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From Yeast to Mammals, the Nonsense-Mediated mRNA Decay as a Master Regulator of Long Non-Coding RNAs Functional Trajectory

Autor: Sara Andjus, Antonin Morillon, Maxime Wery

Publikováno v: Non-Coding RNA, Vol 7, Iss 3, p 44 (2021)

The Nonsense-Mediated mRNA Decay (NMD) has been classically viewed as a translation-dependent RNA surveillance pathway degrading aberrant mRNAs containing premature stop codons. However, it is now clear that mRNA quality control represents only one f

Externí odkaz: https://doaj.org/article/65bdb09fbb4a40ebaf3381049ef31ebd

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Translation is a key determinant controlling the fate of cytoplasmic long non-coding RNAs

Autor: Sara Andjus, Ugo Szachnowski, Nicolas Vogt, Isabelle Hatin, Chris Papadopoulos, Anne Lopes, Olivier Namy, Maxime Wery, Antonin Morillon

SummaryDespite predicted to lack coding potential, cytoplasmic long non-coding (lnc)RNAs can associate with ribosomes, resulting in some cases into the production of functional peptides. However, the biological and mechanistic relevance of this perva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9102a9b2ce52676cd1be7f69ee89abff
https://doi.org/10.1101/2022.05.25.493276

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From Yeast to Mammals, the Nonsense-Mediated mRNA Decay as a Master Regulator of Long Non-Coding RNAs Functional Trajectory

Autor: Maxime Wery, Antonin Morillon, Sara Andjus

Publikováno v: Non-Coding RNA
Non-Coding RNA, Vol 7, Iss 44, p 44 (2021)
Non-Coding RNA, MDPI, 2021, 7 (3), pp.44. ⟨10.3390/ncrna7030044⟩

International audience; The Nonsense-Mediated mRNA Decay (NMD) has been classically viewed as a translation-dependent RNA surveillance pathway degrading aberrant mRNAs containing premature stop codons. However, it is now clear that mRNA quality contr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08472f28f01b43e94b72554db25038fc
https://doi.org/10.3390/ncrna7030044

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Endogenous RNAi pathway evolutionarily shapes the destiny of the antisense lncRNAs transcriptome

Autor: Sara Andjus, Ugo Szachnowski, Maxime Wery, Dominika Foretek, Antonin Morillon

Publikováno v: Life Science Alliance
Life Science Alliance, Life Science Alliance LLC, 2019, 2 (5), pp.e201900407. ⟨10.26508/lsa.201900407⟩

A genome-wide comparative analysis of “cryptic” aslncRNAs decay in RNAi-capable and RNAi-deficient budding yeasts suggests an evolutionary contribution of RNAi in shaping the aslncRNAs transcriptome.
Antisense long noncoding (aslnc)RNAs are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98993623c125db4d1c230bfe58ef00ec

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