Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sara Bologna"'
Autor:
Giovanni Bellomo, Silvia Paciotti, Luis Concha-Marambio, Domenico Rizzo, Anna Lidia Wojdaƚa, Davide Chiasserini, Leonardo Gatticchi, Linda Cerofolini, Stefano Giuntini, Chiara Maria Giulia De Luca, Yihua Ma, Carly M. Farris, Giuseppe Pieraccini, Sara Bologna, Marta Filidei, Enrico Ravera, Moreno Lelli, Fabio Moda, Marco Fragai, Lucilla Parnetti, Claudio Luchinat
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-24 (2023)
Abstract Background Aggregation of α-synuclein (α-syn) is a prominent feature of Parkinson’s disease (PD) and other synucleinopathies. Currently, α-syn seed amplification assays (SAAs) using cerebrospinal fluid (CSF) represent the most promising
Externí odkaz:
https://doaj.org/article/8a0abc545ac346ba9dc7517cc43c701f
Autor:
Giovanni Bellomo, Silvia Paciotti, Luis Concha-Marambio, Domenico Rizzo, Leonardo Gatticchi, Linda Cerofolini, Stefano GIuntini, Chiara Maria Giulia De Luca, Yihua Ma, Carly M. Farris, Giuseppe Pieraccini, Sara Bologna, Marta Filidei, Enrico Ravera, Moreno Lelli, Fabio Moda, Marco Fragai, Lucilla Parnetti, Claudio Luchinat
Background: Aggregation of α-synuclein (α-syn) is a prominent feature of Parkinson’s disease (PD) and other synucleinopathies. In these diseases, the extracellular spreading of misfolded α-syn significantly contributes to the cell-to-cell propag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e61d2fdf3b23a291c67faa2f29a6c6a
https://doi.org/10.21203/rs.3.rs-2001732/v1
https://doi.org/10.21203/rs.3.rs-2001732/v1
Autor:
Annett Böddrich, Domenico Rizzo, Iryna Benilova, Bettina Purfürst, Sara Bologna, Claudio Luchinat, Linda Cerofolini, Bart De Strooper, Leonardo Gonnelli, Gianluca Gallo, Erich E. Wanker, Marco Fragai, Thomas Wiglenda, Enrico Ravera, Magdalena Korsak
Publikováno v:
Chemical Communications
Recent structural studies show distinct morphologies for the fibrils of Aβ(1-42) and Aβ(1-40), which are believed not to co-fibrillize. We describe here a novel, structurally-uniform 1 : 1 mixed fibrillar species, which differs from both pure fibri
Autor:
Linda Cerofolini, Leonardo Gatticchi, Giovanni Bellomo, Sara Bologna, Lucilla Parnetti, Enrico Ravera, Claudio Luchinat, Silvia Paciotti, Marco Fragai
Publikováno v:
The journal of physical chemistry. B. 123(20)
α-Synuclein (α-syn) is found to be naturally present in biofluids such as cerebrospinal fluid (CSF) and serum. Human serum albumin (HSA) is the most abundant protein found in these biofluids, which, beyond transporting hormones and drugs, also exer
Autor:
Vincenzo Villanacci, Vittorio Baldini, Gabrio Bassotti, Giovanni Casella, C. Di Bella, M. Piatti, Elisabetta Antonelli, Sara Bologna, E. Di Marco
Publikováno v:
Techniques in Coloproctology. 17:497-500
Thromboembolic complications have been reported in patients with Crohn's disease. Among the contributing factors, hyperhomocysteinemia has been described, although controversial data exist. The aim of our study was to assess the incidence of hyperhom
Autor:
Barbara Campanini, Sara Bologna, Samanta Raboni, Stefano Bettati, Elena Grandi, Stefania Abbruzzetti, Andrea Mozzarelli, Cristiano Viappiani
Publikováno v:
Journal of the American Chemical Society. 127:626-635
We have used a nanosecond pH-jump technique, coupled with simultaneous transient absorption and fluorescence emission detection, to characterize the dynamics of the acid-induced spectral changes in the GFPmut2 chromophore. Disappearance of the absorb
Publikováno v:
Surgical endoscopy. 28(1)
We read with interest the recent article by Tan et al. [1], claiming that the use of psychotropic drugs causes changes in colonic architecture. We strongly disagree with this concept, which may lead to inappropriate modifications of therapeutic sched
Publikováno v:
BMC Gastroenterology
Background Constipation severity is often defined by symptoms including feelings of complete evacuation, straining, stool frequency and consistency. These descriptors are mostly obtained in the absence of laxative use. For many constipated patients l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6557ff90798b2436ac9a8cd146d88873
http://hdl.handle.net/11391/862898
http://hdl.handle.net/11391/862898
Autor:
Stefano Bettati, Sara Bologna, Fabio Cannone, Barbara Campanini, Andrea Mozzarelli, Alberto Diaspro, Giuseppe Chirico
The unfolding and refolding kinetics of >600 single GFPmut2 molecules, entrapped in wet nanoporous silica gels, were followed by monitoring simultaneously the fluorescence emission of the anionic and neutral state of the chromophore, primed by two-ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9a39a47df19aecf7c5c30c1be55df2
http://hdl.handle.net/10281/2278
http://hdl.handle.net/10281/2278
Autor:
Sara Bologna, Vittorio Pellegrini, Fabio Cannone, Maddalena Collini, Fabio Beltram, Alberto Diaspro, G. Chirico
We report the two-photon excitation and emission of a recently developed green fluorescent protein (GFP) mutant, E2GFP. Two main excitation bands are found at 780 and 870 nm. Blinking and irreversible and reversible bleaching were observed. Fluoresce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94458cc3667e0e6c70c97487408494a7
http://hdl.handle.net/10281/14970
http://hdl.handle.net/10281/14970