Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Sara Bitar"'
Autor:
Sara Bitar, Timo Baumann, Christopher Weber, Majd Abusaada, Liliana Rojas-Charry, Patrick Ziegler, Thomas Schettgen, Isabella Eva Randerath, Vivek Venkataramani, Bernhard Michalke, Eva-Maria Hanschmann, Giuseppe Arena, Rejko Krueger, Li Zhang, Axel Methner
Publikováno v:
eLife, Vol 13 (2024)
Parkinson’s disease (PD) is characterized by the progressive loss of dopaminergic neurons in the substantia nigra of the midbrain. Familial cases of PD are often caused by mutations of PTEN-induced kinase 1 (PINK1) and the ubiquitin ligase Parkin,
Externí odkaz:
https://doaj.org/article/ddd37b7d5e23475c81a453ad7fd792d8
Autor:
Christina Wolf, Alireza Pouya, Sara Bitar, Annika Pfeiffer, Diones Bueno, Liliana Rojas-Charry, Sabine Arndt, David Gomez-Zepeda, Stefan Tenzer, Federica Dal Bello, Caterina Vianello, Sandra Ritz, Jonas Schwirz, Kristina Dobrindt, Michael Peitz, Eva-Maria Hanschmann, Pauline Mencke, Ibrahim Boussaad, Marion Silies, Oliver Brüstle, Marta Giacomello, Rejko Krüger, Axel Methner
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
GDAP1 mutations effect Charcot-Marie-Tooth disease 4A by inhibiting the pyruvate dehydrogenase complex and restricting mitochondrial localization of dynamin-related protein 1 through alterations of the actin cytoskeleton.
Externí odkaz:
https://doaj.org/article/9641c18a790e4040bf3d22838d1e06f0
Autor:
Kanupriya R. Daga, Andrew M. Larey, Maria G. Morfin, Kailin Chen, Sara Bitarafan, Jana M. Carpenter, Hannah M. Hynds, Kelly M. Hines, Levi B. Wood, Ross A. Marklein
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-21 (2024)
Abstract Background Mesenchymal stromal cell derived extracellular vesicles (MSC-EVs) are a promising therapeutic for neuroinflammation. MSC-EVs can interact with microglia, the resident immune cells of the brain, to exert their immunomodulatory effe
Externí odkaz:
https://doaj.org/article/ed07ae149d72409faf0f21728dc5d06e
Autor:
Alyssa F. Pybus, Sara Bitarafan, Rowan O. Brothers, Alivia Rohrer, Arushi Khaitan, Felix Rivera Moctezuma, Kareena Udeshi, Brae Davies, Sydney Triplett, Martin N. Griffin, Eric B. Dammer, Srikant Rangaraju, Erin M. Buckley, Levi B. Wood
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Repetitive mild traumatic brain injuries (rmTBI) sustained within a window of vulnerability can result in long term cognitive deficits, depression, and eventual neurodegeneration associated with tau pathology, amyloid beta (Aβ) plaques, gli
Externí odkaz:
https://doaj.org/article/33fb43db821e412cb4a51344d8ea1517
Autor:
Mohamed Noureldein, Rashad Nawfal, Sara Bitar, Scott S. Maxwell, Ishant Khurana, Hala Kfoury Kassouf, Fadlo R. Khuri, Assam El-Osta, Assaad A. Eid
Publikováno v:
Cellular and molecular life sciences : CMLS. 79(9)
Diabetes changes the host microbiota, a condition known as dysbiosis. Dysbiosis is an important factor for the pathogenesis of diabetes and colorectal cancer (CRC). We aimed at identifying the microbial signature associated with diabetes and CRC; and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e73ebd71e5a8f9a86635b5c94a256038
https://pubmed.ncbi.nlm.nih.gov/36040503
https://pubmed.ncbi.nlm.nih.gov/36040503
Autor:
Annika Pfeiffer, Eva-Maria Hanschmannn, Jonas Schwirz, Sara Bitar, Ibrahim Boussaad, Oliver Brüstle, Kristina Dobrindt, Caterina Vianello, Diones Caeran Bueno, Michael Peitz, Alireza Pouya, Christina Wolf, Stefan Tenzer, Rejko Krüger, Marta Giacomello, Sandra Ritz, Federica Dal Bello, Axel Methner, Sabine Arndt
Charcot-Marie-Tooth (CMT) disease 4A is an autosomal-recessive polyneuropathy caused by mutations of ganglioside-induced differentiation-associated protein 1 (GDAP1), a putative glutathione transferase, which affects mitochondrial shape and alters ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61d5f3c035b64521c93d8c55a7eb823e
https://doi.org/10.21203/rs.3.rs-209468/v1
https://doi.org/10.21203/rs.3.rs-209468/v1
Autor:
Christina Wolf, Alireza Pouya, Sara Bitar, Annika Pfeiffer, Diones Bueno, Sabine Arndt, Stefan Tenzer, Federica Dal Bello, Caterina Vianello, Sandra Ritz, Jonas Schwirz, Kristina Dobrindt, Michael Peitz, Eva-Maria Hanschmann, Ibrahim Boussaad, Oliver Brüstle, Marta Giacomello, Rejko Krüger, Axel Methner
Charcot-Marie-Tooth (CMT) disease 4A is an autosomal-recessive polyneuropathy caused by mutations of ganglioside-induced differentiation-associated protein 1 (GDAP1), a putative glutathione transferase, which affects mitochondrial shape and alters ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85c2652e4c4416ccc58c62e557cb4e95
https://doi.org/10.1101/2021.03.04.433895
https://doi.org/10.1101/2021.03.04.433895
Publikováno v:
Journal of molecular endocrinology. 64(1)
Diabetic dysbiosis has been described as a novel key player in diabetes and diabetic complications. However, the cellular/molecular alterations associated with dysbiosis remain poorly characterized. For that, control, non-obese type 2 diabetic MKR mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1564dcbef141c413e82adf0beaf2940f
https://pubmed.ncbi.nlm.nih.gov/31770101
https://pubmed.ncbi.nlm.nih.gov/31770101
Autor:
Rima Afifi, Moubadda Assi, Lilian A. Ghandour, Khalil El Asmar, Sara Bitar, Nasser Yassin, Dima Bteddini
Publikováno v:
Journal of religion and health. 59(1)
Alcohol, tobacco and other drug use continue to pose serious public health concerns among youth. Bullying victimization has been identified as a risk factor and religiosity a protective factor for adolescent substance use. No previous research has ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa963e9fb59a271373b9d98d4438122e
https://pubmed.ncbi.nlm.nih.gov/30868336
https://pubmed.ncbi.nlm.nih.gov/30868336
Autor:
Sruti Rayaprolu, Sara Bitarafan, Juliet V. Santiago, Ranjita Betarbet, Sydney Sunna, Lihong Cheng, Hailian Xiao, Ruth S. Nelson, Prateek Kumar, Pritha Bagchi, Duc M. Duong, Annie M. Goettemoeller, Viktor János Oláh, Matt Rowan, Allan I. Levey, Levi B. Wood, Nicholas T. Seyfried, Srikant Rangaraju
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Current isolation-based approaches for cell type-specific proteomics pose several challenges. Here, the authors present an approach for in vivo cell type-specific protein labeling to characterize proteomic differences between neurons and astrocytes i
Externí odkaz:
https://doaj.org/article/0366b13af39b4d438b5baee2a2a9c33d