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pro vyhledávání: '"Sara B. Hereley"'
Publikováno v:
Cancer Research. 70:5496-5496
In addition to drug-target affinity, drug-target residence time is becoming recognized as a critical parameter influencing drug efficacy. Desired compound action can only take place when a drug is interacting with its target protein, which is governe
Publikováno v:
Cancer Research. 70:362-362
There is a great clinical need to develop selective, high affinity kinase inhibitors. While many high throughput kinase activity assays have become readily available, easy-to-use and cost-effective, activity-based assays have significant limitations