A multi-marker integrative analysis reveals benefits and risks of bariatric surgery

Autor: Simonetta Palleschi, Valeria Guglielmi, Lorenza Nisticò, Carla Ferreri, Claudio Tabolacci, Francesco Facchiano, Egidio Iorio, Alessandro Giuliani, Sonia Brescianini, Emanuela Medda, Corrado Fagnani, Barbara Rossi, Anna Minoprio, Mattea Chirico, Maria Elena Pisanu, Federica Di Nolfo, Paola Fortini, Valeria Simonelli, Sara Baccarini, Serena Laterza, Tiziana Morretti, Ambra Dell’Orso, Federico Manganello, Paolo Gentileschi, Paolo Sbraccia, Eugenia Dogliotti

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Abstract Bariatric surgery (BS) is an effective intervention for severe obesity and associated comorbidities. Although several studies have addressed the clinical and metabolic effects of BS, an integrative analysis of the complex body response to su

Externí odkaz: https://doaj.org/article/5509d46128f84ae98528b65e691d13b7

Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells

Autor: Barbara Pascucci, Donata Orioli, Eugenia Dogliotti, Paola Fortini, Gian Maria Fimia, Sara Baccarini, Chiara De Nuccio, Manuela Lanzafame, Mariarosaria D’Errico, Alessandra Romagnoli, Sergio Visentin, Miriam Savino, Paolo Degan, Ciro Isidoro, Miria Stefanini, A. Calcagnile, Donatella Pietraforte

Publikováno v: Oncotarget
Oncotarget (2016): 102852–102867. doi:10.18632/oncotarget.9913
info:cnr-pdr/source/autori:Pascucci B.; D'Errico M.; Romagnoli A.; De Nuccio C.; Savino M.; Pietraforte D.; Lanzafame M.; Calcagnile A.S.; Fortini P.; Baccarini S.; Orioli D.; Degan P.; Visentin S.; Stefanini M.; Isidoro C.; Fimia G.M.; Dogliotti E./titolo:Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells./doi:10.18632%2Foncotarget.9913/rivista:Oncotarget/anno:2016/pagina_da:102852/pagina_a:102867/intervallo_pagine:102852–102867/volume

The ERCC8/CSA gene encodes a WD-40 repeat protein (CSA) that is part of a E3-ubiquitin ligase/COP9 signalosome complex. When mutated, CSA causes the Cockayne Syndrome group A (CS-A), a rare recessive progeroid disorder characterized by sun sensitivit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a096926e5cae3ca799d3a643636ab09
http://europepmc.org/articles/PMC5732694

The role of mitochondrial dysfunction in Cockayne Syndrome

Autor: Mariarosaria D'Errico, Barbara Pascucci, Alessandra Romagnoli, Chiara De Nuccio, Miriam Savino, Donatella Pietraforte, Manuela Lanzafame, Angelo Salvatore Calcagnile, Paola Fortini, Sara Baccarini, Donata Orioli, Paolo Degan, Sergio Visentin, Miria Stefanini, Ciro Isidoro, Gian Maria Fimia, Eugenia Dogliotti

Publikováno v: Joint Meeting AGI-SIMA, 28-30 Settembre 2015
info:cnr-pdr/source/autori:Mariarosaria D'Errico, Barbara Pascucci, Alessandra Romagnoli, Chiara De Nuccio, Miriam Savino, Donatella Pietraforte, Manuela Lanzafame, Angelo Salvatore Calcagnile, Paola Fortini, Sara Baccarini, Donata Orioli, Paolo Degan, Sergio Visentin, Miria Stefanini, Ciro Isidoro, Gian Maria Fimia, Eugenia Dogliotti/congresso_nome:Joint Meeting AGI-SIMA/congresso_luogo:/congresso_data:28-30 Settembre 2015/anno:2015/pagina_da:/pagina_a:/intervallo_pagine

The ERCC8/CSA gene encodes a WD-40 repeat protein that is part of a E3-ubiquitin ligase/COP9 signalosome complex. When mutated it gives rise to a rare recessive progeroid disorder, Cockayne Syndrome group A (CSA), characterized by sun sensitivity and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::eb0dde1c6230e3b8560366e2baba7fb3
https://publications.cnr.it/doc/337153

HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi sarcoma

Autor: Elena Toschi, Ilaria Bacigalupo, Paolo Monini, Sara Baccarini, Clelia Palladino, Mario Falchi, Federico Bussolino, Laura Malavasi, Donatella Valdembri, Barbara Ensoli, Cecilia Sgadari, Aurelio Cafaro, Patrizia Leone, Roberto Bugarini, Giovanni Rezza, Davide Carlei, Giovanni Barillari

Publikováno v: Nature Medicine. 8:225-232

Treatment with HIV-1 protease inhibitors (PI) is associated with a reduced incidence or regression of Kaposi sarcoma (KS). Here we show that systemic administration of the PIs indinavir or saquinavir to nude mice blocks the development and induces re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d45b61a32d37104950e1bc091fd836c
https://doi.org/10.1038/nm0302-225

[Untitled]

Autor: Sara Baccarini, Avraham Raz, Pratima Nangia-Makker

Publikováno v: Cancer and Metastasis Reviews. 19:51-57

Angiogenesis is required for the continual growth of the tumor and provides a gateway for cells to escape the confines of the primary tumor. Angiogenic stimulus triggers a cascade of functional responses leading to local basement membrane dissolution

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c877ae00601c9a5b2cfd7954c6a493a8
https://doi.org/10.1023/a:1026540129688