Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sara Björk Sigurdardóttir"'
Autor:
Diána Hudecz, Sara Björk Sigurdardóttir, Sarah Christine Christensen, Casper Hempel, Andrew J Urquhart, Thomas Lars Andresen, Morten S Nielsen
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0249686 (2021)
The blood-brain barrier (BBB) is one of the main obstacles for therapies targeting brain diseases. Most macromolecules fail to pass the tight BBB, formed by brain endothelial cells interlinked by tight junctions. A wide range of small, lipid-soluble
Externí odkaz:
https://doaj.org/article/922698fa4c0a47eb9b69cb886bed49d9
Autor:
Andrew J. Urquhart, Sara Björk Sigurdardóttir, Sarah Christine Christensen, Thomas Lars Andresen, Morten Nielsen, Diána Hudecz, Casper Hempel
Publikováno v:
Hudecz, D, Sigurdardóttir, S B, Christensen, S C, Hempel, C, Urquhart, A J, Andresen, T L & Nielsen, M S 2021, ' Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells ', PLOS ONE, vol. 16, no. 4, e0249686 . https://doi.org/10.1371/journal.pone.0249686
Hudecz, D, Sigurdardóttir, S B, Christensen, S C, Hempel, C, Urquhart, A J, Andresen, T L & Nielsen, M S 2021, ' Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells ', PLOS ONE, vol. 16, e0249686 . https://doi.org/10.1371/journal.pone.0249686
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249686 (2021)
Hudecz, D, Sigurdardóttir, S B, Christensen, S C, Hempel, C, Urquhart, A J, Andresen, T L & Nielsen, M S 2021, ' Two peptides targeting endothelial receptors are internalized into murine brain endothelial cells ', PLOS ONE, vol. 16, e0249686 . https://doi.org/10.1371/journal.pone.0249686
PLoS ONE
PLoS ONE, Vol 16, Iss 4, p e0249686 (2021)
The blood-brain barrier (BBB) is one of the main obstacles for therapies targeting brain diseases. Most macromolecules fail to pass the tight BBB, formed by brain endothelial cells interlinked by tight junctions. A wide range of small, lipid-soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa30e19fe0204ed8693055ee68d52673
https://pure.au.dk/portal/da/publications/two-peptides-targeting-endothelial-receptors-are-internalized-into-murine-brain-endothelial-cells(c5af39a7-7a79-4414-9886-948bc7fdee5c).html
https://pure.au.dk/portal/da/publications/two-peptides-targeting-endothelial-receptors-are-internalized-into-murine-brain-endothelial-cells(c5af39a7-7a79-4414-9886-948bc7fdee5c).html
Autor:
Rasmus P. Clausen, Claus H. Jensen, Sara Björk Sigurdardóttir, Kenneth T. Kongstad, David E. Gloriam, Petrine Wellendorph, Mia Nittegaard-Nielsen, Christina Birkedahl Falk-Petersen, Francesco Bavo, Yongsong Tian, Jan Kehler, Kasper Harpsøe, Jacob Krall, Stine B. Vogensen, Bente Frølund, Anne S. Haugaard
Publikováno v:
Journal of Medicinal Chemistry. 60:9022-9039
γ-hydroxybutyric acid (GHB) is a neuroactive substance with specific high-affinity binding sites. To facilitate target identification and ligand optimization, we herein report a comprehensive structure-affinity relationship study for novel ligands t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::371f91bb7a8a910a778dba45c5ffc706
https://doi.org/10.1021/acs.jmedchem.7b01351
https://doi.org/10.1021/acs.jmedchem.7b01351