Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Sara Ballouz"'
Autor:
Chansavath Phetsouphanh, Brendan Jacka, Sara Ballouz, Katherine J. L. Jackson, Daniel B. Wilson, Bikash Manandhar, Vera Klemm, Hyon-Xhi Tan, Adam Wheatley, Anupriya Aggarwal, Anouschka Akerman, Vanessa Milogiannakis, Mitchell Starr, Phillip Cunningham, Stuart G. Turville, Stephen J. Kent, Anthony Byrne, Bruce J. Brew, David R. Darley, Gregory J. Dore, Anthony D. Kelleher, Gail V. Matthews
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID (LC) compared to age and gender matched recovered COVID-19 controls (MC) over 24 mo
Externí odkaz:
https://doaj.org/article/a78592c8ad5f41659f2af285f3a835b0
Autor:
Sara Ballouz, Risa Karakida Kawaguchi, Maria T. Pena, Stephan Fischer, Megan Crow, Leon French, Frank M. Knight, Linda B. Adams, Jesse Gillis
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Genetic and environmental variation are key contributors during organism development, but the influence of minor perturbations or noise is difficult to assess. This study focuses on the stochastic variation in allele-specific expression that
Externí odkaz:
https://doaj.org/article/dbed84c7e6f645c68b35621128732694
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract The use of the human reference genome has shaped methods and data across modern genomics. This has offered many benefits while creating a few constraints. In the following opinion, we outline the history, properties, and pitfalls of the curr
Externí odkaz:
https://doaj.org/article/2c2af69ac9104458a0eafd6f9343414a
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Single cell RNA-sequencing analysis poses challenges in replication due to technical biases and analytic variability among bioinformatics pipelines. Here, Crow et al develop MetaNeighbor for measuring cell-type replication across datasets, and use it
Externí odkaz:
https://doaj.org/article/67fefc8fb1054363be1ef3aa5f0f083c
Autor:
Sara Ballouz, Jesse Gillis
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-14 (2017)
Abstract Background Disagreements over genetic signatures associated with disease have been particularly prominent in the field of psychiatric genetics, creating a sharp divide between disease burdens attributed to common and rare variation, with stu
Externí odkaz:
https://doaj.org/article/d374cd6703a94dc1bbda67cbc6c0bba4
Autor:
Sara Ballouz, Jason Y. Liu, Martin Oti, Bruno Gaeta, Diane Fatkin, Melanie Bahlo, Merridee A. Wouters
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 2, Iss 1, Pp 44-57 (2014)
Abstract Current single‐locus‐based analyses and candidate disease gene prediction methodologies used in genome‐wide association studies (GWAS) do not capitalize on the wealth of the underlying genetic data, nor functional data available from m
Externí odkaz:
https://doaj.org/article/8c07cdbe574c44818d8c501b2e69ce70
Autor:
Sara Ballouz, Jesse Gillis
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 4, p e1004868 (2016)
In addition to detecting novel transcripts and higher dynamic range, a principal claim for RNA-sequencing has been greater replicability, typically measured in sample-sample correlations of gene expression levels. Through a re-analysis of ENCODE data
Externí odkaz:
https://doaj.org/article/6f2d75cee8364de085327598fe4617f0
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0160098 (2016)
The expansion of protein-ligand annotation databases has enabled large-scale networking of proteins by ligand similarity. These ligand-based protein networks, which implicitly predict the ability of neighboring proteins to bind related ligands, may c
Externí odkaz:
https://doaj.org/article/f0d1321045914327982eafb6f5557b24
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 2, p e1000672 (2010)
Genes encoding proteins in a common pathway are often found near each other along bacterial chromosomes. Several explanations have been proposed to account for the evolution of these structures. For instance, natural selection may directly favour gen
Externí odkaz:
https://doaj.org/article/bcc3e0a6a5984372a7f37b0be153df31
Publikováno v:
Genome Research. 32:738-749
The Human Reference Genome serves as the foundation for modern genomic analyses. However, in its present form, it does not adequately represent the vast genetic diversity of the human population. In this study, we explored the consensus genome as a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d5168fd46cb81702ad2c197dc6dd22
https://doi.org/10.1101/gr.275613.121
https://doi.org/10.1101/gr.275613.121