564493
https://pubmed.ncbi.nlm.nih.gov/15609238

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Absence of nucleotide polymorphism in a Plasmodium vivax multidrug resistance gene after failure of mefloquine prophylaxis in French Guyana

Autor: V. Cheminel, F. de Monbrison, Stéphane Picot, François Peyron, Sara Brega, P. Gérome, G. Velut

Publikováno v: Transactions of the Royal Society of Tropical Medicine and Hygiene. 99(3)

Vivax malaria is widespread and resistance has been described for chloroquine and sulfadoxine-pyrimethamine. We report on evidence of failure of mefloquine prophylaxis in a French soldier who contracted Plasmodium vivax in French Guyana, South Americ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c613a9a2baad15e616f8082e74de6f9a
https://pubmed.ncbi.nlm.nih.gov/15653127

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