Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sara Alrawashdeh"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Cardiovascular diseases are a major global health concern, responsible for a significant number of deaths each year, often linked to cardiac arrhythmias resulting from dysfunction in ion channels. Hereditary Long QT Syndrome (LQTS) is a condition cha
Externí odkaz:
https://doaj.org/article/8c8e28bede7f487d954db54927791198
Autor:
Abdelouahab Chikhi, El Hassen Mokrani, Abderrahmane Bensegueni, Sara Alrawashdeh, Mohammad A. Ghattas, Dana Emad Eddin Obaid, Ilham Boulhissa
Publikováno v:
Current Computer-Aided Drug Design. 17:214-224
Background: Considering the interesting role in the peptidoglycan biosynthesis pathway, the enzyme UDP-N-acetylglucosamine enolpyruvyl transferase is an attractive target to develop new antibacterial agents. It catalyzes the first key step of this pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8adf698c57617f52fa9215628c4ff838
https://doi.org/10.2174/1573409916666200213124929
https://doi.org/10.2174/1573409916666200213124929
Publikováno v:
Journal of Molecular Graphics and Modelling. 120:108405
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a4b032c1f08d3dac0a3d51c4707cf6b
https://doi.org/10.1016/j.jmgm.2023.108405
https://doi.org/10.1016/j.jmgm.2023.108405
Autor:
Amal M. Youssef, Tariq I. Almundarij, Noor Atatreh, Sara Alrawashdeh, Mohammad Al Sorkhy, Alaa S. Abd-El-Aziz, Ibrahim M. El-Ashmawy, Mohammad A. Ghattas, Amani A. Abdelghani, Khaled B. Alharbi
Publikováno v:
Bioorganic Chemistry. 86:393-400
In this study, the acid chlorides of pyrazolo[3,4-d]pyrimidine compounds were prepared and reacted with a number of nucleophiles. The novel compounds were experimentally tested via enzyme assay and they showed cyclooxygenase-2 inhibition activity in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1896d5708c0dbc9be61fa6f80e724ad3
https://doi.org/10.1016/j.bioorg.2019.02.014
https://doi.org/10.1016/j.bioorg.2019.02.014