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pro vyhledávání: '"Sara B. Jenkins"'
Autor:
Matthew J. Ellis, Marian Taylor, John Hanfelt, Maura E. Redington, K. Siddle, Sara B. Jenkins, Adrian L. Harris, R Leek
Publikováno v:
Breast Cancer Research and Treatment. 52:175-184
IGF1 and IGF2 are circulating peptide hormones and locally-acting growth factors with both paracrine and autocrine functions. IGF1 and IGF2 signal through a common tyrosine kinase receptor, the insulin-like growth factor 1 receptor (IGF1R), and have
Autor:
Stacey A. DaCosta, Adam J. Oates, Matthew J. Ellis, Lisa M. Schumaker, Banu Arun, Amelia A. Pearce, Sara B. Jenkins
Publikováno v:
Breast cancer research and treatment. 47(3)
Loss of heterozygosity (LOH) at the mannose 6-phosphate/insulin-like growth factor 2 receptor gene locus (M6P/IGF2R) on 6q26-27 has recently been demonstrated in approximately 30% of both invasive and in situ breast cancers. LOH was coupled with soma