Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sara Aharon"'
Autor:
Rakefet Ben-Yishay, Opher Globus, Nora Balint-Lahat, Sheli Arbili-Yarhi, Neta Bar-Hai, Vered Bar, Sara Aharon, Anna Kosenko, Adi Zundelevich, Raanan Berger, Dana Ishay-Ronen
Publikováno v:
Cells, Vol 13, Iss 17, p 1506 (2024)
Epithelial-to-mesenchymal transition (EMT) plays a major role in breast cancer progression and the development of drug resistance. We have previously demonstrated a trans-differentiation therapeutic approach targeting invasive dedifferentiated cancer
Externí odkaz:
https://doaj.org/article/c330496992df471197afa20b6a4dc4ea
Autor:
Shay Golan, Vered Bar, Seth J. Salpeter, Guy Neev, German Creiderman, Daniel Kedar, Sara Aharon, Lubov Turovsky, Adi Zundelevich, Hamutal Shahar, Hagit Shapira, Giuseppe Mallel, Erez Stossel, Nancy Gavert, Ravid Straussman, Zohar Dotan, Raanan Berger, Chani Stossel, Talia Golan, Sharon Halperin, Dan Leibovici, Shani Breuer, Yakir Rottenberg, Liat Applebaum, Ayala Hubert, Hovav Nechushtan, Tamar Peretz, Aviad Zick, Boris Chertin, Dmitry Koulikov, Amir Sonnenblick, Eli Rosenbaum
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionEx vivo organ cultures (EVOC) were recently optimized to sustain cancer tissue for 5 days with its complete microenvironment. We examined the ability of an EVOC platform to predict patient response to cancer therapy.MethodsA multicenter,
Externí odkaz:
https://doaj.org/article/9e606d0806d6437093649828fdd409d0
Autor:
Naamit Deshet-Unger, Galit Horn, Moran Rawet-Slobodkin, Tova Waks, Ido Laskov, Nadav Michaan, Yael Raz, Vered Bar, Adi Zundelevich, Sara Aharon, Lubov Turovsky, Giuseppe Mallel, Seth Salpeter, Guy Neev, Kenneth Samuel Hollander, Ben-Zion Katz, Dan Grisaru, Anat Globerson Levin
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2216 (2022)
High-grade serous ovarian carcinoma (HGSOC) is the most common type of epithelial ovarian cancer. The majority of cases are diagnosed at advanced stages, when intraperitoneal (IP) spread has already occurred. Despite significant surgical and chemothe
Externí odkaz:
https://doaj.org/article/16dbc1696e5e4daea159f67c152a7d9b
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Impaired homeostasis of the carboxylic acids oxalate and citrate, dramatically increases the risk for the formation of Ca2+-oxalate kidney stones, which is the most common form of kidney stones in humans. Renal homeostasis of oxalate and citrate is c
Externí odkaz:
https://doaj.org/article/a909c610d5f2490caed57e58fc4ad393
Autor:
Einav Nili Gal-Yam, Miri Sklair-Levi, Yaeli Vachnish, Nora Balint-Lahat, Dana Morzaev-Sulzbach, Michal Bakalenik-Gavry, Renata Fearmann, Osnat Halshtok, Anat Shalmon, Michael Gotlieb, Yael Yagil, Keren Levanon, Rinat Bernstein-Molho, Amit Itay, Tali Shapira-Rotenberg, Opher Globus, Iris Barshack, Seth Salpeter, Vered Bar, Sara Aharon, Lubov Turovsky, Adi Zundelevich, Giuseppe Mallel, Hamutal Shahar, Hagit Shapira, Maya Dadiani
Publikováno v:
Cancer Research. 82:P1-08
Background. Neoadjuvant chemotherapy (NACT) is increasingly administered for high-risk breast cancer patients. Yet, oncologists lack an effective method for assessing response to treatment beyond clinicpathological features. Organ tissue slices fresh
Autor:
Tomer Shlomi, Orson W. Moe, Liana Shimshilashvili, Nikolay Shcheynikov, Danielle A. Springer, Shmuel Muallem, Moran Fremder, Sara Aharon, Hadar Eini-Rider, Shireen Anbtawee-Jomaa, Ehud Ohana, Elina Aizenshtein, Ahlam Khamaysi, Audrey Noguchi
Publikováno v:
Journal of the American Society of Nephrology
Background In the kidney, low urinary citrate increases the risk for developing kidney stones, and elevation of luminal succinate in the juxtaglomerular apparatus increases renin secretion, causing hypertension. Although the association between stone
Publikováno v:
J Biol Chem
Metabolite transport across cellular membranes is required for bioenergetic processes and metabolic signaling. The solute carrier family 13 (slc13) transporters mediate transport of the metabolites succinate and citrate and hence are of paramount phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::283b8d0a0c92f0cd2957b5c36bac3663
https://europepmc.org/articles/PMC7294084/
https://europepmc.org/articles/PMC7294084/
Autor:
Shay Golan, Yakir Rotenberg, Seth J. Salpeter, Luba Torovsky, Ravid Straussman, Nancy Gavert, Sara Aharon, Dan Leibovici, Zohar A. Dotan, Guy Neev, Hagit Shapira, Eli Rosenbaum, Aviad Zick, Talia Golan, Adi Zundelevich, Vered Bar, Raanan Berger, Shani Breuer, Hamutal Shachar, Ayala Hubert, Hovav Nechushtan
Publikováno v:
Cancer Research. 81:CT209-CT209
Precision cancer therapy has the potential to revolutionize treatment outcome. While genomic analysis has become central to cancer personalized medicine, recent studies have not shown that it drastically improves patient survival as compared to stand