Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Sara Antonia, Li"'
Autor:
Rosa I. Sanchez, Sara Antonia Li, F. C. Kauffman, P E Thomas, Valerie K. Turan, J J Li, M A Gallo, A H Conney, S. Mesia-Vela, K R Reuhl
Publikováno v:
Journal of Endocrinology. 183:91-99
Several investigators have suggested that certain hydroxylated metabolites of 17β-estradiol (E2) are the proximate carcinogens that induce mammary carcinomas in estrogen-sensitive rodent models. The studies reported here were designed to examine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf078e1058e359aa6fbe3413414d7127
https://doi.org/10.1677/joe.1.05802
https://doi.org/10.1677/joe.1.05802
Publikováno v:
Molecular Carcinogenesis. 38:97-105
Karyotype and comparative genomic hybridization (CGH) analyses were performed to identify nonrandom/consistent chromosomal alterations in solely estrogen (E)-induced primary ectopic uterine-like stem cell tumors in the kidney (EULTK) of the Syrian ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acea15c41be38d29a14bc966396bc199
https://doi.org/10.1002/mc.10149
https://doi.org/10.1002/mc.10149
Autor:
Marilyn Davis, Saravut John Weroha, Jonathan J. Li, Ossama Tawfik, Xiaoying Hou, Sara Antonia Li
Publikováno v:
Endocrinology. 142:4006-4014
The estrogen-induced and -dependent Syrian hamster renal tumor is the most intensively studied model in estrogen carcinogenesis. Yet, it remains confounding that the kidney of this species behaves as an estrogen target tissue. As both reproductive an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2318356d10216754ffd19a6064251f29
https://doi.org/10.1210/endo.142.9.8355
https://doi.org/10.1210/endo.142.9.8355
Publikováno v:
Carcinogenesis. 19:2173-2180
Both endogenous and exogenous estrogen exposure is associated with an increased breast cancer risk. In some studies, elevated serum testosterone levels have also been linked to an increased breast cancer risk. Estrogen alone or combined with progeste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1164813e99be08be72d890369f78edba
https://doi.org/10.1093/carcin/19.12.2173
https://doi.org/10.1093/carcin/19.12.2173
Publikováno v:
Carcinogenesis. 19:471-477
Ethinylestradiol (EE) has evident paradoxical effects on cancer risk for human breast and hepatic cancer which parallel in some respects its effects on estrogen-induced neoplasms in the hamster kidney and liver. EE has been shown to be only weakly ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d9b485f36ad8f5fde815084c0f50f09
https://doi.org/10.1093/carcin/19.3.471
https://doi.org/10.1093/carcin/19.3.471
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 48:283-286
The estrogen-induced renal tumor in the hamster has emerged as a major animal model in hormonal carcinogenesis. However, a fundamental aspect of this experimental model has as yet not been investigated. In the present study, comparisons between the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5596bdd96153572be65714eb409ccb
https://doi.org/10.1016/0960-0760(94)90157-0
https://doi.org/10.1016/0960-0760(94)90157-0
Publikováno v:
Environmental Health Perspectives
Both natural and synthetic estrogens are capable of inducing renal neoplasms in Syrian hamsters with an incidence approaching 100%. Neither the sequence of events nor the mechanisms involved in estrogen carcinogenesis in this model have been establis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c0635026776448ca9d1c75d039e504
https://doi.org/10.1289/ehp.93101s5259
https://doi.org/10.1289/ehp.93101s5259
Autor:
Jin Wang, Shoulei Jiang, Laszlo Radvanyi, Subrata Sen, Jonathan J. Li, Yan Hong, Sara Antonia Li, Hiroshi Katayama
Publikováno v:
Hormonescancer. 1(1)
Aurora-A is a proto-oncogenic mitotic kinase that is frequently overexpressed in human epithelial malignancies including in breast and ovarian cancers. The mechanism of transcriptional upregulation of Aurora-A in human breast cancer is not yet elucid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea485f8879ba040910d882a648406a51
https://pubmed.ncbi.nlm.nih.gov/21761347
https://pubmed.ncbi.nlm.nih.gov/21761347
Publikováno v:
Hormonescancer. 1(1)
Overexpressed Aurora A, amplified centrosomes, and aneuploidy are salient features of estrogen-induced mammary preinvasive lesions and tumors in female August--Copenhagen Irish (ACI) rats. Intimately involved in these events are cyclins and their ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5bc88362c1f8440eac1eae8c164aab7
https://pubmed.ncbi.nlm.nih.gov/21761349
https://pubmed.ncbi.nlm.nih.gov/21761349
Publikováno v:
Advances in experimental medicine and biology. 617
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c1b257199790343ad4f8ebe6585048f2
https://pubmed.ncbi.nlm.nih.gov/18497045
https://pubmed.ncbi.nlm.nih.gov/18497045